Constructing care cascades for active tuberculosis: A strategy for program monitoring and identifying gaps in quality of care

Kenneth H. Mayer,Madhukar Pai,Nimalan Arinaminpathy,Ramnath Subbaraman,Ruvandhi R. Nathavitharana,Srinath Satyanarayana,Vineet K. Chadha

The US Affordable Care Act: Reflections and directions at the close of a decade

Adrianna McIntyre,Zirui Song

PLOS Medicine 2018 Reviewer and Editorial Board Thank You

Trazodone use and risk of dementia: A population-based cohort study

David P. J. Osborn,Ian C. K. Wong,Joseph F. Hayes,Joseph Kim,Kenneth K. C. Man,Robert Howard,Ruth Brauer,Wallis C. Y. Lau

Correction: Expected changes in obesity after reformulation to reduce added sugars in beverages: A modeling study

Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study

Andrew R. Wood,Ashley Budu-Aggrey,Ben Brumpton,Bj？rn Olav ？svold,Carlos Celis-Morales,Ellen H. Modalsli,George Davey Smith,Gunnhild ？berge Vie,Iain B. McInnes,James T. Elder,Jess Tyrrell,Jonas Bille Nielsen,Lam C. Tsoi,Lars G. Fritsche,Lavinia Paternoster,Lyn D. Ferguson,Mari L？set,Marit Saunes,Naveed Sattar,P？l Richard Romundstad,Robin Beaumont,Samuel E. Jones,Sara J. Brown,Sarah Watkins,Stefan Siebert,Timothy M. Frayling,Tom Palmer,Wei Zhou

Setting targets for HIV/AIDS—What lessons can be learned from other disease control programmes?

David Heymann,Jamie Enoch,Mishal Khan,Osman Dar,Richard Hayes,Sophie Mathewson,Tazeem Bhatia

COSMOS-E: Guidance on conducting systematic reviews and meta-analyses of observational studies of etiology

Andrew G. Renehan,Douglas G. Altman,Jan P. Vandenbroucke,Matthias Egger,Myriam Cevallos,Olaf M. Dekkers

Health system performance for people with diabetes in 28 low- and middle-income countries: A cross-sectional study of nationally representative surveys

Andrew Stokes,Bahendeka K. Silver,Bolormaa Norov,Brice Wilfried Bicaba,Cara Ebert,Chea Stanford Wesseh,Corine Houehanou,David Guwatudde,Demetre Labadarios,Dismand Houinato,Garry Brian,Gibson B. Kagaruki,Gladwell Gathecha,Glennis Andall-Brereton,Jennifer Manne-Goehler,Joao S. Martins,Joseph Kibachio Mwangi,Justine I. Davies,Jutta Mari Adelin Jorgensen,Khem B. Karki,Kokou Agoudavi,Krishna K. Aryal,Lela Sturua,Lindiwe Tsabedze,Lindsay M. Jaacks,Maja Marcus,Maria Dorobantu,Mary T. Mayige,Mohamed Msaidie,Mongal Singh Gurung,Omar Mwalim,Pascal Bovet,Pascal Geldsetzer,Rifat Atun,Roy Wong McClure,Sarah Quesnel-Crooks,Sebastian Vollmer,Till W. B？rnighausen

A whole-health–economy approach to antimicrobial stewardship: Analysis of current models and future direction

Alison Holmes,Christianne Micallef,Fiona Sim,Monsey McLeod,Nada Atef Shebl,Raheelah Ahmad

The Ayushman Bharat Pradhan Mantri Jan Arogya Yojana and the path to universal health coverage in India: Overcoming the challenges of stewardship and governance

Anadi Gupt,Blake J. Angell,Shankar Prinja,Stephen Jan,Vivekanand Jha

Measles vaccination: A matter of confidence and commitment

Richard Turner,on behalf of the PLOS Medicine Editors

Advances in clinical trial design for development of new TB treatments: A call for innovation

Christian Lienhardt,Payam Nahid

Keeping phase III tuberculosis trials relevant: Adapting to a rapidly changing landscape

Andrew J. Nunn,Carole D. Mitnick,Christian Lienhardt,James D. Neaton,Patrick P. J. Phillips,Payam Nahid

Correction: A new aging measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: A cohort study

The association between heatwaves and risk of hospitalization in Brazil: A nationwide time series study between 2000 and 2015

Kejia Hu,Michael J. Abramson,Micheline S. Z. S. Coelho,Paulo H. N. Saldiva,Qi Zhao,Rachel R. Huxley,Shanshan Li,Yuming Guo

Patterns of joint involvement in juvenile idiopathic arthritis and prediction of disease course: A prospective study with multilayer non-negative matrix factorization

Alan M. Rosenberg,Florence A. Aeschlimann,Mira van Veenendaal,Quaid Morris,Rae S. M. Yeung,Roberta A. Berard,Simon W. M. Eng,on behalf of the ReACCh-Out Research Consortium

National policies and care provision in pregnancy and childbirth for twins in Eastern and Southern Africa: A mixed-methods multi-country study

Agnes Binagwaho,Andrea B. Pembe,Bellington Vwalika,Claudia Hanson,Elsa Jacinto,George K. Chilinda,Kateri B. Donahoe,Lenka Benova,Muchabayiwa F. Gidiri,Peter Waiswa,Sikolia Z. Wanyonyi,Stephen Munjanja

Community-, facility-, and individual-level outcomes of a district mental healthcare plan in a low-resource setting in Nepal: A population-based evaluation

Brandon A. Kohrt,Crick Lund,Emily C. Garman,Ivan H. Komproe,Mark J. D. Jordans,Mary De Silva,Nagendra P. Luitel,Sujit D. Rathod,Vikram Patel

A reduced-carbohydrate and lactose-free formulation for stabilization among hospitalized children with severe acute malnutrition: A double-blind, randomized controlled trial

André Briend,Anneke C. Muller Kobold,Benjamin Allubha,Betty Owor,Celine Bourdon,Christian J. Versloot,Deborah A. van den Brink,Emmanuel Chimwezi,Fauzat Hamid,Greg Fegan,Isabel Potani,James A. Berkley,Johnstone Thitiri,Laura Mwalekwa,Marjon Feenstra,Marko Kerac,Moses Ngari,Neema Mturi,Patrick F. van Rheenen,Rehema Ali,Robert H. J. Bandsma,Rosalie H. Bartels,Victor Bandika,Wieger Voskuijl

Antenatal corticosteroid therapy (ACT) and size at birth: A population-based analysis using the Finnish Medical Birth Register

Alina Rodriguez,Anohki Ali Khan,Marjo-Riitta J？rvelin,Mika Gissler,Rufus Cartwright,Yingbo Wang

The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in Southeast Asia: A cluster randomised trial

Arjen M. Dondorp,Atthanee Jeeyapant,Benchawan Vihokhern,Benoit Malleret,Bipin Adhikari,Borimas Hanboonkunupakarn,Carl Onsj？,Chan Davoeung,Chea Nguon,Cholrawee Promnarate,Christopher Pell,Daniel M. Parker,Dao Van Hue,Do Hung Son,Francois H. Nosten,Frank Cobelens,Frank Smithuis,Georges Snounou,Gisela Henriques,Guy E. Thwaites,Huy Rekol,Huynh Hong Quang,Jacher Wiladphaingern,Jeremy Chalk,Jordi Landier,Julie A. Simpson,Kesinee Chotivanich,Khin Maung Lwin,Koukeo Phommasone,Krittaya Patumrat,Ladda Kajeechiwa,Laurent Rénia,Le Thanh Dong,Lilly Keereecharoen,Lisa J. White,Lorenz von Seidlein,Mallika Imwong,Martin P. Grobusch,Mavuto Mukaka,May Myo Thwin,Mayfong Mayxay,Mehul Dhorda,Nguyen Thanh Tien,Nguyen Thi Kim Tuyen,Nguyen Tuong-Vy,Nicholas J. White,Nicholas P. J. Day,Nils Kaehler,Olivo Miotto,Panom Phongmany,Pasathorn Sirithiranont,Paul N. Newton,Phaik Yeong Cheah,Pham Nguyen Huong-Thu,Pimnara Peerawaranun,Podjanee Jittmala,Pratap Singhasivanon,Preyanan Suangkanarat,Ricardo Aguas,Rob W. van der Pluijm,Rupam Tripura,Sasithon Pukrittayakamee,Stephane Proux,Sue J. Lee,Suphak Nosten,Thomas J. Peto,Thuy-Nhien Nguyen,Tiengkham Pongvongsa,Tran Tinh Hien,Truong Le Phuc-Nhi,Vincent Corbel,Xin Hui Chan,Yoel Lubell

Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis

Adri？tte J. J. M. Oostvogels,Agnieszka Pac,Alet Wijga,Ana C. Santos,Andrea von Berg,Anna Bergstr？m,Anne M. Karvonen,Anne-Marie Nybo Andersen,Barbara Heude,Bernadeta Patro Golab,Berthold Koletzko,Camilla S. Morgen,Camilla Stoltenberg,Carel Thijs,Carol Ní Chaoimh,Costanza Pizzi,Cécile Chevrier,Daniel Hryhorczuk,Daniela Porta,Davide Gori,Debbie A. Lawlor,Deirdre Murray,Eleni Papadopoulou,Elisabeth Thiering,Ellen A. Nohr,Ellis Voerman,Emily Oken,Eva Corpeleijn,Ferran Ballester,Fionnuala M. McAuliffe,Francesco Forastiere,George Moschonis,George P. Chrousos,Graham Devereux,Hanna Lagstr？m,Hazel Inskip,Henrique Barros,Irina Lehmann,Irva Hertz-Picciotto,Jane West,Johanna M？kel？,John Mehegan,John Wright,Juha Pekkanen,Keith M. Godfrey,Kinga Polanska,Leanne K. Küpers,Leda Chatzi,Lenie van Rossem,Lorenzo Richiardi,Louise C. Kenny,Luca Ronfani,Maria Pia Fantini,Marie Standl,Marie-Aline Charles,Martine Vrijheid,Maties Torrent,Merete Eggesb？,Monique Mommers,Nathalie Costet,Nina Iszatt,Oleksandr Zvinchuk,Per Magnus,Pilar Amiano,Rae-Chi Huang,Renata Majewska,Romy Gaillard,Sandra Ekstr？m,Sara Farchi,Sarah Crozier,Sheila W. McDonald,Sheryl L. Rifas-Shiman,Steve Turner,Susana Santos,Suzanne C. Tough,Tanja G. M. Vrijkotte,Thorkild I. A. S？rensen,Tomas Trnovec,Trevor A. Mori,Vagelis Georgiu,Veit Grote,Vincent W. V. Jaddoe,Wojciech Hanke,Yannis Manios

Lifetime risk and multimorbidity of non-communicable diseases and disease-free life expectancy in the general population: A population-based cohort study

Albert Hofman,Alis Heshmatollah,Banafsheh Arshi,Bruno H. Ch. Stricker,Daniel Bos,Emmely W. de Roos,Guy G. O. Brusselle,Kimberly D. van der Willik,Lana Fani,Lies Lahousse,M. Arfan Ikram,M. Kamran Ikram,Maarten J. G. Leening,Maryam Kavousi,Peter J. Koudstaal,Rikje Ruiter,Silvan Licher

The effect of a programme to improve men’s sedentary time and physical activity: The European Fans in Training (EuroFIT) randomised controlled trial

Alex McConnachie,Annie S. Anderson,Christopher Bunn,Cindy M. Gray,David W. Loudon,Douglas J. Maxwell,Eivind Andersen,Femke van Nassau,Glyn C. Roberts,Hidde P. van der Ploeg,Hugo V. Pereira,Irene van de Glind,Jason M. R. Gill,John Rooksby,Judith Bosmans,Judith G. M. Jelsma,Kate Hunt,Lisa Macaulay,Maria Nijhuis-van der Sanden,Marit S？rensen,Marlene N. Silva,Matthew Philpott,Nanette Mutrie,Naveed Sattar,Nicolas Lemyre,Paula McSkimming,Pedro J. Teixeira,Sally Wyke,Sharon Kean,Shaun Treweek,Spyros Kolovos,Theo van Achterberg,Willem van Mechelen,？ystein B. R？ynesdal

Long-term outcomes of an educational intervention to reduce antibiotic prescribing for childhood upper respiratory tract infections in rural China: Follow-up of a cluster-randomised controlled trial

James N. Newell,Jia Yin,John D. Walley,Joseph P. Hicks,Jun Zeng,Mei Lin,Qiang Sun,Rebecca King,Ross E. G. Upshur,Xiaolin Wei,Yan Guo,Zhitong Zhang

Incidence of eclampsia and related complications across 10 low- and middle-resource geographical regions: Secondary analysis of a cluster randomised controlled trial

Andrew H. Shennan,Elodie Lawley,Jane Sandall,Lucy C. Chappell,Muchabayiwa Francis Gidiri,Nicola Vousden,Paul T. Seed,Shivaprasad Goudar,on behalf of the CRADLE Trial Collaborative Group

Correction: Evaluating strategies for control of tuberculosis in prisons and prevention of spillover into communities: An observational and modeling study from Brazil

Correction: The effect of a programme to improve men's sedentary time and physical activity: The European Fans in Training (EuroFIT) randomised controlled trial

Controlling latent TB tuberculosis infection in high-burden countries: A neglected strategy to end TB

Gavin J. Churchyard,Sue Swindells

Seasonal malaria chemoprevention combined with community case management of malaria in children under 10 years of age, over 5 months, in south-east Senegal: A cluster-randomised trial

Amadou Seck,Babacar Faye,Colin Sutherland,Jean Louis A. Ndiaye,Khalid Beshir,Maguette Ndiaye,Mamadou S. Ba,Oumar Gaye,Pape Moussa Thior,Paul Milligan,Roger Tine,Sharanjeet Atwal,Youssoupha Ndiaye

Comparative effectiveness of generic and brand-name medication use: A database study of US health insurance claims

Aaron S. Kesselheim,Ameet Sarpatwari,James R. Rogers,John G. Connolly,Joshua J. Gagne,Joyce Lii,Justin Bohn,Michael A. Fischer,Nazleen F. Khan,Rishi J. Desai,Saeid Raofi,Sara Dejene,Sarah K. Dutcher

Independent and combined effects of improved water, sanitation, and hygiene (WASH) and improved complementary feeding on early neurodevelopment among children born to HIV-negative mothers in rural Zimbabwe: Substudy of a cluster-randomized trial

Ancikaria Chigumira,Andrew J. Prendergast,Cynthia M. Chasokela,Florence D. Majo,Goldberg T. Mangwadu,Gwendoline Kandawasvika,Jaya Chandna,Jean H. Humphrey,Lawrence H. Moulton,Mduduzi N. N. Mbuya,Melissa J. Gladstone,Naume V. Tavengwa,Rebecca J. Stoltzfus,Robert Ntozini,for the SHINE Trial Team

Community health workers to improve uptake of maternal healthcare services: A cluster-randomized pragmatic trial in Dar es Salaam, Tanzania

Anna Mia Ekstr？m,Charles Kilewo,David Sando,Dawn Foster,Donna Spiegelman,Elysia Larson,Eric Mboggo,Ester Mungure,Guerino Chalamilla,Helga Naburi,Hellen Siril,Irene Andrew Lema,Lameck Machumi,Lucy Magesa,Mary Mwanyika-Sando,Nan Li,Nzovu Ulenga,Pascal Geldsetzer,Phares Mujinja,Till B？rnighausen,Wafaie Fawzi

Potential effectiveness of prophylactic HPV immunization for men who have sex with men in the Netherlands: A multi-model approach

Johannes A. Bogaards,Maarten F. Schim van der Loeff,Maria Xiridou,Sofie H. Mooij

Age distribution, trends, and forecasts of under-5 mortality in 31 sub-Saharan African countries: A modeling study

Eran Bendavid,Iván Mejía-Guevara,Nan Li,Shripad Tuljapurkar,Wenyun Zuo

Individual prognosis at diagnosis in nonmetastatic prostate cancer: Development and external validation of the PREDICT Prostate multivariable model

David C. Greenberg,David R. Thurtle,Hong H. Huang,Lui S. Lee,Paul D. Pharoah,Vincent J. Gnanapragasam

Cost-effectiveness of financial incentives for improving diet and health through Medicare and Medicaid: A microsimulation study

Dariush Mozaffarian,Junxiu Liu,Parke E. Wilde,Renata Micha,Shafika Abrahams-Gessel,Stephen Sy,Thiago de Souza Veiga Jardim,Thomas A. Gaziano,Yue Huang,Yujin Lee

The association between Zika virus infection and microcephaly in Brazil 2015–2017: An observational analysis of over 4 million births

Aaron Osgood-Zimmerman,Aglaêr A. da Nóbrega,Ali H. Mokdad,Antony Stevens,Bruno Zoca de Oliveira,Christopher J. L. Murray,Fatima Marinho,Isaac I. Bogoch,José M. de Lima, Jr.,Livia C. V. Frutuoso,Nicholas J. Kassebaum,Oliver J. Brady,Philippe Mayaud,Robert C. Reiner, Jr.,Roberto C. R. Lecca,Sarah E. Ray,Simon I. Hay,Thomas Jaenisch,Valdelaine E. M. de Araújo

Addressing critical needs in the fight to end tuberculosis with innovative tools and strategies

Claudia M. Denkinger,Mark Hatherill,Richard E. Chaisson

Tuberculosis vaccines: Rising opportunities

Jeremy Farrar,Johan Vekemans,Katherine L. O’Brien

Tuberculosis drugs’ distribution and emergence of resistance in patient’s lung lesions: A mechanistic model and tool for regimen and dose optimization

Clifton E. Barry, III,Hyeeun Bang,Laura E. Via,Matthew Zimmerman,Myungsun Lee,Natasha Strydom,Radojka M. Savic,Seokyong Eum,Sneha V. Gupta,TaeSun Shim,Véronique Dartois,William S. Fox

Effects of repeat prenatal corticosteroids given to women at risk of preterm birth: An individual participant data meta-analysis

Caroline A. Crowther,Cindy McEvoy,Debra A. Guinn,Elizabeth A. Thom,Elizabeth V. Asztalos,Fariba Aghajafari,Kellie E. Murphy,Kimberley Maurel,Lex W. Doyle,Lisa Askie,Men-Jean Lee,Merryn Voysey,Mikko Hallman,Outi M. Peltoniemi,Peter Brocklehurst,Philippa F. Middleton,Pollyanna Hardy,Premasish Mazumder,Ronald J. Wapner,Sasha Zhang,Sourabh Dutta,Tanya K. Martlow,Thomas J. Garite,the PRECISE Group

Host-response-based gene signatures for tuberculosis diagnosis: A systematic comparison of 16 signatures

Hayley Warsinske,Purvesh Khatri,Rohit Vashisht

Lay health supporters aided by mobile text messaging to improve adherence, symptoms, and functioning among people with schizophrenia in a resource-poor community in rural China (LEAN): A randomized controlled trial

Dong (Roman) Xu,Eric D. Caine,Hua He,James P. Hughes,Jane Simoni,Juan Nie,Meijuan Lin,Shuiyuan Xiao,Stephen Gloyd,Wenjie Gong,Wenjun He,Yeqing Yuan

Pharmacokinetics, optimal dosing, and safety of linezolid in children with multidrug-resistant tuberculosis: Combined data from two prospective observational studies

Anneke C. Hesseling,Anthony J. Garcia-Prats,H. Simon Schaaf,Heather R. Draper,Jana Winckler,Lubbe Wiesner,Maria Garcia-Cremades,Rada M. Savic

Evaluation of a social protection policy on tuberculosis treatment outcomes: A prospective cohort study

Cristina Chirico,Fernando Rubinstein,Karen Klein,Luz Gibbons,Maria Paula Bernachea,Sarah Irribarren

Whole-genome and targeted sequencing of drug-resistant Mycobacterium tuberculosis on the iSeq100 and MiSeq: A performance, ease-of-use, and cost evaluation

Amanda G. Young,Anita Suresh,Aurélien Mace,Claudia M. Denkinger,Darrin Lemmer,David M. Engelthaler,Donald G. Catanzaro,Haifa Mshaiel,Jonathan Hetzel,Marva Seifert,Rebecca E. Colman,Timothy C. Rodwell

Diagnostic value of the urine lipoarabinomannan assay in HIV-positive, ambulatory patients with CD4 below 200 cells/μl in 2 low-resource settings: A prospective observational study

Alex Telnov,Elisabeth Sanchez-Padilla,Elisabeth Szumilin,Helena Huerga,Isabel Amoros,Ivan Manhi？a,Kuzani Mbendera,Loide Cossa,Lucas Molfino,Mathieu Bastard,Sekai Chenai Mathabire Rucker

Changes in rapid HIV treatment initiation after national “treat all” policy adoption in 6 sub-Saharan African countries: Regression discontinuity analysis

Constantin T. Yiannoutsos,Denis Nash,Elizabeth Zaniewski,Ellen Brazier,Fred Nalugoda,Grace Liu,Jean d’Amour Sinayobye,Kara Wools-Kaloustian,Mark Urassa,Mary-Ann Davies,Michael Vinikoor,Monique van Lettow,Nanina Anderegg,Nathan Ford,Olga Tymejczyk,Peter F. Rebeiro,on behalf of the IeDEA consortium