%0 Journal Article
%T The protective effects of Baypamun£¿HK in mice experimentally infected with Toxoplasma gondii
%A Cunha
%A Eva Laurice Pereira
%A Silva
%A Rodrigo Costa da
%A Da Silva
%A Aristeu Vieira
%A Langoni
%A H¨¦lio
%J Brazilian Journal of Veterinary Research and Animal Science
%D 2004
%I Universidade de S?o Paulo
%R 10.1590/S1413-95962004000300004
%X the present work aimed to verify the effects of baypamun£¿hk on the survival of albinic mice, experimentally infected with toxoplasma gondii rh strain, treated or not with sulfadiazine-pirimetamine, as well as on the formation and the number of brain cysts. four groups of 20 mices were inoculated with 105 tachizoites, subcutaneously, and undergone to different treatments. serum tests were carried out by indirect immunofluorescence and samples of brain, liver and lung were collected from animals who died for cytological and brain cysts examinations. after 60 days, all survivors were sacrificed. isolated baypamun£¿hk didn't present a protective action against the infection by t. gondii, but its association sulfadiazine-pirimetamine, a specific treatment caused a higher survival of animals and a more intense and longer antibody responses.
%K toxoplasma gondii
%K baypamun£¿hk
%K indirect immunofluorescence
%K mice.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1413-95962004000300004&lng=en&nrm=iso&tlng=en