%0 Journal Article
%T Falla hep¨¢tica secundaria a toxicidad por tuberculost¨¢ticos: Caso cl¨ªnico
%A Malla
%A Ivone
%A Fauda
%A Mart¨ªn
%A Casanueva
%A Enrique
%A Fern¨¢ndez
%A Mar¨ªa Isabel
%A Amante
%A Marcelo
%A Cheang
%A Yu
%A Giacove
%A Gisela
%A Pedreira
%A Alejandra
%A Petracca
%A Pablo
%A Gonz¨¢lez Campa£¿a
%A Ariel
%A Silva
%A Marcelo
%A Podest¨¢
%A Gustavo
%J Archivos argentinos de pediatr£¿-a
%D 2012
%I Sociedad Argentina de Pediatria
%X hepatoxicity of isoniazid, mainly in association with rifampin, is a rare secondary effect of tuberculostatic treatment. in the united states, it accounts for 0.2% of all pediatric orthotropic liver transplant, and 14% of transplants for drug hepatotoxicity. we report the case of a 10 year-old patient who presented with acute liver failure requiring orthotropic liver transplant after forty days of tuberculostatic treatment with isoniazid, rifampin and pyrazinamide.
%K antitubercular agents
%K isoniazid
%K acute liver failure
%K liver transplantation.
%U http://www.scielo.org.ar/scielo.php?script=sci_abstract&pid=S0325-00752012000300011&lng=en&nrm=iso&tlng=en