%0 Journal Article
%T El nuevo paradigma de la hemocromatosis neonatal: hepatitis fetal aloinmunitaria
%A Costaguta
%A Alejandro
%A ¨¢lvarez
%A Fernando
%J Archivos argentinos de pediatr£¿-a
%D 2012
%I Sociedad Argentina de Pediatria
%X the classical model of neonatal hemochromatosis was based on the analogy with hereditary hemochromatosis. medical treatment consisted on the antioxidant-chelator cocktail. the new hypothesis of an alloimmune origin of the process by which the pregnant woman mounts an igg-based destructive response against fetal hepatocytes offers a pathogenic explanation, allowing treatment to be focused on the immunological aspects, with excellent results, and opens the possibility of preventive treatment in future pregnancies. this new paradigm produces a deep impact in diagnosis, prognosis and treatment of the disease, that should be called "fetal alloimmune hepatitis".
%K hemochromatosis
%K neonatal
%K hepatitis
%K alloimmune.
%U http://www.scielo.org.ar/scielo.php?script=sci_abstract&pid=S0325-00752012000300008&lng=en&nrm=iso&tlng=en