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Feb 06, 2026Open    Access

Enhancing Norfloxacin’s Solubility and Antibacterial Activity through Pharmaceutical Salt Formation with Fluorobenzoic Acids

Shuhui Wang,Jiashu He,Chenyu Ruan,Panyue Cao,Ziyi Zhang,Chengjun Jiang
Norfloxacin (NOR), a broad-spectrum fluoroquinolone antibiotic, is widely used to treat bacterial infections. However, its clinical application is hindered by poor aqueous solubility and low oral bioavailability. To address these limitations, this study developed two novel pharmaceutical salts of NOR using 4-fluorobenzoic acid (4-FA) and 2-fluorobenzoic acid (2-FA) as counterions. The salts were synthesized via slow evaporation crystallization, and their structures were characterized by single-c...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114832


Feb 06, 2026Open    Access

The Role of Parenting in the Proliferation of Street Children: Evidence from River Oli Division, Arua City, Uganda

Laloyo Stella Apecu,Ndaru Zabibu
Street children remain a persistent social and child?protection challenge in many urban areas of Sub?Saharan Africa. This study examined the role of parenting in the proliferation of street children in River Oli Division, Arua City, Uganda. Using a qualitative case?study design, data were collected from 30 street children through in?depth interviews and focus group discussions, alongside parents and community leaders. Thematic analysis revealed that inadequate parenting characterized by poverty,...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114827


Feb 06, 2026Open    Access

Guillain-Barré Syndrome Presenting as Pseudo-Cerebellar Syndrome: A Case Report from a Resource-Limited Setting in Sub-Saharan Africa

Cheick Ousmane Soumah,Mohamed Tafsir Diallo,Mohamed Lamine Touré,Souleymane Djigué Barry,Fodé Abass Cissé
Guillain-Barré Syndrome (GBS) is the most frequent cause of acute flaccid paralysis worldwide, with significant morbidity and mortality in the absence of timely treatment. It is an immune-mediated acute inflammatory poly-radiculoneuropathy, usually triggered by infection. While the classical presentation is ascending symmetrical weakness with areflexia, atypical forms may mimic other neurological disorders and delay diagnosis. We report a rare pseudo-cerebellar presentation in a middle-aged man ...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114127


Feb 05, 2026Open    Access

Improving Rice Productivity in Liberia through Integrated Soil Fertility Management (ISFM)

Melvin W. Bee
Agriculture departments in Liberia, along with partner organizations in the development of the agricultural sector, are using Integrated Soil Fertility Management (ISFM) modeling, soil diagnostics, and sensitivity analysis to address soil fertility issues and thereby improving rice productivity. Through a Mitscherlich, based yield model, the study investigated nitrogen response under differing organic matter inputs, whereas the nutrient, use efficiency (NUE) and carbon (SOC) long, term soil orga...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114853


Feb 05, 2026Open    Access

From Policy to Practice: Equity Implications of Contextualized, Localized, and Indigenized Curriculum

Erwin B. Marcelo
This article examines the equity implications of implementing contextualized, localized, and indigenized curricula in basic education, with emphasis on Philippine K to 12 reforms and Indigenous school settings such as the Navajo Nation. Anchored in the Enhanced Basic Education Act of 2013 and related Department of Education policies, the analysis treats curriculum contextualization as a legal and ethical requirement for quality and equity rather than a discretionary pedagogical option. Drawing o...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114746


Feb 05, 2026Open    Access

Preliminary Success in Hormone-Induced Breeding of Wallago attu by Stripping in Bangladesh

Md. Shariful Islam,Md. Amirul Islam,Md. Shariful Islam
Boal fish or Indian major catfish are generally available in large river, swamps and freshwater lakes but now-a-days those natural habitats are severely degraded. This decreasing rate of Boal fish can be reduced through natural restoration, and breeding practices should be increased. This is the first attempt to breeding Boal fish through hormone-induced breeding by stripping in Bangladesh. The ovulation and fertilization rate was found 90% - 95% and 75% - 85%. Unfortunately, after the gastrula ...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114739


Feb 05, 2026Open    Access

The Influence of Holistic Transformation on Community Development in Eastern Uganda Namely: Jinja City, Mbale City, Tororo District, Soroti City and Katakwi District

Fakhri Mohamed,Oina Maxwell,Besiima Gertrude,Ikilai Isaac
This study examined the influence of holistic transformation on community development in Eastern Uganda. The study was guided by three specific objectives: to assess the influence of physical, psychological, and spiritual transformation on community development. A case study research design was adopted, employing a quantitative approach to collect the required data. Out of 236 questionnaires distributed, 230 were successfully returned, representing a response rate of 97.45%. Data obtained from t...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114680


Feb 05, 2026Open    Access

Investigating Effects of Direction of Sampling on the Tensile Properties of Cows Leather Treated with Sulphonated Synthetic Fatliquor of Different Concentrations

Edwin Wanjala Musawa,Michael Nakitare Waswa,Kallen Mulilo Nalianya
Diverse applications of collagen-based materials such as leather have sparked research interest that seek to investigate the effect of fatliqours on their physical and mechanical properties. As the applications of these collagen materials increases such as in the field of medicine, footwear and upholstery, more studies are required to gain more insight on how their quality and durability can be improved. Leather being one of the collagen-based material is a by-product of the meat industry, made ...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114323


Feb 05, 2026Open    Access

Growth, Development and Yield of Component Crops in a Maize-Cowpea Intercrop System in the Sudan Savannah Zone in Ghana

Listowell Aditwin Akologo,Harrison Kwame Dapaah,Margaret Esi Essifie,Julius Yirzagla,Emmanuel Aziiba Asibi
A maize-cowpea intercrop multi-location study was conducted at the experimental fields of the Council for Scientific and Industrial Research-Savannah Agricultural Research Institute (CSIR-SARI) at Manga, Binduri District and at the Presbyterian Agricultural Station (PAS) at Garu, in the Garu District from July to October 2021 and 2022 cropping seasons. The objective of the study was to determine the influence of a maize-cowpea intercrop system on the growth, development and yield of maize and co...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1112768


Feb 04, 2026Open    Access

The Impact of Social Media Usage on Consumers’ Purchase Intentions. Using Perceived Value as the Mediator 

Matilda Kumi,Sebastian Nana Kumi,Newlove Sulun Senkpeni,Francisca Arboh,Edwin Akwandoh,Tejan Andrew Rollings Kamara
The widespread use of social media has made it an essential marketing tool that significantly influences consumers’ purchasing intentions. However, little is known about the psychological mechanism underlying this influence, notably the mediating function of perceived value, particularly in quickly digitalizing situations such as Ghana. In order to examine how Social Media Usage (SMU) affects Customer Purchase Intention (CPI), this study combines Persuasive Theory and Social Interactive Theory, ...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114852


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