%0 Journal Article
%T An antimicrobial alkaloid and other metabolites produced by Penicillium sp. An endophytic fungus isolated from Mauritia flexuosa L. f.
%A Koolen
%A Hector Henrique Ferreira
%A Soares
%A Elzalina Ribeiro
%A Silva
%A Felipe Moura Ara¨²jo da
%A Almeida
%A Richardson Alves de
%A Souza
%A Afonso Duarte Le£¿o de
%A Medeiros
%A L¨ªvia Soman de
%A Rodrigues Filho
%A Edson
%A Souza
%A Antonia Queiroz Lima de
%J Qu¨ªmica Nova
%D 2012
%I Sociedade Brasileira de Qu¨ªmica
%R 10.1590/S0100-40422012000400022
%X the alkaloid glandicoline b (1) and six other compounds: ergosterol (2), brassicasterol (3), ergosterol peroxide (4), cerevisterol (5), mannitol (6) and 1-o-¦Á-d-glucopyranoside (7) were isolated from penicillium sp. strain pbr.2.2.2, a fungus from mauritia flexuosa roots. the structures of the isolated metabolites were established by spectral analysis. meoh extract of the fungal mycelium at 500 ¦Ìg ml-1 exhibited antimicrobial activity against staphylococcus aureus and the compound 1 at 100 ¦Ìg ml-1 was active against s. aureus, micrococcus luteus and escherichia coli. the relationship between the bioactive properties of the fungus pbr.2.2.2 and those achieved for glandicoline b, as well the potential of this substance as bactericide is discussed.
%K penicillium
%K mauritia flexuosa
%K glandicoline b.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0100-40422012000400022&lng=en&nrm=iso&tlng=en