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OALib Journal期刊
ISSN: 2333-9721
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ISSN Print: 1546-1718

ISSN Online:

主页: https://www.nature.com/ng

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Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations

Genome-scale screens identify JNK–JUN signaling as a barrier for pluripotency exit and endoderm differentiation

The tomato pan-genome uncovers new genes and a rare allele regulating fruit flavor

Tracing the ancestry of modern bread wheats

Multi-tissue transcriptome analyses identify genetic mechanisms underlying neuropsychiatric traits

A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Evolution of buffering in a genetic circuit controlling plant stem cell proliferation

Detecting the mutational signature of homologous recombination deficiency in clinical samples

The genome of cultivated peanut provides insight into legume karyotypes, polyploid evolution and crop domestication

Genome-wide association study identifies 30 loci associated with bipolar disorder

Durum wheat genome highlights past domestication signatures and future improvement targets

Opportunities and challenges for transcriptome-wide association studies

Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

Interrogation of human hematopoiesis at single-cell and single-variant resolution

Linked-read analysis identifies mutations in single-cell DNA-sequencing data

Gossypium barbadense and Gossypium hirsutum genomes provide insights into the origin and evolution of allotetraploid cotton

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

Long-range interactions between topologically associating domains shape the four-dimensional genome during differentiation

SETD2 regulates the maternal epigenome, genomic imprinting and embryonic development

Resequencing of 429 chickpea accessions from 45 countries provides insights into genome diversity, domestication and agronomic traits

Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids

A genome-wide algal mutant library and functional screen identifies genes required for eukaryotic photosynthesis

Biallelic expansion of an intronic repeat in RFC1 is a common cause of late-onset ataxia

Clinical use of current polygenic risk scores may exacerbate health disparities

Measuring intolerance to mutation in human genetics

Genomic prediction of maize yield across European environmental conditions

Exome sequencing highlights the role of wild-relative introgression in shaping the adaptive landscape of the wheat genome

The genome sequence of segmental allotetraploid peanut Arachis hypogaea

A reinforcing HNF4–SMAD4 feed-forward module stabilizes enterocyte identity

Genomic subtyping and therapeutic targeting of acute erythroleukemia

Probabilistic fine-mapping of transcriptome-wide association studies

Transposable elements drive widespread expression of oncogenes in human cancers

The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity–independent genomic targeting

A linear mixed-model approach to study multivariate gene–environment interactions

ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm

A primer on deep learning in genomics

Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions

High-resolution genetic mapping of putative causal interactions between regions of open chromatin

Comparative genomics of the major parasitic worms

Genebank genomics highlights the diversity of a global barley collection

Cilia-driven cerebrospinal fluid flow directs expression of urotensin neuropeptides to straighten the vertebrate body axis

Subtype-specific regulatory network rewiring in acute myeloid leukemia

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens

An evolutionary framework for measuring epigenomic information and estimating cell-type-specific fitness consequences

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

Neurodevelopmental disease genes implicated by de novo mutation and copy number variation morbidity

Flexible statistical methods for estimating and testing effects in genomic studies with multiple conditions

Error-prone bypass of DNA lesions during lagging-strand replication is a common source of germline and cancer mutations

A map of constrained coding regions in the human genome

©2008-2020 OALib, Inc | Public user content licensed CC-BY 4.0 unless otherwise specified. OALib ISSN Online: 2333-9721 OALib ISSN Print: 2333-9705