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Pharmaceuticals

ISSN Print: 1424-8247

ISSN Online:

主页: http://www.mdpi.com/journal/pharmaceuticals

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Acknowledgement to Reviewers of Pharmaceuticals in 2014

Pharmaceuticals Editorial Office

Host-Defense Peptides with Therapeutic Potential from Skin Secretions of Frogs from the Family Pipidae

J. Michael Conlon,Milena Mechkarska

Ritonavir-Mediated Induction of Apoptosis in Pancreatic Cancer Occurs via the RB/E2F-1 and AKT Pathways

Ramesh B. Batchu,Oksana V. Gruzdyn,Christopher S. Bryant,Aamer M. Qazi,Sanjeev Kumar,Sreedhar Chamala,Shu T. Kung,Ramana S. Sanka,Udaya S. Puttagunta,Donald W. Weaver,Scott A. Gruber

Are AMPA Receptor Positive Allosteric Modulators Potential Pharmacotherapeutics for Addiction?

Lucas R. Watterson,M. Foster Olive

Immunosuppressive Therapy in Immune-Mediated Liver Disease in the Non-Transplanted Patient

Anita Abhyankar,Elliot Tapper,Alan Bonder

A New Phenylpyrazoleanilide, Y-320, Inhibits Interleukin 17 Production and Ameliorates Collagen-Induced Arthritis in Mice and Cynomolgus Monkeys

Hiroyuki Ushio,Seigo Ishibuchi,Koichi Oshita,Noriyasu Seki,Hirotoshi Kataoka,Kunio Sugahara,Kunitomo Adachi,Kenji Chiba

Barriers to the Use of Trastuzumab for HER2+ Breast Cancer and the Potential Impact of Biosimilars: A Physician Survey in the United States and Emerging Markets

Philip Lammers,Carmen Criscitiello,Giuseppe Curigliano,Ira Jacobs

Design of siRNA Therapeutics from the Molecular Scale

Phillip Angart,Daniel Vocelle,Christina Chan,S. Patrick Walton

Clevidipine for Perioperative Blood Pressure Control in Infants and Children

Joseph D. Tobias,David B. Tulman,Sergio D. Bergese

RNAi Therapeutics in Autoimmune Disease

Kaleb M. Pauley,Seunghee Cha

siRNA Genome Screening Approaches to Therapeutic Drug Repositioning

Olivia Perwitasari,Abhijeet Bakre,S. Mark Tompkins,Ralph A. Tripp

Relationships between Cargo, Cell Penetrating Peptides and Cell Type for Uptake of Non-Covalent Complexes into Live Cells

Andrea-Anneliese Keller,Franziska Mussbach,Reinhard Breitling,Peter Hemmerich,Buerk Schaefer,Stefan Lorkowski,Siegmund Reissmann

Delivery of RNAi-Based Oligonucleotides by Electropermeabilization

Sophie Chabot,Sandrine Pelofy,Justin Teissié,Muriel Golzio

Dendrimers for siRNA Delivery

Swati Biswas,Vladimir P. Torchilin

A Potent (R)-alpha-bis-lipoyl Derivative Containing 8-Hydroxyquinoline Scaffold: Synthesis and Biological Evaluation of Its Neuroprotective Capabilities in SH-SY5Y Human Neuroblastoma Cells

Ivana Cacciatore,Erika Fornasari,Leonardo Baldassarre,Catia Cornacchia,Stefania Fulle,Ester Sara Di Filippo,Tiziana Pietrangelo,Francesco Pinnen

Interactions of a Dopamine D1 Receptor Agonist with Glutamate NMDA Receptor Antagonists on the Volitional Consumption of Ethanol by the mHEP Rat

Brian A. McMillen,Courtney L. Lommatzsch,Michael J. Sayonh,Helen L. Williams

Methods for Evaluating Cell-Specific, Cell-Internalizing RNA Aptamers

Luiza I. Hernandez,Katie S. Flenker,Frank J. Hernandez,Aloysius J. Klingelhutz,James O. McNamara,Paloma H. Giangrande

Nanoparticle-Based Delivery of RNAi Therapeutics: Progress and Challenges

Jiehua Zhou,Ka-To Shum,John C. Burnett,John J. Rossi

Improved Estimation of Protein-Ligand Binding Free Energy by Using the Ligand-Entropy and Mobility of Water Molecules

Yoshifumi Fukunishi,Haruki Nakamura

Toxicity Studies on Novel N-Substituted Bicyclo-Heptan-2-Amines at NMDA Receptors

Natalia Coleman,Zeynep Ates-Alagoz,Boyenoh Gaye,Michelle Farbaniec,Shengguo Sun,Adeboye Adejare

Strategies To Modulate Heritable Epigenetic Defects in Cellular Machinery: Lessons from Nature

Ganesh N. Pandian,Hiroshi Sugiyama

RNAi Therapeutic Platforms for Lung Diseases

Yu Fujita,Fumitaka Takeshita,Kazuyoshi Kuwano,Takahiro Ochiya

Stability of Recombinant Tissue Plasminogen Activator at ？30 °C over One Year

Abdulmalik Alkatheri

Advances in Mammalian Cell Line Development Technologies for Recombinant Protein Production

Tingfeng Lai,Yuansheng Yang,Say Kong Ng

Protein Kinase C Inhibitors as Modulators of Vascular Function and Their Application in Vascular Disease

Raouf A. Khalil

Biologics in Dermatology

David Chandler,Anthony Bewley

The Potential Role of Cell Penetrating Peptides in the Intracellular Delivery of Proteins for Therapy of Erythroid Related Disorders

Lefkothea C. Papadopoulou,Asterios S. Tsiftsoglou

Characterization of N-Linked Glycosylation in a Monoclonal Antibody Produced in NS0 Cells Using Capillary Electrophoresis with Laser-Induced Fluorescence Detection

Melissa Hamm,Yang Wang,Richard R. Rustandi

cGMP-Dependent Protein Kinase Inhibitors in Health and Disease

Stefanie Wolfertstetter,Johannes P. Huettner,Jens Schlossmann

Elucidating the Function of Penetratin and a Static Magnetic Field in Cellular Uptake of Magnetic Nanoparticles

Suman Chaudhary,Carol Anne Smith,Pablo del Pino,Jesus M. de la Fuente,Margaret Mullin,Andrew Hursthouse,David Stirling,Catherine C. Berry

Neurotransmitter CART as a New Therapeutic Candidate for Parkinson’s Disease

Peizhong Mao,Charles K. Meshul,Philippe Thuillier,P. Hemachandra Reddy

Cell Penetration Properties of a Highly Efficient Mini Maurocalcine Peptide

Céline Tisseyre,Eloi Bahembera,Lucie Dardevet,Jean-Marc Sabatier,Michel Ronjat,Michel De Waard

The Three Catecholics Benserazide, Catechol and Pyrogallol are GPR35 Agonists

Huayun Deng,Ye Fang

An Allosteric Modulator of the Adenosine A1 Receptor Improves Cardiac Function Following Ischaemia in Murine Isolated Hearts

Anna Butcher,Peter J. Scammells,Paul J. White,Shane M. Devine,Roselyn B. Rose'Meyer

Disease-Causing Allele-Specific Silencing by RNA Interference

Hirohiko Hohjoh

Inactivation of Caliciviruses

Raymond Nims,Mark Plavsic

NMDA Receptor Modulators in the Treatment of Drug Addiction

Seven E. Tomek,Amber L. Lacrosse,Natali E. Nemirovsky,M. Foster Olive

NMDA Receptor Antagonists for Treatment of Depression

Zeynep Ates-Alagoz,Adeboye Adejare

Glioblastoma Multiforme Therapy and Mechanisms of Resistance

Yulian P. Ramirez,Jessica L. Weatherbee,Richard T. Wheelhouse,Alonzo H. Ross

Effect of Essential Oils on Pathogenic Bacteria

Filomena Nazzaro,Florinda Fratianni,Laura De Martino,Raffaele Coppola,Vincenzo De Feo

Antimicrobial Peptides

Ali Adem Bahar,Dacheng Ren

Aptamer-Based Therapeutics: New Approaches to Combat Human Viral Diseases

Ka-To Shum,Jiehua Zhou,John J. Rossi

Loss of Response to Long-Term Infliximab Therapy in Children with Crohn’s Disease

Oliver Gouldthorpe,Anthony G. Catto-Smith,George Alex,Di Simpson

Drug Repositioning: An Opportunity to Develop Novel Treatments for Alzheimer’s Disease

Anne Corbett,Gareth Williams,Clive Ballard

Targeting Platelet Thrombin Receptor Signaling to Prevent Thrombosis

Eric L. Wallace,Susan S. Smyth

Rationale and Means to Target Pro-Inflammatory Interleukin-8 (CXCL8) Signaling in Cancer

Laura M. Campbell,Pamela J. Maxwell,David J.J. Waugh

The Inhibition of Stat5 by a Peptide Aptamer Ligand Specific for the DNA Binding Domain Prevents Target Gene Transactivation and the Growth of Breast and Prostate Tumor Cells

Axel Weber,Corina Borghouts,Christian Brendel,Richard Moriggl,Natalia Delis,Boris Brill,Vida Vafaizadeh,Bernd Groner

Personalizing Colon Cancer Therapeutics: Targeting Old and New Mechanisms of Action

Christina Leah B. Kline,Wafik S. El-Deiry

Structural and Affinity Analyses of G-Quadruplex DNA Aptamers for Camptothecin Derivatives

Hiroto Fujita,Yuri Imaizumi,Yuuya Kasahara,Shunsuke Kitadume,Hiroaki Ozaki,Masayasu Kuwahara,Naoki Sugimoto

Clinical Pharmacology of Furosemide in Neonates: A Review

Gian Maria Pacifici

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