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ISSN: 2333-9721
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A putative silencer variant in a spontaneous canine model of retinitis pigmentosa

Abdul Kadir Mukarram,Carsten O. Daub,Hannes Lohi,Ileana B. Quintero,Juha Kere,Kaisa Ky？stil？,Kaisa Wickstr？m,Maria Kaukonen,Marjo K. Hyt？nen,Meharji Arumilli,Saila Holopainen,Sari Jalom？ki,the DoGA Consortium

Global mistranslation increases cell survival under stress in Escherichia coli

Deepa Agashe,Laasya Samhita,Parth K. Raval

Correction: Regulation of ATG4B Stability by RNF5 Limits Basal Levels of Autophagy and Influences Susceptibility to Bacterial Infection

Carlos López-Otín,Cheryl Y. M. Okumura,Ersheng Kuang,Huei-Jiun Yang,Ingrid R. Niesman,Jianfei Qi,John C. Reed,Limor Broday,Sharon Sheffy-Levin,Tal Varsano,Victor Nizet,Vincent Chih-Wen Shu,Wei Yuan Yang,Ze'ev A. Ronai

Correction: The persimmon genome reveals clues to the evolution of a lineage-specific sex determination system in plants

Hideki Hirakawa,Hideki Nagasaki,Isabelle M. Henry,Kenta Shirasawa,Luca Comai,Ryutaro Tao,Takashi Akagi

The temporal regulation of TEK contributes to pollen wall exine patterning

Jian-Qiao Hou,Jun Zhu,Ling-Li Hou,Min Yang,Qiu-Ye Zeng,Shuang-Xi Xiong,Yue Lou,Zhong-Nan Yang

Dynamic genetic architecture of yeast response to environmental perturbation shed light on origin of cryptic genetic variation

Yanjun Zan,？rjan Carlborg

Depletion of Ric-8B leads to reduced mTORC2 activity

Alice H. Reis,Bettina Malnic,Cleiton F. Machado,Elisa R. Donnard,Jose G. Abreu,Luciana M. Gutiyama,Maíra H. Nagai,Pedro A. F. Galante,Victor P. S. Xavier,William T. Festuccia

An EHBP-1-SID-3-DYN-1 axis promotes membranous tubule fission during endocytic recycling

Anbing Shi,Hongjie Zhang,Jinghu Gao,Juan Chen,Linyue Zhao,Long Lin,Peixiang Wang,Qian Luo,Shuyao Liu,Xin Fu,Ziyang Lin

RNA Polymerase II CTD phosphatase Rtr1 fine-tunes transcription termination

Amber L. Mosley,Asha K. Boyd,Gerald O. Hunter,Jose F. Victorino,Katlyn H. Burriss,Megan A. Zimmerly,Melanie J. Fox,Rachel R. Chan,Sarah A. Peck Justice,Whitney R. Smith-Kinnaman,Yunlong Liu

Cell cycle transcriptomics of Capsaspora provides insights into the evolution of cyclin-CDK machinery

Alberto Pérez-Posada,Andrej Ondracka,Eduard Oca？a-Pallarès,I？aki Ruiz-Trillo,Omaya Dudin

The alarmones (p)ppGpp are part of the heat shock response of Bacillus subtilis

Aaron M. Nuss,Bertrand Beckert,Christian K. Frese,Daniel N. Wilson,Gert Bange,Heinrich Sch？fer,Ingo Hantke,Kristina Driller,Kür？ad Turgay,Libor Krásny,Michael Beckstette,Petra Dersch,Petra Sudzinová,Volkhard Kaever,Wieland Steinchen

Reciprocal c-di-GMP signaling: Incomplete flagellum biogenesis triggers c-di-GMP signaling pathways that promote biofilm formation

Calvin K. Lee,Christopher B. Rose,Daniel C. Wu,David Zamorano-Sánchez,Eric M. Bilotta,Fernando A. Pagliai,Fitnat H. Yildiz,Gerard C. L. Wong,Giordan Kitts,Jin Hwan Park,Kyle A. Floyd

A kinesin Klp10A mediates cell cycle-dependent shuttling of Piwi between nucleus and nuage

Charlotte P. Choi,Cuie Chen,John K. Kim,Steven E. Jacobsen,Suhua Feng,Yukiko M. Yamashita,Zsolt G. Venkei

Drosophila insulin-like peptide 2 mediates dietary regulation of sleep intensity

Alex C. Keene,Benjamin Kottler,Elizabeth B. Brown,Kreesha D. Shah,Richard Faville

Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin

Brian J. Beliveau,C.-ting Wu,David Acevedo,Gary H. Karpen,Giacomo Cavalli,Nuno M. C. Martins,Yuh Chwen G. Lee,Yuki Ogiyama

Evidence of defined temporal expression patterns that lead a gram-negative cell out of dormancy

Carl E. Bauer,Nandhini Ashok

Light affects tissue patterning of the hypocotyl in the shade-avoidance response

Anko Blaakmeer,Bin Sun,Daniel Straub,Delphine Ménard,Edouard Pesquet,Esther Botterweg-Paredes,Lorenzo Mineri,Shin-Young Hong,Stephan Wenkel,Valdeko Kruusvee,Yakun Xie

WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motility

Kenneth G. Campellone,Margaret D. Zimmer,Shail Kabrawala

GLP-1 Notch—LAG-1 CSL control of the germline stem cell fate is mediated by transcriptional targets lst-1 and sygl-1

Ariz Mohammad,Beth Bowman,Eric Tycksen,Huiyan Huang,Jian Chen,Nanette Pazdernik,Tim Schedl

The Caenorhabditis elegans homolog of the Evi1 proto-oncogene, egl-43, coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasion

Alex Appert,Alex Hajnal,Evelyn Lattmann,Julie Ahringer,Michael Daube,Przemyslaw Stempor,Ting Deng

Autophagy compensates for defects in mitochondrial dynamics

Barbara Conradt,Christian Fischer,Fabian K？hler,Laetitia Chauve,Madeleine F. Premm,Michael Witting,Olivia Casanueva,Simon Haeussler,Stéphane G. Rolland

Girdin is a component of the lateral polarity protein network restricting cell dissemination

Alexandra Jetté,Clémence L. Gamblin,Cornélia Biehler,Elise Houssin,Li-Ting Wang,Luke McCaffrey,Myriam Sévigny,Patrick Laprise,Rachel Catterall

A Snf1-related nutrient-responsive kinase antagonizes endocytosis in yeast

Jason A. MacGurn,Jessica M. Tumolo,Nathaniel L. Hepowit,Samika S. Joshi

What is ancestry?

Aylwyn Scally,Iain Mathieson

Correction: Mck1 kinase is a new player in the DNA damage checkpoint pathway

The PLOS Genetics Staff

XPF–ERCC1: Linchpin of DNA crosslink repair

Peter J. McHugh

Conserved nuclear hormone receptors controlling a novel plastic trait target fast-evolving genes expressed in a single cell

Bogdan Sieriebriennikov,Christian R？delsperger,Eduardo Moreno,Hanh Witte,James W. Lightfoot,Ralf J. Sommer,Shuai Sun

Is adaptation limited by mutation? A timescale-dependent effect of genetic diversity on the adaptive substitution rate in animals

Benoit Nabholz,Emeric Figuet,Marie-Ka Tilak,Marjolaine Rousselle,Nicolas Galtier,Paul Simion

Postglacial migration shaped the genomic diversity and global distribution of the wild ancestor of lager-brewing hybrids

Chris Todd Hittinger,Christian A. Lopes,Dana A. Opulente,David Peris,Diego Libkind,Juan I. Eizaguirre,Kayla Sylvester,Kelly V. Buh,Martin Jarzyna,María E. Rodríguez,Quinn K. Langdon

The plant mobile domain proteins MAIN and MAIL1 interact with the phosphatase PP7L to regulate gene expression and silence transposable elements in Arabidopsis thaliana

Etienne Bucher,Guillaume Moissiard,James Wohlschlegel,Jean-Marc Deragon,Julie Descombin,Melody Nicolau,Nathalie Picault,Steven E. Jacobsen,Suhua Feng,Yasaman Jami-Alahmadi

FANCJ helicase promotes DNA end resection by facilitating CtIP recruitment to DNA double-strand breaks

Ganesh Nagaraju,Sarmi Nath

Waking up quiescent neural stem cells: Molecular mechanisms and implications in neurodevelopmental disorders

Hongyan Wang,Jiawen Huang,Wei Yung Ding

Technical and social issues influencing the adoption of preprints in the life sciences

Jessica K. Polka,Naomi C. Penfold

The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification

Alun R. Barnard,Fiona Young,Ian J. Jackson,Jimi Wills,Lisa Mckie,Robert E. MacLaren,Sally H. Cross,Sam Riley,Toby W. Hurd

The MAPK substrate MASS proteins regulate stomatal development in Arabidopsis

Chao Bian,Juan Dong,Rong Di,Xiaoyu Guo,Xueyi Xue

Is imprinting the result of “friendly fire” by the host defense system?

Colum P. Walsh,Miroslava Ondi？ová,Rebecca J. Oakey

Loss of Cdc13 causes genome instability by a deficiency in replication-dependent telomere capping

Dominic Palazzola,Erin Bonnell,Rachel E. Langston,Raymund J. Wellinger,Ted Weinert

The Drosophila FUS ortholog cabeza promotes adult founder myoblast selection by Xrp1-dependent regulation of FGF signaling

Céline Sijlmans,Divita Kulshrestha,Erik Storkebaum,Frank Schnorrer,Ioannis Alexopoulos,Manuela Weitkunat,Marica Catinozzi,Marie Frickenhaus,Marije Been,Moushami Mallik

Parallelism in eco-morphology and gene expression despite variable evolutionary and genomic backgrounds in a Holarctic fish

Andrey Yurchenko,Arne Jacobs,Ben F. Koop,Colin E. Adams,David R. Minkley,Eric B. Rondeau,Jong S. Leong,Kathryn R. Elmer,Madeleine Carruthers,Natalia V. Gordeeva,Oliver Hooker,Sergey S. Alekseyev

Mutations on ent-kaurene oxidase 1 encoding gene attenuate its enzyme activity of catalyzing the reaction from ent-kaurene to ent-kaurenoic acid and lead to delayed germination in rice

Dongli He,Hui Zhang,Kun Wang,Ming Li,Pingfang Yang

Loss of androgen signaling in mesenchymal sonic hedgehog responsive cells diminishes prostate development, growth, and regeneration

Adam Olson,Dong-Hoon Lee,Erika Hooker,Eun-Jeong Yu,Gerald R. Cunha,Jiaqi Mi,Joseph Aldahl,Joseph Geradts,Monica Wong,Ruoyu Sheng,Vien Le,Won Kyung Kim,Yongfeng He,Zijie Sun

Getting clear about the F-word in genomics

Alexander F. Palazzo,Stefan Linquist,W. Ford Doolittle

Interaction between host genes and Mycobacterium tuberculosis lineage can affect tuberculosis severity: Evidence for coevolution?

Catherine M. Stein,Christian Wejse,Eddie M. Wampande,Giorgio Sirugo,Harriet Mayanja-Kizza,Jacquelaine Bartlett,Kyle Fluegge,Michael L. McHenry,Moses Joloba,Noemi B. Hall,Penelope Benchek,Robert P. Igo Jr,Sarah A. Tishkoff,Scott M. Williams,Sebastien Gagneux,W. Henry Boom

Sex biased expression and co-expression networks in development, using the hymenopteran Nasonia vitripennis

Alfredo Rago,John H. Werren,John K. Colbourne

ELF5 modulates the estrogen receptor cistrome in breast cancer

Alexander Swarbrick,Andrew M. K. Law,Catherine L. Piggin,Christoph Krisp,Christopher J. Ormandy,Daniel L. Roden,David Gallego-Ortega,Jason S. Carroll,Maria Kalyuga,Mark P. Molloy,Matthew J. Naylor,Nenad Bartonicek,Samantha R. Oakes,Susan J. Clark,Warren Kaplan

DNA methylation-mediated repression of exosomal miR-652-5p expression promotes oesophageal squamous cell carcinoma aggressiveness by targeting PARG and VEGF pathways

Dan Wang,Guogui Sun,Huan Wang,Jie Zhang,Jilong Yang,Meiyue Liu,Peng Gao,Siyuan Chen,Wei Wang,Yi Niu,Zhao Yang

The coordinate actions of calcineurin and Hog1 mediate the stress response through multiple nodes of the cell cycle network

Cassandra M. Leech,Haibo Liu,Heather E. Arsenault,Jennifer A. Benanti,Jianhong Ou,Lihua Julie Zhu,Mackenzie J. Flynn

ArdC, a ssDNA-binding protein with a metalloprotease domain, overpasses the recipient hsdRMS restriction system broadening conjugation host range

Fernando de la Cruz,Gabriel Moncalián,Irene del Campo,Lorena González-Montes,M. Pilar Garcillán-Barcia

Environmentally-relevant exposure to diethylhexyl phthalate (DEHP) alters regulation of double-strand break formation and crossover designation leading to germline dysfunction in Caenorhabditis elegans

Kurunthachalam Kannan,Laura I. Lascarez-Lagunas,Luciann Cuenca,Marina Martinez-Garcia,Mónica P. Colaiácovo,Nara Shin,Rajendiran Karthikraj,Saravanapriah Nadarajan

Single-nucleus RNA-seq identifies divergent populations of FSHD2 myotube nuclei

Ali Mortazavi,Katherine Williams,Kyoko Yokomori,Nam Viet Nguyen,Rabi Tawil,Shan Jiang,Weihua Zeng,Xiangduo Kong,Xinyi Ma

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