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Science China Life Sciences

ISSN Print: 1869-1889

ISSN Online: 1869-1889

主页: http://link.springer.com/journal/11427

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Dawn of ocular gene therapy: implications for molecular diagnosis in retinal disease

Jacques Zaneveld,Feng Wang,Xia Wang,Rui Chen

Studies on abacavir-induced hypersensitivity reaction: a successful example of translation of pharmacogenetics to personalized medicine

YongLi Guo,LeMing Shi,HuiXiao Hong,ZhenQiang Su,James Fuscoe,BaiTang Ning

Control mechanism for the upper airway collapse in patients with obstructive sleep apnea syndrome: a finite element study

RenHan Huang,XiPing Li,QiGuo Rong

Highly efficient uptake of ultrafine mesoporous silica nanoparticles with excellent biocompatibility by Liriodendron hybrid suspension cells

Bing Xia,Chen Dong,WenYi Zhang,Ye Lu,JinHui Chen,JiSen Shi

Four new species of the genus Hymenoscyphus (fungi) based on morphology and molecular data

HuanDi Zheng,WenYing Zhuang

Complete chloroplast genome sequence of Magnolia grandiflora and comparative analysis with related species

XiWen Li,HuanHuan Gao,YiTao Wang,JingYuan Song,Robert Henry,HeZhen Wu,ZhiGang Hu,Hui Yao,HongMei Luo,Kun Luo,HongLin Pan,ShiLin Chen

Transcriptome profiling of the developing postnatal mouse testis using next-generation sequencing

Wei Gong,LinLin Pan,Qiang Lin,YuanYuan Zhou,ChengQi Xin,XiaoMin Yu,Peng Cui,SongNian Hu,Jun Yu

In vivo skin penetration and metabolic path of quantum dots

Lei Tang,ChunLing Zhang,GuangMing Song,Xun Jin,ZhongWei Xu

Inducible regulation of GDNF expression in human neural stem cells

ShuYan Wang,Ping Ren,YunQian Guan,ChunLin Zou,LinLin Fu,Yu Zhang

Comparative study of de novo assembly and genome-guided assembly strategies for transcriptome reconstruction based on RNA-Seq

BingXin Lu,ZhenBing Zeng,TieLiu Shi

‘One Health’ for the people of Hong Kong and the world

Kin-Hang Kok,Hei-Man Vincent Tang,Dong-Yan Jin

Translational oncology toward benefiting cancer patients: the Sun Yat-sen University Cancer Center experience

Mathilde Guerin,ChaoNan Qian,Qian Zhong,Qian Cui,YunMiao Guo,JinXin Bei,JianYong Shao,XiaoFeng Zhu,WenLin Huang,JiangXue Wu,RanYi Liu,Qiang Liu,Jing Wang,WeiHua Jia,XiaoHui Zheng,YiXin Zeng

Risk factors of recurrence in small-sized, node negative breast cancer in young women: a retrospective study in Chinese population

XiaoSan Zhang,PengFei Li,WenJie Ma,WenYu Di,Shu Zhao,QingZu Gao,YuYing Zhao,MaoPeng Yang,QingYuan Zhang

Assessment of the immune responses to Treponema pallidum Gpd DNA vaccine adjuvanted with IL-2 and chitosan nanoparticles before and after Treponema pallidum challenge in rabbits

FeiJun Zhao,XiaoHong Zhang,ShuangQuan Liu,TieBing Zeng,Jian Yu,WeiMing Gu,YueJun Zhang,Xi Chen,YiMou Wu

Testing three pipelines for 18S rDNA-based metabarcoding of soil faunal diversity

ChenXue Yang,YingQiu Ji,XiaoYang Wang,ChunYang Yang,Douglas W. Yu

Exposure of silver carp (Hypophthalmichthys molitrix) to environmentally relevant levels of cadmium: hematology, muscle physiology, and implications for stock enhancement in the Xiangjiang River (Hunan, China)

Ting Zhang,Yu Zhang,DeLiang Li,TiaoYi Xiao,Jie Li

Antigenic analysis of grass carp reovirus using single-chain variable fragment antibody against IgM from Ctenopharyngodon idella

CongLin Chen,XiaoYun Sun,LanJie Liao,ShaoXiang Luo,ZhouQuan Li,XiaoHua Zhang,YaPing Wang,QionLin Guo,Qin Fang,HePing Dai

Folate receptor-mediated boron-10 containing carbon nanoparticles as potential delivery vehicles for boron neutron capture therapy of nonfunctional pituitary adenomas

CongXin Dai,Feng Cai,Kuo Chu Hwang,YongMao Zhou,ZiZhu Zhang,XiaoHai Liu,SiHai Ma,YaKun Yang,Yong Yao,Ming Feng,XinJie Bao,GuiLin Li,JunJi Wei,YongHui Jiao,ZhenQing Wei,WenBin Ma,RenZhi Wang

Comparative analysis of de novo transcriptome assembly

Kaitlin Clarke,Yi Yang,Ronald Marsh,LingLin Xie,Ke K. Zhang

A consensus linkage map of common carp (Cyprinus carpio L.) to compare the distribution and variation of QTLs associated with growth traits

XianHu Zheng,YouYi Kuang,WeiHua Lv,DingChen Cao,XiaoFeng Zhang,Chao Li,CuiYun Lu,XiaoWen Sun

Bridging the translation gap and building the translation platform: translational medicine at Peking Union Medical College Hospital

Jun Xu,ShaoJing Liu,XueZhong Yu

Next-generation sequencing technologies for personalized medicine: promising but challenging

Geng Chen,TieLiu Shi

Critical role of bioinformatics in translating huge amounts of next-generation sequencing data into personalized medicine

HuiXiao Hong,WenQian Zhang,Jie Shen,ZhenQiang Su,BaiTang Ning,Tao Han,Roger Perkins,LeMing Shi,WeiDa Tong

mRNA enrichment protocols determine the quantification characteristics of external RNA spike-in controls in RNA-Seq studies

Tao Qing,Ying Yu,TingTing Du,LeMing Shi

Impact of the next-generation sequencing data depth on various biological result inferences

Rui Hou,ZhenXing Yang,MingHui Li,HuaSheng Xiao

Preparation and evaluation of a new releasable PEGylated tumor necrosis factor-α (TNF-α) conjugate for therapeutic application

ChuanYun Dai,Ya Fu,ShaoCheng Chen,Biao Li,Bo Yao,WanHong Liu,LiQing Zhu,Nan Chen,Ji Chen,Qiang Zhang

SIRT1 suppresses PMA and ionomycin-induced ICAM-1 expression in endothelial cells

YuYan Jia,Peng Gao,HouZao Chen,YanZhen Wan,Ran Zhang,ZhuQin Zhang,RuiFeng Yang,Xu Wang,Jing Xu,DePei Liu

Regulation of innate receptor pathways by microRNAs

Yue Zhang,YingKe Li

Four recombinant pluripotency transcriptional factors containing a protein transduction domain maintained the in vitro pluripotency of chicken embryonic stem cells

MiaoYing Yu,Song Lian,HongBing Han,Kun Yu,GuiGuan Li,ZhengXing Lian,Ning Li

The unsulfated extracellular N-terminus of vGPCR reduces the tumorigenicity of hGRO-α in nude mice

Hui Wu,YongMing Fu,Jun Xiao,Man Zhou,Wei Zhou,Hao Feng

Partitioning the effects of environmental and spatial heterogeneity on distribution of plant diversity in the Yellow River Estuary

Xiu Yuan,KeMing Ma,De Wang

Rapid progress of DNA replication studies in Archaea, the third domain of life

Yoshizumi Ishino,Sonoko Ishino

Screening for differentially expressed genes in Anoectochilus roxburghii (Orchidaceae) during symbiosis with the mycorrhizal fungus Epulorhiza sp.

Biao Li,MingJuan Tang,Kun Tang,LiFang Zhao,ShunXing Guo

Phototransduction in Drosophila

Yao Tian,Wen Hu,HuaWei Tong,JunHai Han

Roles of chromatin assembly factor 1 in the epigenetic control of chromatin plasticity

Hai Huang,RenJie Jiao

Increased COMT expression in pancreatic cancer and correlation with clinicopathologic parameters

WenMing Wu,Jie Zhang,Li Zhou,Lei You,YuPei Zhao,Ji Li

An in vivo study with an MRI tracer method reveals the biophysical properties of interstitial fluid in the rat brain

HongBin Han,Kai Li,JunHao Yan,Kai Zhu,Yu Fu

Cyprinid phylogeny based on Bayesian and maximum likelihood analyses of partitioned data: implications for Cyprinidae systematics

XuZhen Wang,XiaoNi Gan,JunBing Li,Richard L. Mayden,ShunPing He

Effects of cadmium stress on seed germination and seedling growth of Elymus dahuricus infected with the Neotyphodium endophyte

XingXu Zhang,ChunJie Li,ZhiBiao Nan

Arabidopsis F-box gene FOA1 involved in ABA signaling

Juan Peng,DaShi Yu,LiQun Wang,MinMin Xie,CongYing Yuan,Yu Wang,DongYing Tang,XiaoYing Zhao,XuanMing Liu

Bivariate genome-wide association study suggests that the DARC gene influences lean body mass and age at menarche

Rong Hai,Lei Zhang,YuFang Pei,LanJuan Zhao,Shu Ran,YingYing Han,XueZhen Zhu,Hui Shen,Qing Tian,HongWen Deng

Characterizing the induction of diabetes in juvenile cynomolgus monkeys with different doses of streptozotocin

ChunLin Zou,JiaYin Wang,ShuYan Wang,Fen Huang,ZhenHua Ren,ZhiGuo Chen,Yu Zhang

Immunocamouflage of latex surfaces by grafted methoxypoly(ethylene glycol) (mPEG): Proteomic analysis of plasma protein adsorption

Yevgeniya Le,Li Li,DunCheng Wang,Mark D. Scott

RAB-27 and its effector RBF-1 regulate the tethering and docking steps of DCV exocytosis in C. elegans

WanJuan Feng,Tao Liang,JunWei Yu,Wei Zhou,YongDeng Zhang,ZhengXing Wu,Tao Xu

Interaction between temperature and photoperiod in regulation of flowering time in rice

YuanLi Song,ZhiChao Gao,WeiJiang Luan

Sulfolobus tokodaii RadA paralog, stRadC2, is involved in DNA recombination via interaction with RadA and Hjc

Lei Wang,DuoHong Sheng,WenYuan Han,Bin Huang,ShanShan Zhu,JinFeng Ni,Jia Li,YuLong Shen

Au nanostructures: an emerging prospect in cancer theranostics

Xin Nie,ChunYing Chen

Engineering imaging probes and molecular machines for nanomedicine

Sheng Tong,Thomas J. Cradick,Yan Ma,ZhiFei Dai,Gang Bao

Progress in protein structure and function studies in China during 2010–2011

YongLin Hu

The role and clinical implications of microRNAs in hepatocellular carcinoma

Xue Zhao,Zhen Yang,GuangBing Li,DongKai Li,Yi Zhao,Yan Wu,Simon C. Robson,Lian He,YiYao Xu,RuoYu Miao,HaiTao Zhao

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