%0 Journal Article
%T Factors associated with epidemic multiresistant Pseudomonas aeruginosa infections in a hospital with AIDS-predominant admissions
%A Gomes
%A Marisa Zenaide Ribeiro
%A Oliveira
%A Raquel Vasconcellos C. de
%A Machado
%A Carolina Romero
%A Concei£¿£¿o
%A Magda de Souza da
%A Souza
%A Cristina Vieira de
%A Louren£¿o
%A Maria Cristina da Silva
%A Asensi
%A Marise Dutra
%J Brazilian Journal of Infectious Diseases
%D 2012
%I Brazilian Society of Infectious Diseases
%R 10.1590/S1413-86702012000300001
%X introduction: infections caused by multiresistant pseudomonas aeruginosa (mr-pa) have been associated with persistent infections and high mortality in acquired immunodeficiency syndrome (aids) patients. therefore, understanding the predisposing factors for infection/colonization by this agent is critical for controlling outbreaks caused by mr-pa in settings with aids patients. objectiveand methods: to analyze the presence of factors associated with the acquisition of an epidemic mr-pa strain in a hospital with aids-predominant admission. a case-control study was carried out in which cases and controls were gathered from a prospective cohort of all hospitalized patients in an infectious disease hospital during a five-year study period. results: multivariate logistic regression analysis demonstrated that enteral nutrition or = 14.9), parenteral nutrition (or = 10.7), and use of ciprofloxacin (or = 8.9) were associated with a significant and independent risk for mr-pa acquisition. conclusions: although cross-colonization was likely responsible for the outbreaks, the use of ciprofloxacin was also an important factor associated with the acquisition of an epidemic mr-pa strain. more studies are necessary to determine whether different types of nutrition could lead to modification of gastrointestinal flora, thereby increasing the risk for infection/colonization by mr-pa in this population.
%K pseudomonas aeruginosa
%K risk factors
%K disease outbreaks
%K molecular epidemiology
%K acquired immunodeficiency syndrome.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1413-86702012000300001&lng=en&nrm=iso&tlng=en