The endonuclease APE1 processes miR-92b formation, thereby regulating expression of the tumor suppressor LDLR in cervical cancer cells

Guiqian Zhang,Ya Xu,Yi Sun,Yun Feng

Identification of CSPG4 as a promising target for translational combinatorial approaches in osteosarcoma

Davide Giacobino,Emanuela Morello,Federica Cavallo,Federica Riccardo,Federica Sammartano,Francesca Gattino,Lidia Tarone,Maddalena Arigoni,Marina Martano,Paolo Buracco,Raffaella De Maria,Selina Iussich,Soldano Ferrone

Third-line systemic treatment in advanced/metastatic gastric cancer: a comprehensive review

Ka-on Lam,Lai-wan Dora Kwong,Tsz-him So,Victor Ho-fun Lee,Wing-lok Chan

Molecular targeted therapy of BRAF-mutant colorectal cancer

Ali Chamseddine,Antoine Hollebecque,Cristina Smolenschi,David Malka,Emmanuelle Samallin,Maximiliano Gelli,Michel Ducreux,Peggy Dartigues,Pierre Laurent-Puig,Valérie Boige

Results from a meta-analysis of immune checkpoint inhibitors in first-line renal cancer patients: does PD-L1 matter?

Enrico Mini,Gabriella Nesi,Giandomenico Roviello,Silvia Paola Corona

TIMP-3 as a therapeutic target for cancer

Chiao-Wen Lin,Chun-Wen Su,Shun-Fa Yang,Wei-En Yang

Pilot study of bevacizumab in combination with docetaxel and cyclophosphamide as adjuvant treatment for patients with early stage HER-2 negative breast cancer, including analysis of candidate circulating markers of cardiac toxicity: ICORG 08–10 trial

Alex J. Eustace,Alexandra Canonici,Alice C. O’Farrell,Andres Hernando,Annette T. Byrne,Ashwini Maratha,Bonnie Ky,Brian Moulton,David W. Murray,Denis M. Collins,Dimitrios Tryfonopoulos,Enda McDermott,Giuseppe Gullo,Gregory Leonard,Imelda Parker,Janice Walshe,John Crown,John McCaffrey,Kathleen Scott,Liam Grogan,Maccon Keane,Mairin Rafferty,Michael J. Kennedy,Michael J. Martin,Miriam O’Connor,Norma O’Donovan,Oscar Breathhnach,Patrick Dicker,Paul Donnellan,Paula M. Calvert,Rajnish Gupta,Verena Murphy,William M. Gallagher

Immunotherapy for hepatocellular carcinoma: recent advances and future perspectives

Geoffrey W McCaughan,Jiansong Ji,Jin-Yu Sun,Ken Liu,Minjiang Chen,Weiqi Xu,Xiao-Jie Lu

The risk of liver cancer in autoimmune liver diseases

Ana Lleo,Massimo Colombo,Rodrigo Liberal,Ynto S. de Boer

Association between circulating tumor cells and peripheral blood monocytes in metastatic breast cancer

Antonio Giordano,Emanuela Scarpi,James M. Reuben,Mario Giuliano,Massimo Cristofanilli,Michal Mego,Naoto T. Ueno,Ricardo H. Alvarez,Ugo De Giorgi,Vicente Valero

Targeting CDK9 and MCL-1 by a new CDK9/p-TEFb inhibitor with and without 5-fluorouracil in esophageal adenocarcinoma

Alicia Mejia,Anuj Verma,Arlene M. Correa,Barbara Mino,Dipen M. Maru,Jaffer A. Ajani,Jaime Rodriguez-Canales,Luisa Maren Solis,Mariela Blum,Omkara Veeranki,Rashmi Dokey,Riham Kathkuda,Scott Kopetz,Steven H. Lin,Sunil Krishnan,Viren Patel,Wayne L. Hofstetter,Zhimin Tong

High blood sugar levels but not diabetes mellitus significantly enhance oxaliplatin chemoresistance in patients with stage III colorectal cancer receiving adjuvant FOLFOX6 chemotherapy

Ching-Wen Huang,Hsiang-Lin Tsai,I-Ping Yang,Jaw-Yuan Wang,Se-fen Chang,Tsung-Kun Chang,Wei-Chih Su,Yung-Sung Yeh,Zhi-Feng Miao

Karonudib is a promising anticancer therapy in hepatocellular carcinoma

Azita Rasti,Camilla Gokturk,Helge Gad,Jianjun Zhang,Kang He,Kumar Sanjiv,Mingxuan Feng,Qiang Xia,Therese Pham,Thomas Helleday,Ulrika Warpman Berglund,Xiangwei Hua,Yunjin Zang,Zhenjun Zhao

Neoadjuvant therapy of locally/regionally advanced melanoma

Ahmad A. Tarhini,Arjun Khunger,Keith A. Delman,Michael Lowe,Mohammad K. Khan,Zachary S. Buchwald

Opportunities for cannabis in supportive care in cancer

Amber S. Kleckner,Charles S. Kamen,Gary R. Morrow,Ian R. Kleckner,Luke J. Peppone,Michelle C. Janelsins,Mohamedtaki A. Tejani

Effectiveness of drug-eluting bead transarterial chemoembolization versus conventional transarterial chemoembolization for small hepatocellular carcinoma in Child-Pugh class A patients

Hwan Jun Jae,Hyo-Cheol Kim,In Joon Lee,Jeong-Hoon Lee,Jin Wook Chung,Jung-Hwan Yoon,Myungsu Lee,Saebeom Hur,Yong Hu Yin,Yoon Jun Kim,Yun Bin Lee

Late-line treatment in metastatic gastric cancer: today and tomorrow

Elizabeth C. Smyth,Markus Moehler

The evolving immuno-oncology landscape in advanced lung cancer: first-line treatment of non-small cell lung cancer

Gloria Chan,Jia Li Low,Robert J. Walsh,Ross A. Soo,Yvonne Ang

Real-world efficacy and safety of liposomal irinotecan plus fluorouracil/leucovorin in patients with metastatic pancreatic adenocarcinoma: a study by the Korean Cancer Study Group

Baek-Yeol Ryoo,Changhoon Yoo,Do-Youn Oh,Guk Jin Lee,Hong Jae Chon,Hye Jin Choi,Hyeon-Su Im,Ilhwan Kim,Joo Hoon Kim,Joon Oh Park,Kyu-pyo Kim,Kyung-Hun Lee,Myoungjoo Kang,Seung Tae Kim,Sung Yong Oh,Younak Choi

Corrigendum to Real-world comparative effectiveness of nab-paclitaxel plus gemcitabine versus FOLFIRINOX in advanced pancreatic cancer: a systematic review

Clinically relevant drug interactions with multikinase inhibitors: a review

Frank G. A. Jansman,G. D. Marijn Veerman,Koen G. A. M. Hussaarts,Roelof W. F. van Leeuwen,Ron H. J. Mathijssen,Teun van Gelder

Predicting mortality and adverse events in patients with advanced pancreatic cancer treated with palliative gemcitabine-based chemotherapy in a multicentre phase III randomized clinical trial: the APC-SAKK risk scores

Bengt Glimelius,Daniel Dietrich,Gy？rgy Bodoky,Peter Brauchli,Piera Gargiulo,Richard Herrmann,Sandro Pignata,Simona Berardi,Thomas Ruhstaller,Werner Scheithauer

Academic oncology clinicians’ understanding of biosimilars and information needed before prescribing

Jeffrey M. Switchenko,John W. Cook,Margie D. Dixon,Megan K. McGrath,R. Donald Harvey,Rebecca D. Pentz

The impact of the Glasgow Prognostic Score on survival in second-line chemotherapy for metastatic colorectal cancer patients with BRAF V600E mutation

Hiroya Taniguchi,Kazunori Honda,Kei Muro,Keiji Sugiyama,Masahiro Tajika,Masashi Ando,Seiichiro Mitani,Shigenori Kadowaki,Takashi Ura,Toshiki Masuishi,Yasushi Yatabe,Yukiya Narita

D-methionine alleviates cisplatin-induced mucositis by restoring the gut microbiota structure and improving intestinal inflammation

Cheng-Hsi Wu,Chu-Chyn Ou,Jiuan-Miaw Liao,Jiunn-Liang Ko,Li-Yu Chang,Ling-Hui Lee,Meei-Yn Lin,Shiang-Suo Huang

Do all patients with advanced N-stage nasopharyngeal carcinoma benefit from the addition of induction chemotherapy to concurrent chemoradiotherapy?

Fan Zhang,Guan-Qun Zhou,Huai-Li Zhou,Ji-Jin Yao,Jun Ma,Li Lin,Qiao-Dan Liu,Si-Yang Wang,Wang-Jian Zhang,Wayne R. Lawrence,Xiao-Feng Pei,Ya-Nan Jin,Ying Sun,Zhi-Gang Liu

HER2-positive breast cancer: new therapeutic frontiers and overcoming resistance

Sara M. Tolaney,Sonia Pernas

Clinical relevance of circulating molecules in cancer: focus on gastrointestinal stromal tumors

César Serrano,Giulia Sammarini,Gloria Ravegnini,Margherita Nannini,Maria A. Pantaleo,Patrizia Hrelia,Sabrina Angelini

Prognostic value of ALDH1 and Nestin in advanced cancer: a systematic meta-analysis with trial sequential analysis

Fenggang Hou,Hongjia Li,Kunhe Shi,Qi Shi,Shanshan Liu,Susu Han,Tao Huang？,Wei Yang,Wen Li,Xing Wu,Xiyu Wang

Post-neoadjuvant treatment and the management of residual disease in breast cancer: state of the art and perspectives

Debora Fumagalli,Evandro de Azambuja,Martine Piccart,Matteo Lambertini,Noam Pondé,Rafael Caparica

Combined targeted therapy and immunotherapy in melanoma: a review of the impact on the tumor microenvironment and outcomes of early clinical trials

Meredith S. Pelster,Rodabe N. Amaria

First-line afatinib for the treatment of EGFR mutation-positive non-small-cell lung cancer in the ‘real-world’ clinical setting

Darren Wan-Teck Lim,Isamu Okamoto,James Chih-Hsin Yang,Keunchil Park

Overexpression of long noncoding RNA LINC01419 in esophageal squamous cell carcinoma and its relation to the sensitivity to 5-fluorouracil by mediating GSTP1 methylation

Chen Chen,Guo-Dong Qiu,Jian-Liang Chen,Jie-Ting Zheng,Shu-Yao Zhang,Yu-Qi She,Yun Chen,Yun-Sheng Qin,Zhi-Xiong Lin,Zhong-Lin Chen

Adjuvant chemotherapy improves prognosis of resectable stage IV colorectal cancer: a comparative study using inverse probability of treatment weighting

Hiroaki Nozawa,Hirofumi Sonoda,Hirotoshi Takiyama,Jun Nakajima,Kazuhito Sasaki,Kazushige Kawai,Keisuke Hata,Kiyoshi Hasegawa,Koji Murono,Manabu Kaneko,Shigenobu Emoto,Takeshi Nishikawa,Toshiaki Tanaka

Comparison of toxicity and effectiveness between fixed-dose and body surface area-based dose capecitabine

Caroline M.P.W. Mandigers,Didier Meulendijks,Esther Oomen-de Hoop,Esther van Meerten,Femke M. de Man,G.D. Marijn Veerman,Jan H.M. Schellens,Maarten J. Deenen,Marcel Soesan,Ron H.J. Mathijssen,Teun van Gelder

Palbociclib and ribociclib in breast cancer: consensus workshop on the management of concomitant medication

Ada Ruiz,Ainhara Lahuerta,Analía Azaro,Anastasi Martín,Antonia Perelló,Carolina Valdivia,Cristina Hernando,Encarna Adrover,Faten Ahmad,Helena Masanas,Isabel Ruíz,Joaquín Gavilá,Josep Lluís Parra,Juan Aguilar,Julián Palomino-Doza,Lorena de la Pe？a,Maria Valls-Margarit,Maria Vidal,María Alcalde,Meritxell Bellet,Miguel Gil,Miguel àngel Seguí,Pamela Céliz,Pilar Zamora,Rafael Villanueva,Santiago Escrivá-de-Romaní,Victoria Reyes,Xavier Gonzàlez

Patterns of treatment and outcome with 500-mg fulvestrant in postmenopausal women with hormone receptor-positive/HER2-negative metastatic breast cancer: a real-life multicenter Italian experience

Anna Gambaro,Antonella Ferzi,Antonio Bernardo,Barbara Tagliaferri,Cristina Teragni,Erica Quaquarini,Federico Sottotetti,Francesco Serra,Luca Licata,Pietro Lapidari,Raffaella Palumbo

New frontiers in the medical management of gastrointestinal stromal tumours

Alessandro Mazzocca,Andrea Napolitano,Bruno Vincenzi,Daniele Santini,Giuseppe Tonini,Marianna Silletta,Mariella Spalato Ceruso

Adjuvant therapy for pancreatic body or tail adenocarcinoma: a study of the National Cancer Database

Andrew Hanna,Cherif Boutros,Max Seaton,Nader Hanna

Proteomic analysis of gemcitabine-resistant pancreatic cancer cells reveals that microtubule-associated protein 2 upregulation associates with taxane treatment

Bart Kok,Btissame El Hassouni,Connie R. Jimenez,Elisa Giovannetti,Geert Kazemier,Hanneke W.M. van Laarhoven,Kenneth P. Olive,Maarten F. Bijlsma,Niccola Funel,Sander R. Piersma,Tessa Ya Sung Le Large,Thang V. Pham

Gelsolin-like actin-capping protein has prognostic value and promotes tumorigenesis and epithelial-mesenchymal transition via the Hippo signaling pathway in human bladder cancer

Cai Zhiming,Chen Miao,Chen Yacun,Guan Xinyuan,He Anbang,Liao Xinhui,Liu Yuchen,Lyu Zhaojie,Mei Hongbing,Wang Feng,Wu Peipei,Wu Shayi,Zhang Meng

Monitoring blood biomarkers to predict nivolumab effectiveness in NSCLC patients

Alessandro Perez,Angela Listì,Antonio Galvano,Antonio Russo,Francesco Passiglia,Giuseppe Gallina,Hector Soto Parra,Lorena Incorvaia,Marta Castiglia,Salvatore Mazzarisi,Sergio Rizzo,Valentina Calò,Viviana Bazan

Overcoming platinum-acquired resistance in ovarian cancer patient-derived xenografts

Francesca Falcetta,Francesca Ricci,Giovanna Damia,Laura Brunelli,Maddalena Fratelli,Martina Verza,Robert Fruscio,Roberta Affatato,Roberta Pastorelli,Rosaria Chilà,Stefano Indraccolo

Intensive first-line FIr-C/FOx-C association of triplet chemotherapy plus cetuximab in RAS wild-type metastatic colorectal cancer patients: preliminary phase II data and prediction of individual limiting toxicity syndromes by pharmacogenomic biomarkers

Antonella Dal Mas,Enrico Ricevuto,Eugenio Ciacco,Francesco Pepe,Gemma Bruera,Giancarlo Troncone,Giuseppe Calvisi,Maurizio Simmaco,Silvia Massacese,Umberto Malapelle

Harnessing immunotherapy for liver recipients with hepatocellular carcinoma: a review from a transplant oncology perspective

Cheng-Maw Ho,Hui-Ling Chen,Po-Huang Lee,Rey-Heng Hu

FAM84B promotes prostate tumorigenesis through a network alteration

Anil Kapoor,Damu Tang,Fengxiang Wei,Huixiang Yang,Kuncheng Zhao,Lizhi He,Wenjuan Mei,Xiaozeng Lin,Yan Gu,Yanzhi Jiang

LKB1 and YAP phosphorylation play important roles in Celastrol-induced β-catenin degradation in colorectal cancer

Chenfei Hu,Cuiqi Zhou,Guanghui Hu,Hongxia Zhu,Kai Ma,Lechuang Chen,Mei Liu,Ningzhi Xu,Qing Xu,Shuren Wang,Yu Wang,Zhuo Li

Pressurized intraperitoneal aerosol chemotherapy with low-dose cisplatin and doxorubicin (PIPAC C/D) in patients with gastric cancer and peritoneal metastasis: a phase II study

Alfred K？nigsrainer,Christoph Meisner,Dirk Strumberg,Florian Struller,Frank-Jürgen Weinreich,Imma Fischer,Marc A. Reymond,Marios K. Kokkalis,Philipp Horvath,Wiebke Solass

Cotargeting Plk1 and androgen receptor enhances the therapeutic sensitivity of paclitaxel-resistant prostate cancer

Hyungshin Yim,Sang-Uk Woo,Sol-Bi Shin

Therapeutic effects of the novel Leucyl-tRNA synthetase inhibitor BC-LI-0186 in non-small cell lung cancer

Arum Kim,Chulho Lee,Eun Young Kim,Gyoonhee Han,Hee Chan Yoo,Jin Gu Lee,Jung Min Han,Jung Mo Lee,Kibum Kim,Minji Lee,Yoon Soo Chang