%0 Journal Article
%T 1H AND 13C NMR SPECTRAL ASSIGNMENTS AND X-RAY CRYSTALLOGRAPHY OF 4,5,8,12b-TETRAHYDRO-ISOINDOLO[1,2 -¦Á ]ISOQUINOLINE AND DERIVATIVES
%A CASTRO-CASTILLO
%A VICENTE
%A GALD¨¢MEZ
%A ANTONIO
%A REBOLLEDO-FUENTES
%A MARCO
%A CASSELS
%A BRUCE K
%J Journal of the Chilean Chemical Society
%D 2012
%I Scientific Electronic Library Online
%R 10.4067/S0717-97072012000100004
%X 12b-hydroxy-5,6,8,12b-tetrahydroisoindolo[1,2-¦Á] isoquinolin-8-one (4), 5,6,8,12b-tetrahydroisoindolo[1,2-¦Á]isoquinoline (5) and 12b-hydroxy-5,6,8,12b-tetrahydroisoindolo[1,2-¦Á]isoquinoline (6) were obtained by reduction of 4,5,8,12b-tetrahydroisoindolo[1,2-¦Á]isoquinolin-8-one (3) with lialh4/thf/n2. the precursor and products were characterized by nmr spectroscopy and the x-ray crystal structure of 5 hydrochloride monohydrate (5a) was determined. 1h and 13c nmr spectra were completely assigned for compounds 3, 4, and 5a, using two-dimensional experiments (h-h cosy, hmqc, hmbc and h-h noesy).
%U http://www.scielo.cl/scielo.php?script=sci_abstract&pid=S0717-97072012000100004&lng=en&nrm=iso&tlng=en