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OALib Journal期刊
ISSN: 2333-9721
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ISSN Print: 1946-6242
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Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2
Targeting p53-dependent stem cell loss for intestinal chemoprotection
Methicillin-resistant Staphylococcus aureus causes sustained collecting lymphatic vessel dysfunction
Pharmacokinetics of rifapentine and rifampin in a rabbit model of tuberculosis and correlation with clinical trial data
Ablation of the stress protease OMA1 protects against heart failure in mice
In situ formed reactive oxygen species–responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy
The root problem of heart valve engineering
The broad socioeconomic benefits of vaccination
Mechanobiologically optimized 3D titanium-mesh scaffolds enhance bone regeneration in critical segmental defects in sheep
Eradication of spontaneous malignancy by local immunotherapy
Genetically modified lentiviruses that preserve microvascular function protect against late radiation damage in normal tissues
Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade
Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia
Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma
Rapid detection of Mycobacterium tuberculosis in sputum with a solvatochromic trehalose probe
Oncogenic JAK2 V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms
A digital microfluidic system for serological immunoassays in remote settings
Microbial ecology perturbation in human IgA deficiency
T cell–induced CSF1 promotes melanoma resistance to PD1 blockade
Vaccine waning and mumps re-emergence in the United States
Illusory movement perception improves motor control for prosthetic hands
FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis
Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers
Smartphone-based blood pressure monitoring via the oscillometric finger-pressing method
Fast direct neuronal signaling via the IL-4 receptor as therapeutic target in neuroinflammation
Medication development in opioid addiction: Meaningful clinical end points
PPARγ agonist pioglitazone reverses pulmonary hypertension and prevents right heart failure via fatty acid oxidation
High-throughput sequencing of the T cell receptor β gene identifies aggressive early-stage mycosis fungoides
Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer
Postnatal Zika virus infection is associated with persistent abnormalities in brain structure, function, and behavior in infant macaques
A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix
Diagnosis of genetic diseases in seriously ill children by rapid whole-genome sequencing and automated phenotyping and interpretation
GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells
A cytochrome P450 allele confers pyrethroid resistance on a major African malaria vector, reducing insecticide-treated bednet efficacy
Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment in rodent spinal cord injury models
Impact of antibiotic treatment and host innate immune pressure on enterococcal adaptation in the human bloodstream
Chronic hypoxia–induced Cirbp hypermethylation attenuates hypothermic cardioprotection via down-regulation of ubiquinone biosynthesis
Maternal immunization confers protection against neonatal herpes simplex mortality and behavioral morbidity
Autologous tumor cell–derived microparticle-based targeted chemotherapy in lung cancer patients with malignant pleural effusion
Challenges for mesenchymal stromal cell therapies
Opioid overdose detection using smartphones
Loss of HDAC3 results in nonreceptive endometrium and female infertility
Estimating cholera incidence with cross-sectional serology
In utero and postnatal VX-770 administration rescues multiorgan disease in a ferret model of cystic fibrosis
The nonlesional skin surface distinguishes atopic dermatitis with food allergy as a unique endotype
Brain metabolism modulates neuronal excitability in a mouse model of pyruvate dehydrogenase deficiency
DP2 antagonism reduces airway smooth muscle mass in asthma by decreasing eosinophilia and myofibroblast recruitment
Biology, biography, and the translational gap
Clinical-grade stem cell–derived retinal pigment epithelium patch rescues retinal degeneration in rodents and pigs
Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant TFH cells
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