全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用：99美元
投递稿件

为什么选择我们？ >>
- 开源期刊
- 同行审议
- 快速出刊
- 终身存储
- 免费检索
- 免费推广
- 更多...
- 搜索引擎

Journal of Enzyme Inhibition and Medicinal Chemistry

ISSN Print: 1475-6366

ISSN Online:

主页: https://www.tandfonline.com/toc/ienz/current

分享:




Go

Conformational restriction of a type II FMS inhibitor leading to discovery of 5-methyl-N-(2-aryl-1H-benzo[d]imidazo-5-yl)isoxazole-4-carboxamide analogues as selective FLT3 inhibitors

Daseul Im,Hyungwoo Moon,Jingwoong Kim,Jung-Mi Hah,Miyoung Jang,Youri Oh

Synthesis, cytotoxicities, and carbonic anhydrase inhibition potential of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones

Claudiu T. Supuran,Feyza Sena Erdal,Halise Inci Gul,Hiroshi Sakagami,Ilhami Gulcin,Serkan Levent,Sinan Bilginer

Design and application of oral colon administration system

Gangliang Huang,Hao Cheng,Shiyu Huang

An overview of carbonic anhydrases and membrane channels of synoviocytes in inflamed joints

Jeong Hee Hong,Min Jeong Ji

Exosomes in head and neck cancer. Updating and revisiting

Abel García García,Andrés Blanco Carrión,Manuel Somoza Martín,Mario Pérez Sayans,Mercedes Gallas Torreira,Pilar Gándara Vila,Samuel Rodríguez Zorrilla

Novel 4-arylaminoquinazolines bearing N,N-diethyl(aminoethyl)amino moiety with antitumour activity as EGFRwt-TK inhibitor

Baolin Li,Li Chen,Li Gao,Xiabing Li,Yaling Zhang,Yaping Yan,Yunxia Hao

Activation of α-, β-, γ- δ-, ζ- and η- class of carbonic anhydrases with amines and amino acids: a review

Claudiu T. Supuran,Suleyman Akocak

Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies

Aless,Alessio Nocentini,Ciro Milite,Claudiu T. Supuran,Elisabetta Barresi,Ettore Novellino,Federico Da Settimo,Giorgio Amendola,Sabrina Castellano,Sabrina Taliani,Silvia Bua,ra Cipriano,ra Feoli,ro Cosconati

Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold

Andrea Angeli,Atilla Akdemir,Barbara De Filippis,Celeste De Monte,Claudiu T. Supuran,Cristina Maccallini,Daniela Secci,Giulia Rotondi,Paolo Guglielmi,Roberto Cirilli,Rosa Amoroso,Simone Carradori

Design, synthesis and biological evaluation of N-substituted α-hydroxyimides and 1,2,3-oxathiazolidine-4-one-2,2-dioxides with anticonvulsant activity

Andrea V. Enrique,Laureano L. Sabatier,Luciana Gavernet,María L. Sbaraglini,Pablo H. Palestro,Pedro Martín,Valentina Pastore

Discovery of new butyrylcholinesterase inhibitors via structure-based virtual screening

Mohammad A. Ghattas,Noor Atatreh,Sara Al Rawashdah,Sawsan M. Abuhamdah,Shaikha S. Al Neyadi

New peptide derived antimalaria and antimicrobial agents bearing sulphonamide moiety

D. I. Ugwu,D. I. Ugwuja,R. Soni,S. N. Okafor,S. S. Soman,U. C. Okoro

Synthesis of substituted 15β-alkoxy estrone derivatives and their cofactor-dependent inhibitory effect on 17β-HSD1

Anita Kiss,Bianka Edina Herman,Erzsébet Mernyák,Gyula Schneider,János W？lfling,Mihály Szécsi

The carbonic anhydrase IX inhibitor SLC-0111 sensitises cancer cells to conventional chemotherapy

Anna Laurenzana,Claudiu T. Supuran,Elena Andreucci,Fabrizio Carta,Francesca Bianchini,Jessica Ruzzolini,Lido Calorini,Silvia Peppicelli

Computer-aided molecular design of pyrazolotriazines targeting glycogen synthase kinase 3

Ana Martinez,Concepción Pérez,Daniel I. Perez,E. Laura Moyano,Loreto Martinez-Gonzalez,M. Lourdes Sciú,Nuria E. Campillo,Rocio Benitez,Victor Sebastián-Pérez

From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors

Alessia Caredda,Angela Corona,Christophe Pannecouque,Elias Maccioni,Enzo Tramontano,Giuseppe Manfroni,Jenny Desantis,Oriana Tabarrini,Serena Massari,Simona Distinto,Stefano Sabatini,Tommaso Felicetti,Violetta Cecchetti

Discovery and antitumor evaluation of novel inhibitors of spermine oxidase

Chunyu Cao,Hongyan Wu,Jianlin Yang,Lidan Sun,Yanlin Wang,You Zhou,Yu Qin

Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysis

Alessia Lucidi,Anastasia De Luca,Anna Maria Caccuri,Antonio Rosato,Blasco Morozzo della Rocca,Chiara Fulci,Dante Rotili,Francesca Sciarretta,Luigi Quintieri,Veronica Di Paolo

Potential multifunctional agents with anti-hepatoma and anti-inflammation properties by inhibiting NF-кB activation

Chang-Ming Su,Cheng Yang,Chun-Hua Wang,Gui-Ge Hou,Hong-Qin Zhang,Mei Liu,Yun Hou

Synthesis, antiasthmatic, and insecticidal/antifungal activities of allosamidins

Gangliang Huang,Hualiang Huang

Identification of novel indole derivatives acting as inhibitors of the Keap1–Nrf2 interaction

Antonia Sacchi,Barbara Cosimelli,Ettore Novellino,Giampietro Viola,Giorgio Amendola,Giovanni Greco,Roberta Bortolozzi,S,Sonia Laneri,ro Cosconati

Synthesis and biological evaluation of novel 8-substituted quinoline-2-carboxamides as carbonic anhydrase inhibitors

Andrea Angeli,Claudiu T. Supuran,Mohammed Arifuddin,Pavitra S. Thacker,Pirpasha Shaikh

Synthesis of a new series of 3-functionalised-1-phenyl-1,2,3-triazole sulfamoylbenzamides as carbonic anhydrase I, II, IV and IX inhibitors

Andrea Angeli,Baijayantimala Swain,Claudiu T. Supuran,Mohammed Arifuddin,Pavitra S. Thacker,Priti Singh,Srinivas Angapelly

Blocking the FKBP12 induced dendrimeric burst in aberrant aggregation of α-synuclein by using the ElteN378 synthetic inhibitor

Gabriella Caminati,Maria Raffaella Martina,Piero Procacci,Stefano Menichetti

Novel tyrosinase inhibitory peptide with free radical scavenging ability

Tingyuan Tan,Yi Zhang,Yujiao Wang,Zhen Guo,Zhiwei Shen

Synthesis and in vitro and in vivo anti-inflammatory activity of novel 4-ferrocenylchroman-2-one derivatives

Ban-Feng Ruan,Bang-Nian Shen,Guang-Ping Tai,Li Gao,Liu-Zeng Chen,Qing-Shan Li,Wei-Yun Guo,Xin-Hua Liu

Extraction and derivatisation of active polysaccharides

Gangliang Huang,Yang Liu

Anti-Helicobacter pylori activity of ethoxzolamide

Alex,Anna Roujeinikova,Claudiu T. Supuran,Despina Kotsanas,Jose Garcia-Bustos,Joyanta K. Modak,Mohammad M. Rahman,Rebecca J. Gorrell,Richard L. Ferrero,Terry Kwok,Tony M. Korman,ra Tikhomirova

Anticancer sulfonamide hybrids that inhibit bladder cancer cells growth and migration as tubulin polymerisation inhibitors

Chunlai Liu,Jia Liu,Liu Yu,Ping Wang,Xiling Zhang,Xue Gong

Synthesis and enzyme-based evaluation of analogues L-tyrosine thiol carboxylic acid inhibitor of metallo-β-lactamase IMP-1

Hadi Adibi,Mahboubeh Kavoosi,Omid Khalili Arjom

Novel 2-phenoxypyrido[3,2-b]pyrazin-3(4H)-one derivatives as potent and selective aldose reductase inhibitors with antioxidant activity

Changjin Zhu,Gang Qi,Hongxing Ma,Xin Hao,Zhongfei Han

Dual and selective inhibitors of pteridine reductase 1 (PTR1) and dihydrofolate reductase-thymidylate synthase (DHFR-TS) from Leishmania chagasi

Acássia Benjamim Leal Pires,André Lacerda Braga Teles,Bárbara Velame Ferreira Teixeira,Camila Carane Bitencourt Brito,Humberto Fonseca de Freitas,Marcelo Santos Castilho,Suellen Gon？alves da Silva,Thamires Quadros Froes

Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamides as carbonic anhydrase isoforms I and II inhibitors

Ahmed Elkamhawy,Claudiu T. Supuran,Eun Joo Roh,Mohamed A. Abdelgawad,Silvia Bua,So Ha Lee,Sora Paik,Wagdy M. Eldehna

Dual-target anti-Alzheimer’s disease agents with both iron ion chelating and monoamine oxidase-B inhibitory activity

Bing Gan,Changjun Zhang,Jianan Guo,Jing Su,Renren Bai,Sihang Yu,Tao Zhou,Xiaoying Jiang,Yuanyuan Xie,Zhisheng Mi

Synthesis, computational studies, tyrosinase inhibitory kinetics and antimelanogenic activity of hydroxy substituted 2-[(4-acetylphenyl)amino]-2-oxoethyl derivatives

Amara Mumtaz,Anser Ali,Hummera Rafique,Katarzyna Kotwica-Mojzych,Khurram Afzal,Mariusz Mojzych,Mubashir Hassan,Muhammad Rafiq,Muhammad Rizwan Yousuf,Muhammad Saleem,Samina Afzal,Yasir Nazir,Zaman Ashraf

Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approach

Anna Di Fiore,Claudiu T. Supuran,Daniela Vullo,Emanuela Truppo,Emma Langella,Giuseppina De Simone,Simona Maria Monti

Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity

Anél Petzer,Claudio Ferrante,Daniela Secci,Donatella Bagetta,Francesco Ortuso,Giulia Rotondi,Gokhan Zengin,Jacobus P. Petzer,Lucia Recinella,Paola Chimenti,Paolo Guglielmi,Sheila Leone,Simone Carradori,Stefano Alcaro

Seeking new approach for therapeutic treatment of cholera disease via inhibition of bacterial carbonic anhydrases: experimental and theoretical studies for sixteen benzenesulfonamide derivatives

Claudiu T. Supuran,Clemente Capasso,Daniela Vullo,Francesca Mancuso,Laura De Luca,Rosaria Gitto,Sonia Del Prete

In vitro anticancer potentiality and molecular modelling study of novel amino acid derivatives based on N1,N3-bis-(1-hydrazinyl-1-oxopropan-2-yl) isophthalamide

Asmaa F. Kassem,Eman S. Nossier,Gaber O. Moustafa,Hemat S. Khalaf,Marwa M. Mounier,Sabry Y. Mahmoud,Suliman A. Al-Yousef

Discovery of aminopyridine-containing spiro derivatives as EGFR mutations inhibitors

Anhu Li,Jingrong Li,Lianbao Ye,Ling Wang,Tao Zhao,Wei Gao,Weiqiang Chen,Wenjun Du

Carbazole scaffolds in cancer therapy: a review from 2012 to 2018

Anthony Pr,Marc Le Borgne,Nicolas Bedel,P？l Rongved,Samar Issa,Sa？d Yous,Zouhair Bouaziz,ina

Design and synthesis of phthalazine-based compounds as potent anticancer agents with potential antiangiogenic activity via VEGFR-2 inhibition

Asmaa M. Aboul-Magd,Deena S. Lasheen,Khaled A. M. Abouzid,Salwa Elmeligie,Sohair M. Khojah,Tamer M. Abdelghany,Tamer M. Ibrahim

10H-1,9-diazaphenothiazine and its 10-derivatives: synthesis, characterisation and biological evaluation as potential anticancer agents

Aleks,Beata Morak-M？odawska,Dariusz Ku？mierz,Kinga Suwińska,Krystian Pluta,Magdalena Jurzak,Ma？gorzata Jeleń,Ma？gorzata Latocha,Zenon Czuba,er Shkurenko

Synthesis, activity evaluation, and pro-apoptotic properties of novel 1,2,4-triazol-3-amine derivatives as potent anti-lung cancer agents

Cheng-hao Jin,Chun-yan Zhong,Mei-yu Liu,Qing-qing Qiu,Xian-yu Sun,Xin Wang,Zhen-wang Li

1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery

Béatrice Brion,Claire Raingeval,Isabelle Krimm,Marc Le Borgne,Olivier Cala,Roderick Eliot Hubbard

Novel phthalimide based analogues: design, synthesis, biological evaluation, and molecular docking studies

Abd El-Galil E. Amr,Eman S. Nossier,Ismail M. M. Othman,Mohamed A. M. Gad-Elkareem,Mohamed El-Naggar

Synthesis and bioevaluation of novel steroidal isatin conjugates derived from epiandrosterone/androsterone

Daye Huang,Kaimei Wang,Liqiao Shi,Manli Liu,Ronghua Zhou,Shaoyong Ke,Wei Fang,Zhigang Zhang,Zhongyi Wan

Kinetic and thermodynamic characterisation of HIV-protease inhibitors against E35D↑G↑S mutant in the South African HIV-1 subtype C protease

Eden Padayachee,Glenn Maguire,Johnson Lin,Kruger Hendrik Gerhardus,Sibusiso Maseko,Siyabonga Maphumulo,Sooraj Baijnath,Thavendran Govender,Tricia Naicker,Yasien Sayed

A fast, miniaturised in-vitro assay developed for quantification of lipase enzyme activity

Ariane Menden,Daniel Paris,Davane Hall,Fiona Crawford,Ghania Ait-Ghezala,Michael Mullan,Stefan Crynen,Venkatarian Mathura

Synthesis and biological evaluation of novel N-(piperazin-1-yl)alkyl-1H-dibenzo[a,c]carbazole derivatives of dehydroabietic acid as potential MEK inhibitors

A-Liang Li,Chao Qiao,Hao Chen,Ting-Ting Miao,Wen Gu,Wen-Yan Wang

Go




©2008-2020 OALib, Inc | Public user content licensed CC-BY 4.0 unless otherwise specified. OALib ISSN Online: 2333-9721 OALib ISSN Print: 2333-9705