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OALib Journal期刊
ISSN: 2333-9721
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ISSN Print: 1476-5551

ISSN Online:

主页: https://www.nature.com/leu

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CXCR5+CD8+ T cells are a distinct functional subset with an antitumor activity

Metformin inhibits IL-6 signaling by decreasing IL-6R expression on multiple myeloma cells

Monitoring tumour burden and therapeutic response through analysis of circulating tumour DNA and extracellular RNA in multiple myeloma patients

SETD2 mutations confer chemoresistance in acute myeloid leukemia partly through altered cell cycle checkpoints

Prognostic and predictive value of a microRNA signature in adults with T-cell lymphoblastic lymphoma

Convenience, satisfaction, health-related quality of life of once-weekly 70 mg/m2 vs. twice-weekly 27 mg/m2 carfilzomib (randomized A.R.R.O.W. study)

Allogeneic hematopoietic cell transplantation compared to chemotherapy consolidation in older acute myeloid leukemia (AML) patients 60–75 years in first complete remission (CR1): an alliance (A151509), SWOG, ECOG-ACRIN, and CIBMTR study

Molecular heterogeneity in peripheral T-cell lymphoma, not otherwise specified revealed by comprehensive genetic profiling

The mutational burden of therapy-related myeloid neoplasms is similar to primary myelodysplastic syndrome but has a distinctive distribution

Sphingosine-1-phosphate signalling drives an angiogenic transcriptional programme in diffuse large B cell lymphoma

The first-in-human study of the pan-PIM kinase inhibitor PIM447 in patients with relapsed and/or refractory multiple myeloma

CD22 CAR T-cell therapy in refractory or relapsed B acute lymphoblastic leukemia

Development and preclinical validation of a novel covalent ubiquitin receptor Rpn13 degrader in multiple myeloma

The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies

Identification of a leukemia-initiating stem cell in human mast cell leukemia

Ikaros tumor suppressor function includes induction of active enhancers and super-enhancers along with pioneering activity

Enasidenib, an inhibitor of mutant IDH2 proteins, induces durable remissions in older patients with newly diagnosed acute myeloid leukemia

Transforming growth factor (TGF)-β pathway as a therapeutic target in lower risk myelodysplastic syndromes

CSF1R and BTK inhibitions as novel strategies to disrupt the dialog between mantle cell lymphoma and macrophages

Inhibitory effects of midostaurin and avapritinib on myeloid progenitors derived from patients with KIT D816V positive advanced systemic mastocytosis

Short telomeres are associated with inferior outcome, genomic complexity, and clonal evolution in chronic lymphocytic leukemia

Quality of life and mood of older patients with acute myeloid leukemia (AML) receiving intensive and non-intensive chemotherapy

Inhibition of SYK or BTK augments venetoclax sensitivity in SHP1-negative/BCL-2-positive diffuse large B-cell lymphoma

Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice

Expression and functional relevance of long non-coding RNAs in acute myeloid leukemia stem cells

Selective targeting of multiple myeloma by B cell maturation antigen (BCMA)-specific central memory CD8+ cytotoxic T lymphocytes: immunotherapeutic application in vaccination and adoptive immunotherapy

Kdm6b regulates context-dependent hematopoietic stem cell self-renewal and leukemogenesis

Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma

Biology and prognostic impact of clonal plasmacytoid dendritic cells in chronic myelomonocytic leukemia

CD8+ T cells expand stem and progenitor cells in favorable but not adverse risk acute myeloid leukemia

Blocking ATM-dependent NF-κB pathway overcomes niche protection and improves chemotherapy response in acute lymphoblastic leukemia

A distinct epigenetic program underlies the 1;7 translocation in myelodysplastic syndromes

De novo gene mutations in normal human memory B cells

Mitochondrial apoptosis is induced by Alkoxy phenyl-1-propanone derivatives through PP2A-mediated dephosphorylation of Bad and Foxo3A in CLL

Targeted killing of TNFR2-expressing tumor cells and Tregs by TNFR2 antagonistic antibodies in advanced Sézary syndrome

Cancer from the perspective of stem cells and misappropriated tissue regeneration mechanisms

Activation of NF-κB driven inflammatory programs in mesenchymal elements attenuates hematopoiesis in low-risk myelodysplastic syndromes

CAR T-cells for T-cell malignancies: challenges in distinguishing between therapeutic, normal, and neoplastic T-cells

Bone marrow MSCs in MDS: contribution towards dysfunctional hematopoiesis and potential targets for disease response to hypomethylating therapy

Late treatment-related mortality versus competing causes of death after allogeneic transplantation for myelodysplastic syndromes and secondary acute myeloid leukemia

Responses in multiple myeloma should be assigned according to serum, not urine, free light chain measurements

B7-H3 promotes multiple myeloma cell survival and proliferation by ROS-dependent activation of Src/STAT3 and c-Cbl-mediated degradation of SOCS3

Health-related quality of life, symptom burden, and comorbidity in long-term survivors of acute promyelocytic leukemia

CLL2-BIG: sequential treatment with bendamustine, ibrutinib and obinutuzumab (GA101) in chronic lymphocytic leukemia

The importance of B cell receptor isotypes and stereotypes in chronic lymphocytic leukemia

Randomized comparison of low dose cytarabine with or without glasdegib in patients with newly diagnosed acute myeloid leukemia or high-risk myelodysplastic syndrome

Minimal residual disease quantification by flow cytometry provides reliable risk stratification in T-cell acute lymphoblastic leukemia

Global long terminal repeat activation participates in establishing the unique gene expression programme of classical Hodgkin lymphoma

CD34+CD38？ leukemic stem cell frequency to predict outcome in acute myeloid leukemia

Blood and skin-derived Sezary cells: differences in proliferation-index, activation of PI3K/AKT/mTORC1 pathway and its prognostic relevance

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