%0 Journal Article
%T Desenvolvimento e valida£¿£¿o de m¨¦todo anal¨ªtico para a determina£¿£¿o de sulfassalazina em suspens£¿o oral: compara£¿£¿o do m¨¦todo espectrofotom¨¦trico e de cromatografia l¨ªquida de alta efici¨ºncia (CLAE)
%A Costa
%A Mayre Aparecida Borges da
%A Ricci-J¨²nior
%A Eduardo
%A Santos
%A Elisabete Pereira dos
%A Mansur
%A Claudia Regina Elias
%A Campos
%A Vania Emerich Bucco de
%J Qu¨ªmica Nova
%D 2012
%I Sociedade Brasileira de Qu¨ªmica
%R 10.1590/S0100-40422012000400028
%X sulfasalazine is a prodrug used in the treatment of the chron's disease and rheumatoid arthritis. two analytical methods for analysis of sulfasalazine in oral suspension were validated using spectrophotometric and hplc. there is not any pharmacopoeic method to assay sulfasalazine in oral suspension. the methods are insurance and fast execution for the quality control. both, suspension and tablets 500 mg (azulfin£¿) had been analyzed by methods using uv/vis and hplc and the results were satisfactory.
%K sulfasalazine
%K oral suspension
%K analytical method.
%U http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0100-40422012000400028&lng=en&nrm=iso&tlng=en