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Toxicologic Pathology

ISSN Print: 0192-6233

ISSN Online: 1533-1601

主页: https://journals.sagepub.com/loi/tpxb

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Translational Research: The Cornerstone for Medical Technology Advancement

Armando Tellez,Juan F. Granada,Marco Ferrone

Histology Strategies for Medical Implants and Interventional Device Studies

Armando Tellez,Brian C. Tabb,Joan R. Wicks,Maureen O’Brien,Serge D. Rousselle

Spontaneous Cholangiofibrosis in a Wistar Rat

Ke Chen,Peter C. Mann,Shaung Qiu,Tao Chen

Cytoplasmic Vacuolation and Tapetal Changes Induced by a Novel Analgesic Agent in Beagle Dogs

Dai Watanabe,Kei Takahashi,Keiyu Oshida,Makoto Kohno,Mayu Mutsuga,Mayumi Nakajima,Seiki Yamakawa,Shuji Udagawa,Yasuhiro Morita,Yohei Miyamoto

Toxicity and Safety Study of D

Abraham Nyska,Noam Emanuel,Sefi Rosenfeld,Shlomo Nedvetzki,Yuval Ramot

Thymomas and Associated Hyperplastic Lesions in Wistar Hannover Rats

Junko Sato,Minoru Tsuchitani,Takeshi Kanno,Tetsuro Kurotaki,Yuki Tomonari,Yumi Wako

Reevaluation of Hepatocellular Neoplasms in CD

Amera K. Remick,Erin M. Quist,Gary A. Boorman,James A. Swenberg,Jerry F. Hardisty,John M. Cullen,Les Freshwater,Robert R. Maronpot

Molecular Pathological Differences in Global Gene Expression between Two Sustained Proliferative Lesions, Nodular Regenerative Hepatocellular Hyperplasia and Hepatocellular Adenoma, in Mice

Aki Kijima,Kumiko Ogawa,Shinji Takasu,Takashi Umemura,Yuh Yokoo,Yuji Ishii

Balloons and Stents and Scaffolds: Preclinical Evaluation of Interventional Devices for Occlusive Arterial Disease

Laura E. Leigh Perkins,Marian K. Rippy

What Is “Preclinical Device Pathology”: An Introduction of the Unfamiliar

Nicole Kirchhof

Pathology Approaches to Determine Safety and Efficacy of Cardiac Ablation Catheters

Marian K. Rippy,Serge D. Rousselle,William C. Stoffregen

Histopathological Evaluation of Orthopedic Medical Devices: The State

Derick Vollmer,James Stanley,Madeleine Chagnon,Michel Assad,Nicolette Jackson

Evaluation of Magnesium

Louis-Georges Guy,Madeleine Chagnon,Nicolette Jackson

Pathology of Bioabsorbable Implants in Preclinical Studies

Abraham Nyska,Nicolette D. Jackson,Serge D. Rousselle,Yuval Ramot

Toxicologic Pathology Forum*: Opinion on Integrating Innovative Digital Pathology Tools in the Regulatory Framework

Alain Piton,Béatrice E. Gauthier,Donal O’Shea,Frédéric Gervais,Gregory Hamm,Vanessa L. Schumacher

Time Course of Axon and Myelin Degeneration in Peripheral Nerves in Experimental Autoimmune Neuritis Rats

Chihiro Kaneko,Emi Tomikawa,Kojiro Hara,Mayu Mutsuga,Yohei Miyamoto,Yuko Togashi

Histological Changes of the Testicular Interstitium during Postnatal Development in Microminipigs

Akihisa Kangawa,Masatoshi Shibata,Masayoshi Otake,Satoko Enya,Toshinori Yoshida

Evolving the Role of Discovery

Jan Klapwijk,Peter Clements,Richard Haworth,Rick Adler,Sean Maguire,Sunish Mohanan

Histopathological Findings in Cynomolgus Macaques (Macaca fascicularis) Consistent with Secondary Immunological Reaction to Biotherapeutics with an Emphasis on the CNS and Eye

Alys E. Bradley,Matt Smith,Maurice Cary,Melissa Czajkowski,Stuart W. Naylor,Warren Harvey

Intranodal Angiomyomatous Hamartoma in a Cynomolgus Monkey

André Almeida Schenka,Bernard Palate,Catherine Thirion-Delalande,Frédéric Gervais,Roy Forster

Trends in Liver and Skin Tumor Prevalence in Brown Bullhead (Ameiurus nebulosus) from the Anacostia River, Washington, DC, and Nearby Waters

Alfred E. Pinkney,John C. Harshbarger,Michael A. Rutter,Peter C. Sakaris

Acute Histopathologic Findings Related to Needle Puncture Trauma during Subcutaneous Injection in the Sprague

Abraham Nyska,H. Krishnappa,John E. Dillberger,Kamala Kannan,Sathish Reddy,Yuval Ramot

Ocular Medical Devices: Histologic Technique and Histopathologic Evaluation of the Biocompatibility and Performance

Elodie Drevon-Gaillot

Toxicologic Pathology Forum*: Opinion on Sexual Maturity and Fertility Assessment in Long

C. Marc Luetjens,Gerhard F. Weinbauer,Lars Mecklenburg

Epithelial–mesenchymal Transition Phenotypes in Vertebral Metastases of Lung Cancer

Alexandra M. Dieterly,Arvin H. Soepriatna,Chinyere M. Kemet,Craig J. Goergen,Gozde Uzunalli,L. Tiffany Lyle

Toxicologic Pathology Forum*: Opinion on Considerations for the Use of Whole Slide Images in GLP Pathology Peer Review

Alys Bradley,Matt Jacobsen

An Overview on the Considerations for the Planning of Nonclinical Necropsies for Medical Device Studies

James R. L. Stanley,John H. Keating,Kathryn J. San Souci

Method for Combined Observation of Serial Sections of Stented Arteries Embedded in Resin by Light Microscopy and Transmission Electron Microscopy

Atsushi Isobe,Fumiaki Kumagai,Hisako Terao,Hitomi Hagiwara,Junko Souba,Kasuke Nagano,Kouichi Iwatani,Masako Tasaki,Yoshiaki Saito

Preclinical Evaluation of Mesh Implants: The Pathologist’s Perspective

Fernando Garcia-Polite,John H. Keating,Raffaele Melidone

Scientific and Regulatory Policy Committee Points to Consider*: Review of Scientific and Regulatory Policy Committee Points to Consider: Review of Current Practices for Ultrastructural Pathology Evaluations in Support of Nonclinical Toxicology Studies

Bruce E. LeRoy,Evan B. Janovitz,Heike A. Marxfeld,James T. Meehan,John R. Megill,Natalie D. Keirstead,Regis G. Masson,Richard A. Peterson

Toxicologic Pathology Forum: Current Status on the Use of Animal Models of Human Disease in the Pharmaceutical Industry in Japan in Nonclinical Safety Assessment–Opinion Paper

Kazuto Watanabe,Keiko Motoyama,Kiyoshi Kinoshita,Masayuki Tomohiro,Michio Fujiwara,Mitsunori Maeda,Riichiro Yonezawa,Shoji Sasaki,Takeshi Okabe,Yasushi Kimura,Yuko Mitobe

Functional and Morphological Characteristics of Pancreatic Islet Lesions Induced by Quinolone Antimicrobial Agent Gatifloxacin in Rats

Kazuhiko Mori,Koichi Yabe,Sanae Takada,Takami Suzuki,Yuka Yamamoto

Characterization of 5

Chihiro Noguchi,Fumiko Asanuma,Hiroto Miyata,Kenta Matsue,Minoru Sasaki,Yutaka Nakanishi

Local Toxicity of Topically Administrated Thermoresponsive Systems: In Vitro Studies with In Vivo Correlation

Abraham Nyska,Ayelet Shabtay-Orbach,Boaz Mizrahi,Sivan Yogev

Pathological Safety Assessment in Preclinical Neurothrombectomy Studies

Scott A. Katzman,Taylor A. Spangler

Drug

Andreas Brink,Anne Eichinger-Chapelon,Barbara Lenz,Bj？rn Jacobsen,Christian Freichel,Jean-Christophe Hoflack,Mudher Albassam

Pathological Features of Corneal Phospholipidosis in Juvenile White Rabbits Induced by Ocular Instillation of Chloroquine or Amiodarone

Haruko Koizumi,Hiroshi Satoh,Masaaki Kurata,Shingo Nemoto,Yoshihiro Takei,Yoshinori Yamagiwa

Variability of Spleen and Mesenteric Lymph Node in Control Cynomolgus Monkeys (Macaca fascicularis) from Nonclinical Safety Studies: A Retrospective Assessment

James Reindel,Jonathan Werner,Nancy E. Everds,W. A. Craven

Introduction to Currently Applied Device Pathology

Alan Glowczwski,Anne-Marie Ginn-Hedman,Brad R. Weeks,Breanna F. Brocklesby,Cedric B. Robinson,Courtney N. Kaulfus,Fatima H. Charara,Fred J. Clubb,Molly C. Friedemann,Nicole A. Mehta,Staci L. Jessen,Steven Jokerst

Refinement, Reduction, and Replacement (3R) Strategies in Preclinical Testing of Medical Devices

Samuel H. Gilbert,Victoria A. Hampshire

Different Vascular Responses to a Bare Nitinol Stent in Porcine Femoral and Femoropopliteal Arteries

Armando Tellez,Atsushi Sakaoka,Hitomi Hagiwara,Junko Souba,Kasuke Nagano,Masako Tasaki,Serge D. Rousselle,Takato Matsuda

Regional Draining Lymph Nodes: Considerations for Medical Device Studies

Lyn M. Wancket

Neurologic Medical Device Overview for Pathologists

Jaime Paulin,Juliana S. Lee,Mark T. Butt,Sarah D. Cramer,William C. Stoffregen

Compilation of International Standards and Regulatory Guidance Documents for Evaluation of Biomaterials, Medical Devices, and 3

JoAnn C. L. Schuh,Kathleen A. Funk

Biodegradability and Safety Study of LifeMesh？, a Novel Self

Abraham Nyska,Amir Hadid,Guy Klaiman,Michal Steiner,Michal Sudak,Noam Kronfeld,Yuval Ramot

Interstitial Adipocytes in the Beagle Dog and New Zealand White Rabbit Choroid Plexus

Curtis Colleton,Daniel Rudmann

A Transient Developmental Background Finding in the Retina Observed in Neonatal Dogs in Juvenile Toxicology Studies

Amera K. Remick,Brian C. Gilger,Janet M. Petruska,Keith Robinson,Mark Vezina,Martin Bussières,Richard R. Dubielzig,Typhaine Lejeune

The Endothelin

Alexander T. Pearson,Gregory T. Clines,Jack R. Harkema,Katrina L. Clines,Marian A. Esvelt,Mark J. Hoenerhoff,Melissa C. Dyson,Zachary T. Freeman

The Emergence of Microphysiological Systems (Organs

Daniel G. Rudmann

Comparison of the Class Effects of Antisense Oligonucleotides in CByB6F1

Chris N. Papagiannis,Christine M. Hoffmaster,Jeffery A. Engelhardt,Jill A. Hsiao,John E. Matson,Laura S. Zwick,Noah M. Post,Scott P. Henry,Sebastien A. Burel,Tae-Won Kim

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