%0 Journal Article
%T Avalia£¿£¿o da capacidade adjuvante do cloreto de dimetildioctadecilam£¿nio associado ao hidr¨®xido de alum¨ªnio na indu£¿£¿o da resposta imune humoral de bovinos vacinados com o v¨ªrus da diarr¨¦ia viral bovina
%A Silva
%A Luis C¨¦sar da
%A Takiuchi
%A Elisabete
%A M¨¦dici
%A Kerlei Cristina
%A Alfieri
%A Alice Fernandes
%A Alfieri
%A Amauri Alcindo
%J Brazilian Journal of Veterinary Research and Animal Science
%D 2004
%I Universidade de S?o Paulo
%R 10.1590/S1413-95962004000300009
%X the humoral immune response of cattle vaccinated with inactivated bovine viral diarrhea virus (bvdv) using the association of dimethyl dioctadecyl ammonium chloride (dda-chloride) and aluminum hydroxide (vaccine b) as adjuvant, was compared with the same antigenic formulation adsorbed with only aluminum hydroxide (vaccine a). the neutralizing antibodies titers were assessed two weeks after the second vaccine dose. the animals that received vaccine b had better humoral responses than the calves vaccinated with vaccine a. the mean titers of neutralizing antibodies, expressed in log2, for the calves that received vaccine b was higher to those observed in group vaccinated with vaccine a. these results show that the inclusion of dda chloride in vaccine formulations adsorbed with aluminum hydroxide determine a better humoral immune response in cattle vaccinated with bvdv inactivated.
%K cattle
%K bovine viral diarrhea virus
%K dimethyl dioctadecyl ammonium chloride
%K vaccine
%K adjuvant.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1413-95962004000300009&lng=en&nrm=iso&tlng=en