%0 Journal Article
%T Terapia focal en c¨¢ncer de pr¨®stata: una potencial estrategia para solucionar el problema del sobretratamiento
%A Lecornet
%A Emilie
%A Ahmed
%A Hashim Uddin
%A Moore
%A Caroline
%A Emberton
%A Mark
%J Archivos Espa£¿oles de Urolog¨ªa (Ed. impresa)
%D 2010
%I Scientific Electronic Library Online
%R 10.4321/S0004-06142010001000003
%X focal therapy involves destroying the cancer focus and the tissue surrounding the cancer in order to offer patients the potential of combining cancer control with minimal side-effects. current standard of care involve either surveillance or radical therapy. neither of these is ideal. active surveillance carries risk of under-treatment, psychological morbidity as a result of anxiety and is not without side-effects due to repeated biopsies., although radical therapy is the gold standard for curative treatment it carries risks of over-treatment with its numerous side-effects. with the proportion of unifocal or unilateral disease among men with low-risk disease rising, a focal approach could avoid both under and over-treatment. with the advent of improved accuracy for cancer localization provided by multi-parametric mri and new biopsy strategies such as transperineal mapping biopsies, ablative modalities such as cryotherapy, high intensity focused ultrasound, photodynamic therapy and radio-interstitial tumour ablation make a focal treatments a real possibility.
%K focal therapy
%K cryotherapy
%K hifu
%K photodynamic therapy
%K prostate cancer.
%U http://scielo.isciii.es/scielo.php?script=sci_abstract&pid=S0004-06142010001000003&lng=en&nrm=iso&tlng=en