Aging and End Stage Renal Disease Cause A Decrease in Absolute Circulating Lymphocyte Counts with A Shift to A Memory Profile and Diverge in Treg Population

David-Neto Elias,Fabiana Agena,Francine Brambate Carvalhinho Lemos,Geraldo Rubens Ramos Freitas,Maria da Luz Fernandes,Nelson Zocoler Galante,Omar Jaluul,Sérgio Colenci Silva,Ver？nica Coelho

Increased Inflammatory Response in Old Mice is Associated with More Severe Neuronal Injury at the Acute Stage of Ischemic Stroke

Fanxia Shen,Frank Han,Hua Su,Lidan Jiang,Vincent Degos

Rosenroot (Rhodiola): Potential Applications in Aging-related Diseases

Fei Chen,Lifeng Yue,Wei Zhuang,Xiaofang Dang,Yuewen Gong,Yumin Luo

Influence of Environment and Lifestyle on Incidence and Progress of Amyotrophic Lateral Sclerosis in A German ALS Population

Antonia Zapf,Bo？enna Kuraszkiewicz,Hanna Goszczynska,Johanna Kammeyer,Julian Grosskreutz,Magdalena Kuzma-Kozakiewicz,Mamede de Carvalho,Maria Piotrkiewicz,Marta Gromicho,Peter M. Andersen,Susanne Petri

MicroRNAs and the Genetic Nexus of Brain Aging, Neuroinflammation, Neurodegeneration, and Brain Trauma

Ashley E. Russell,Elizabeth B. Engler-Chiurazzi,James W. Simpkins,Keyana N. Porter,Saumyendra N. Sarkar

Significance of Complement System in Ischemic Stroke: A Comprehensive Review

Guo-Yuan Yang,Yanqun Liu,Yuanyuan Ma

Increased Serum C-reactive Protein and Corpus Callosum Alterations in Older Adults

Chantal Meslin,Fabienne Cyprien,Jerome Maller,Karen Ritchie,Marie-Laure Ancelin,Philippe Courtet,Sylvaine Artero

Subclinical Hypothyroidism: is it Really Subclinical with Aging?

Anne Charrié,Anne Fran？ois-Joubert,Anne Mayer,Anne-Sophie Gauchez,Antoine Vignoles,Catherine Ronin,Charles Thivolet,Christine Waterlot,Claire Falandry,Domitille Guédel,Elisabetta Kuczewski,Emmanuel Disse,Hélène Du Boullay,Jean-Cyril Bourre,Karim Chikh,Muriel Rabilloud,Pierre-Yves Brard,Rapha？lle Andréani,Robin Gourmelon,Sandrine Donadio-Andréi,Thomas Gilbert

The Anti-Inflammatory and Anti-Oxidant Mechanisms of the Keap1/Nrf2/ARE Signaling Pathway in Chronic Diseases

Hong Sha,Hong Wang,Qiang Liu,Wenjun Tu

Reactive Astrocytes in Neurodegenerative Diseases

Jialin Zheng,Jiatong Li,Kunyu Li

Longevity Effect of Liuwei Dihuang in Both Caenorhabditis Elegans and Aged Mice

Hua Yang,Jiahao Shi,Jian Fei,Jinzeng Wang,Mengjie Zhang,Ning Wang,Ping Yang,Sai Yang,Tianpei Xie,Weidong Chen,Xu Yang

Distribution Pattern of Atherosclerotic Stenosis in Chinese Patients with Stroke: A Multicenter Registry Study

Binbin Song,Chunmei Zhang,Chunxia Wu,Delin Yu,Heng Zhang,Jianwei Li,Jingfen Zhang,Jingxin Zhong,Ling Wang,Lingyun Jia,Pinjing Hui,Xiaofang Pan,Xiaoyu Cai,Xiufang Sui,Xuan Meng,Yalan Fang,Yingqi Xing,Youhe Jin,Yuhong Zhu,Yuming Mu

Reduction in IGF1 mRNA in the Human Subependymal Zone During Aging

Christin Weissleder,Cynthia Shannon Weickert,Guy Barry,Kay L. Double,Maree J. Webster,Matthew W. Wong,Samantha J. Fung

Epigenetic Regulation of Bone Marrow Stem Cell Aging: Revealing Epigenetic Signatures associated with Hematopoietic and Mesenchymal Stem Cell Aging

Dimitrios Cakouros,Stan Gronthos

LMNA-mutated Rabbits: A Model of Premature Aging Syndrome with Muscular Dystrophy and Dilated Cardiomyopathy

Di Liu,Hongsheng Ouyang,Jichao Deng,Mao Chen,Tingjun Liu,Tingting Sui,Yuanyuan Xu,Yuning Song,Zhanjun Li

REST rs3796529 Genotype and Rate of Functional Deterioration in Alzheimer’s Disease

Cheng-Sheng Chen,Chiou-Lian Lai,Hsuan-Yu Chen,Mei-Chuan Chou,Poyin Huang,Ya-Hsuan Chang,Yuan-Han Yang

Overweight in the Elderly Induces a Switch in Energy Metabolism that Undermines Muscle Integrity

Adrian Rubio-Gonzalez,Ana Coto-Montes,Beatriz Caballero,Ignacio Vega-Naredo,Jose A. Boga,Jose M. Arche,Juan C. Bermejo-Millo,Juan J. Solano,Mamen Oliván,Manuel Bermudez,María Fernandez-Fernández,Yaiza Potes,Zulema Pérez-Martinez

Prospective Study of Glycated Hemoglobin and Trajectories of Depressive Symptoms: The China Health and Retirement Longitudinal Study

Anxin Wang,Deqiang Zheng,Haibin Li,Jin Guo,Lixin Tao,Qi Gao,Wei Feng,Wei Wang,Xia Li,Xiaonan Wang,Xiuhua Guo

Processing of Mutant β-Amyloid Precursor Protein and the Clinicopathological Features of Familial Alzheimer’s Disease

Bin Li,Christopher Bi,Stephanie Bi

Habitual Meat Consumption and Changes in Sleep Duration and Quality in Older Adults

Alberto Lana,Arthur E. Mesas,Auxiliadora Graciani,Ellen A. Struijk,Fernando Rodriguez-Artalejo,Lucía Arias-Fernandez

Collagen XIX Alpha 1 Improves Prognosis in Amyotrophic Lateral Sclerosis

Adrián Galiana,Alberto García Redondo,Alexandra Juárez Rufián,Christian Lunetta,Claudia Tarlarini,Elena Pegoraro,Gabriela Atencia Cibreiro,Gianni Sorarù,Jesús Esteban,Jesús Mora,José L. Mu？oz-Blanco,Juan F. Roy,Juan M. Cano,Laura Moreno,Lucía Galán,Marina Mora,María J. Mu？oz,Miguel A. Martín,Paz Torre Merino,Pilar Cordero Vázquez,Pilar Larrodé,Pilar Zaragoza,Rosario Osta,Silvana Penco

Efficacy and Safety of the Pneumococcal Conjugate-13 Valent Vaccine in Adults

Fawziah Marra,Nirma Khatri Vadlamudi

Age as an Independent Risk Factor for Diabetic Peripheral Neuropathy in Chinese Patients with Type 2 Diabetes

Bin Lu,Fei Mao,Hangping Zheng,Siying Liu,Xiaoming Zhu,Xiaona Qiao

BDNF Alleviates Neuroinflammation in the Hippocampus of Type 1 Diabetic Mice via Blocking the Aberrant HMGB1/RAGE/NF-κB Pathway

Jianbo Xiu,Lanlan Li,Nannan Sun,Rongrong Han,Shu Liu,Yan Shen,Zeyue Liu

The WNK-SPAK/OSR1 Kinases and the Cation-Chloride Cotransporters as Therapeutic Targets for Neurological Diseases

Dandan Sun,Huachen Huang,Jinwei Zhang,Kristopher T. Kahle,Shanshan Song,Suneel Banerjee,Tong Jiang

The Neuronal Activation of Deep Cerebellar Nuclei Is Essential for Environmental Enrichment-Induced Post-Stroke Motor Recovery

Chuan-jie Wang,Jun-fa Wu,Ming-yue Li,Qi-li Shi,Qun Zhang,Xin Wang,Yi Wu

Th1 Biased Progressive Autoimmunity in Aged Aire-Deficient Mice Accelerated Thymic Epithelial Cell Senescence

Abudureyimujiang Aili,Jie Zhang,Qing Ge,Rong Jin,Xiuyuan Sun,Xuewen Pang,Yuqing Wang

Quantitative Evaluation of Gait Disturbance on an Instrumented Timed Up-and-go Test

Kazuo Yamamoto,Masatsune Ishikawa,Shigeki Yamada,Yukihiko Aoyagi

Metformin and the Risk of Dementia in Type 2 Diabetes Patients

Tseng Chin-Hsiao

Snapshot: Implications for mTOR in Aging-related Ischemia/Reperfusion Injury

Changhong Shi,Dong Liu,Jiansong Yuan,Liqun Xu,Shubin Qiao,Xiaoyan Zhang

DRAM is Involved in Hypoxia/Ischemia-Induced Autophagic Apoptosis in Hepatocytes

Dongjie Liu,Jianji Xu,Jieling Wang,Tongwang Yang,Xiaoni Liu,Yanjun Wang,Yunjin Zang

Prospective Views for Whey Protein and/or Resistance Training Against Age-related Sarcopenia

Andreas K. Nüssler,Liangkai Chen,Liegang Liu,Qian Cheng,Wei Bao,Wei Yang,Yan Zhang,Yuxiao Liao,Zhao Peng

Elevated Inflammatory Status and Increased Risk of Chronic Disease in Chronological Aging: Inflamm-aging or Inflamm-inactivity?

Andres E. Carrillo,Melissa M. Markofski

Involvement of the MiR-181b-5p/HMGB1 Pathway in Ang II-induced Phenotypic Transformation of Smooth Muscle Cells in Hypertension

Cheng-Long Zhang,Feng-Juan Li,Tian-Lun Yang,Xiu-Ju Luo

Intensive Lipid-Lowering Therapy Ameliorates Asymptomatic Intracranial Atherosclerosis

Changhong Ren,Han Wang,Huijuan Miao,Linyu Huo,Mengnan Wang,Ming Ren,Qi Yang,Xiuhai Guo,Xunming Ji,Yinghua Zhou,Yujiao Yang

MicroRNAs or Long Noncoding RNAs in Diagnosis and Prognosis of Coronary Artery Disease

Han Ding,Hongzhao Qi,Lei Zhang,Sheng Xue,Yu Wang,Yuan Zhang

Redefining Chronic Inflammation in Aging and Age-Related Diseases: Proposal of the Senoinflammation Concept

Arnold Y. Seo,Bonggi Lee,Dae Hyun Kim,Dong Soon Im,Eun Kyeong Lee,Eunok Im,Hae Young Chung,Jae Heun Chung,Jaewon Lee,Ki Wung Chung,Nam Deuk Kim,Sangwoon Chung,Yeon Ja Choi,Young Suk Jung

The Role of Pathological Aging in Cardiac and Pulmonary Fibrosis

Aaron L. Sverdlov,Darryl A. Knight,David W. Waters,Doan TM. Ngo,Janette K. Burgess,Lucy A. Murtha,Matthew Morten,Michael J. Schuliga,Nishani S. Mabotuwana,Sean A. Hardy

Adipose-derived Stem Cells Attenuates Diabetic Osteoarthritis via Inhibition of Glycation-mediated Inflammatory Cascade

David F. Williams,Feng-Chou Tsai,Hong-Jian Wei,Joseph R. Wang,Navneet Kumar Dubey,Peter D. Wang,Sung-Hsun Yu,Yue-Hua Deng

The Prognostic Value of Serum Cytokines in Patients with Acute Ischemic Stroke

Hongxia Zhang,Kunlin Jin,Qian Li,Shaohua Yang,Siyang Lin,Wensi Huang,Xianmei Li,Xiaoli Chen,Xudong Chen

Duration and Quality of Sleep and Risk of Physical Function Impairment and Disability in Older Adults: Results from the ENRICA and ELSA Cohorts

Arthur E. Mesas,Fernando Rodríguez-Artalejo,Jose Antonio Carnicero-Carre？o,Marcela Z. Campanini

Emerging Roles of Complement Protein C1q in Neurodegeneration

Mitochondrial Creatine Kinase is Decreased in the Serum of Idiopathic Parkinson’s Disease Patients

Dongmei Wang,Guanghui Liu,Jianjun Lu,Mengqiu Pan,Qing Wang,Qiong Chen,Qun Wang,Suyue Pan,Xiao Zhou,Xiaodi Fu,Xiaomei Zhang,Xiaoxian Huang,Yafang Hu,Yan Liu,Yanhui Li,Yunqi Xu,Zhaoyu Chen

Is Dementia More Fatal Than Previously Estimated? A Population-based Prospective Cohort Study

Bong Jo Kim,Dong Woo Lee,Dong Young Lee,Jeong Lan Kim,Ji Won Han,Jin Hyeong Jhoo,Jong Bin Bae,Jong Chul Youn,Joon Hyuk Park,Jung Jae Lee,Kyung Phil Kwak,Seok Bum Lee,Seok Woo Moon,Seung-Ho Ryu,Shin Gyeom Kim,Tae Hui Kim

Chronic Kidney Disease Is Linked to Carotid Nodular Calcification, An Unstable Plaque Not Correlated to Inflammation

Alessandro Mauriello,Andrea Saggini,Arnaldo Ippoliti,Elena Bonanno,Francesca Davato,Giuseppe Santeusanio,Lucia Anemona,Manuel Scimeca,Marina Cardellini,Marta Ballanti,Massimo Federici,Nicola Di Daniele,Rossella Menghini,Sara Casella,Simone Bischetti,Valentina Rovella

Relationship between Hypothyroidism and Endometrial Cancer

Rong Zhou,Yiqin Wang

Deficiency of Yes-Associated Protein Induces Cataract in Mice

Lujun Zhou,Qing He,Tongxing Wang,Wenxia Zhou,Yuhao Gao

Novel Insights on Systemic and Brain Aging, Stroke, Amyotrophic Lateral Sclerosis, and Alzheimer’s Disease

Ashok K. Shetty,Leelavathi N. Madhu,Maheedhar Kodali,Raghavendra Upadhya

Genetic Interaction of APOE and FGF1 is Associated with Memory Impairment and Hippocampal Atrophy in Alzheimer’s Disease

Chi-Wei Huang,Chiung-Chih Chang,Hiroaki Kazui,Shih-Wei Hsu,Shu-Hua Huang,Wen-Neng Chang,Ya-Ting Chang

A Microcirculatory Theory of Aging