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OALib Journal期刊
ISSN: 2333-9721
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ISSN Print: 2157-9024

ISSN Online:

主页: https://www.nature.com/oncsis

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Histone demethylase KDM6B has an anti-tumorigenic function in neuroblastoma by promoting differentiation

The CSN3 subunit of the COP9 signalosome interacts with the HD region of Sos1 regulating stability of this GEF protein

TREM2 acts as a tumor suppressor in hepatocellular carcinoma by targeting the PI3K/Akt/β-catenin pathway

Cullin 5 is a novel candidate tumor suppressor in renal cell carcinoma involved in the maintenance of genome stability

Activation of c-Met in cancer cells mediates growth-promoting signals against oxidative stress through Nrf2-HO-1

Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB

Study of Cathepsin B inhibition in VEGFR TKI treated human renal cell carcinoma xenografts

Glutamine synthetase is necessary for sarcoma adaptation to glutamine deprivation and tumor growth

Endogenous arginase 2 as a potential biomarker for PEGylated arginase 1 treatment in xenograft models of squamous cell lung carcinoma

Alleles of Insm1 determine whether RIP1-Tag2 mice produce insulinomas or nonfunctioning pancreatic neuroendocrine tumors

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance

A negative feedback loop between XBP1 and Fbw7 regulates cancer development

Transactivation of human endogenous retroviruses by tumor viruses and their functions in virus-associated malignancies

Regulation of estrogen signaling and breast cancer proliferation by an ubiquitin ligase TRIM56

LXRα limits TGFβ-dependent hepatocellular carcinoma associated fibroblast differentiation

Transcriptional and functional consequences of TP53 splice mutations in colorectal cancer

Ibrutinib induces chromatin reorganisation of chronic lymphocytic leukaemia cells

Estrogen receptor-α regulation of microRNA-590 targets FAM171A1—a modifier of breast cancer invasiveness

Blocking CXCLs–CXCR2 axis in tumor–stromal interactions contributes to survival in a mouse model of pancreatic ductal adenocarcinoma through reduced cell invasion/migration and a shift of immune-inflammatory microenvironment

Human colon cancer cells highly express myoferlin to maintain a fit mitochondrial network and escape p53-driven apoptosis

PEST-containing nuclear protein regulates cell proliferation, migration, and invasion in lung adenocarcinoma

Increased expression of NAF1 contributes to malignant phenotypes of glioma cells through promoting protein synthesis and associates with poor patient survival

CUL4B promotes prostate cancer progression by forming positive feedback loop with SOX4

ESCRT-III is necessary for the integrity of the nuclear envelope in micronuclei but is aberrant at ruptured micronuclear envelopes generating damage

Hypomethylation at non-CpG/CpG sites in the promoter of HIF-1α gene combined with enhanced H3K9Ac modification contribute to maintain higher HIF-1α expression in breast cancer

Inhibition of HGF/MET signaling decreases overall tumor burden and blocks malignant conversion in Tpl2-related skin cancer

Dihydroartemisinin inhibits prostate cancer via JARID2/miR-7/miR-34a-dependent downregulation of Axl

Most canine ameloblastomas harbor HRAS mutations, providing a novel large-animal model of RAS-driven cancer

Cell division cycle associated 5 promotes colorectal cancer progression by activating the ERK signaling pathway

Tumor-derived exosomal HMGB1 promotes esophageal squamous cell carcinoma progression through inducing PD1+ TAM expansion

Natural killer cells limit the clearance of senescent lung adenocarcinoma cells

TBX3 represses TBX2 under the control of the PRC2 complex in skeletal muscle and rhabdomyosarcoma

ZFHX3 is indispensable for ERβ to inhibit cell proliferation via MYC downregulation in prostate cancer cells

Phosphorylation of 14-3-3ζ links YAP transcriptional activation to hypoxic glycolysis for tumorigenesis

A functional CRISPR/Cas9 screen identifies kinases that modulate FGFR inhibitor response in gastric cancer

Deep sequencing and pathway-focused analysis revealed multigene oncodriver signatures predicting survival outcomes in advanced colorectal cancer

p38 MAPK pathway and its interaction with TRF2 in cisplatin induced chemotherapeutic response in head and neck cancer

Platelet-derived growth factor receptor-α and -β promote cancer stem cell phenotypes in sarcomas

Chromosomal instability-induced senescence potentiates cell non-autonomous tumourigenic effects

LGR5 regulates gastric adenocarcinoma cell proliferation and invasion via activating Wnt signaling pathway

TTK promotes mesenchymal signaling via multiple mechanisms in triple negative breast cancer

ΔNp63 regulates the expression of hyaluronic acid-related genes in breast cancer cells

FIBP knockdown attenuates growth and enhances chemotherapy in colorectal cancer via regulating GSK3β-related pathways

The FAK inhibitor BI 853520 exerts anti-tumor effects in breast cancer

Muscarinic acetylcholine receptor 3 mediates vagus nerve-induced gastric cancer

Pannexin 1 inhibits rhabdomyosarcoma progression through a mechanism independent of its canonical channel function

miR-330-5p targets SPRY2 to promote hepatocellular carcinoma progression via MAPK/ERK signaling

CBX2 identified as driver of anoikis escape and dissemination in high grade serous ovarian cancer

Depletion of ZBTB38 potentiates the effects of DNA demethylating agents in cancer cells via CDKN1C mRNA up-regulation

Promotion of tumor progression and cancer stemness by MUC15 in thyroid cancer via the GPCR/ERK and integrin-FAK signaling pathways

©2008-2020 OALib, Inc | Public user content licensed CC-BY 4.0 unless otherwise specified. OALib ISSN Online: 2333-9721 OALib ISSN Print: 2333-9705