%0 Journal Article %T Enfermedad de Marburg como variante de esclerosis m¨²ltiple: presentaci¨®n de un caso at¨ªpico %A Carvajal %A Tomas %A Franco %A Diana L %A Mart¨ªnez %A Adriana %A Pe£¿a %A Iv¨¢n M %J Acta Neurol¨®gica Colombiana %D 2012 %I Scientific Electronic Library Online %X we present a 58 years old woman with multiple sclerosis diagnosed in 2007, she was treated with interferon and methylprednisolone with a stable disease until last year. recently she had had multiple episodes of exacerbations. patient was admitted for a rapidly progressive neurological deterioration. when evaluated the patient had a glasgow scale of 4/15 (best eye response: 2, best verbal response: 1, best motor response: 1). case was evaluated in a medical board, and was considered an atypical marburg variant of multiple sclerosis. she was treated with immunoglobulin and mitoxantrone without clinical improvement. later she developed a distributive shock leading to death. %K multiple sclerosis. %U http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0120-87482012000200006&lng=en&nrm=iso&tlng=en