%0 Journal Article
%T Resultados de implante de semillas de iodo-125 con sistema de preplanificaci¨®n en 250 pacientes con carcinoma de pr¨®stata
%A Guinot
%A J.L.
%A Ric¨®s
%A J.V.
%A Gimeno
%A J.
%A Tortajada
%A M.I.
%A Carrascosa
%A M.
%A Santos
%A M.
%A Casanova
%A J.
%A Soler
%A P.
%A Crisp¨ªn
%A V.
%A Arribas
%A L.
%J Actas Urol¨®gicas Espa£¿olas
%D 2011
%I Scientific Electronic Library Online
%R 10.4321/S0210-48062011000600005
%X introduction: we review the experience with prostate carcinoma patients treated with permanent implants of 125-i seeds and the outcome eight years after the beginning of this technique. material and methods: from 2002 to 2007 we have performed 250 implants with ldr brachytherapy with rapidstrand£¿ and preplanning system. mean age was 68 (49-78). mean psa was 7.32 (2.31 - 14.6). t1-t2a was the stage in 98%, and gleason < 6 in 96%. low risk cases were 81% and intermediate risk 19% (ten of them received 46gy ebrt). hormonal treatment was used in 42%. results: with a mean follow-up of 48 months, 14 patients (5.7%) showed biochemical failure (bf). eleven patients (4.5%) with theoretical bf were observed and psa decreased without treatment. actuarial psa relapse-free survival at 5 years was 91%, (92% low risk, 86% intermediate cases), and 92% vs 81% with psa <10 vs >10 (p<0.05). rectum complications were g2 in 0.6%. a urinary catheter was necessary in 6.5%. sexual function was conserved in 60%. mean v100 was 89% and d90 143gy. conclusion: the outcome of patients with low risk prostate carcinoma treated with i-125 seed is very good with very low complications rate. cases with psa bounces should be controlled before starting a salvage treatment.
%K prostate
%K 125-i seeds
%K brachytherapy
%K real-time.
%U http://scielo.isciii.es/scielo.php?script=sci_abstract&pid=S0210-48062011000600005&lng=en&nrm=iso&tlng=en