%0 Journal Article %T Utilidad de anticuerpos antiacuaporinas 4 en el diagn¨®stico de neuromielitis ¨®ptica %A Mart¨ªnez Villota %A Viviana Alexandra %J Acta Neurol¨®gica Colombiana %D 2011 %I Scientific Electronic Library Online %X neuromyelitis optica or devic syndrome is a severe demyelinating syndrome. this entity although of low prevalence represents a diagnostic and therapeutic challenge, especially at the moment of differentiation with multiple sclerosis. with the discovery of aquaporin-4 specific serum autoantibody, in the pathophysiology of this syndrome, we have expanded the tools to make a diagnosis with greater certainty and identify options for treatment. here is an update of the literature regarding its role in the diagnosis and treatment of neuromyelitis optica. %K neuromyelitis optica %K aquaporin-4 %K aquaporin-4 specific serum autoantibody %K demyelinating diseases %K optic neuritis %K transverse mielitis. %U http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0120-87482011000300007&lng=en&nrm=iso&tlng=en