%0 Journal Article
%T 长期口服小剂量胺碘酮致严重肝损伤1例并文献复习<br>Severe Liver Injury Caused By Long-Term Oral Low-Dose Amiodarone: A Case Report and Literature Review
%A 吴连辉
%A 李杰
%J Asian Case Reports in Vascular Medicine
%P 1-5
%@ 2326-3504
%D 2024
%I Hans Publishing
%R 10.12677/acrvm.2024.121001
%X 胺碘酮是常用的广谱抗心律失常药物&#65292;广泛用于治疗和预防多种心律失常性疾病。长期口服胺碘酮可引起心动过缓、甲状腺功能异常、肺毒性、血管异常、胃肠道反应等副作用&#65292;而肝毒性相对少见&#65292;仅有不到1%的患者出现明显的肝毒性&#65292;重度肝损伤更是罕见。现报道1例长期口服小剂量胺碘酮引起的重度肝损伤&#65292;讨论病因临床特点、治疗及预后&#65292;为口服胺碘酮用药安全提供参考。<br>Amiodarone is a common broad-spectrum antiarrhythmic drug, which is widely used to treat and prevent a variety of arrhythmia diseases. Long-term oral amiodarone can cause bradycardia, thyroid dysfunction, pulmonary toxicity, vascular abnormalities, gastrointestinal reactions and other side effects, while hepatotoxicity is relatively rare, with less than 1% of patients showing obvious hepatotoxicity, and severe liver injury is even rarer. This paper reports a case of severe liver injury caused by long-term oral low-dose amiodarone, and discusses the etiology, clinical characteristics, treatment and prognosis, so as to provide reference for the safety of oral amiodarone.
%K 药物性肝损伤&#65292
%K 口服胺碘酮<br>Drug-Induced Liver Injury
%K Oral Amiodarone
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=92898