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Frontiers in Molecular Neuroscience

ISSN Print: 1662-5099

ISSN Online:

主页: http://www.frontiersin.org/Molecular_Neuroscience/archive

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The ubiquitin-proteasome system in neurodegenerative diseases: precipitating factor, yet part of the solution

Nico P. Dantuma,Laura C. Bott

Regulation and targeting of enzymes mediating Parkinson's disease pathogenesis: focus on Parkinson's disease kinases, GTPases, and ATPases

Jean-Marc Taymans,Veerle Baekelandt,Kirsten Harvey

Guanylyl cyclase/natriuretic peptide receptor-A signaling antagonizes phosphoinositide hydrolysis, Ca2+ release, and activation of protein kinase C

Kailash N. Pandey

MicroRNAs targeting Nicastrin regulate Aβ production and are affected by target site polymorphisms

Charlotte Delay,Véronique Dorval,Sébastien S. Hébert

Physiological and pathological phosphorylation of tau by Cdk5

Koichi Ishiguro,Shin-ichi Hisanaga

Translation and silencing in RNA granules: a tale of sand grains

Jerónimo Pimentel,Graciela L. Boccaccio

Dopamine-induced tyrosine phosphorylation of NR2B (Tyr1472) is essential for ERK1/2 activation and processing of novel taste information

Orit David,Adaikkan Chinnakkaruppan,Hanoch Kaphzan,Tadashi Yamamoto,Kobi Rosenblum

Targeting GTPases in Parkinson’s disease: comparison to the historic path of kinase drug discovery and perspectives

Lin Hong,Larry A. Sklar

Early-life stress impacts the developing hippocampus and primes seizure occurrence: cellular, molecular, and epigenetic mechanisms

Li-Tung Huang

Aberrant disgust response and immune reactivity in cocaine-dependent men might uncover deranged serotoninergic activity

Carmelo M. Vicario

MicroRNA responses to focal cerebral ischemia in male and female mouse brain

Theresa A. Lusardi,Stephanie J. Murphy,Jay I. Phillips,Yingxin Chen,Catherine M. Davis,Jennifer M. Young,Simon J. Thompson,Julie A. Saugstad

Neuron-specific regulation of class I PI3K catalytic subunits and their dysfunction in brain disorders

Christina Gross,Gary J. Bassell

Life without glutamate: the epigenetic effects of glutamate deletion

Lawrence Edelstein,Kjell Fuxe,John Smythies

Dysfunction of outer segment guanylate cyclase caused by retinal disease related mutations

Patrick Z？gel,Karl-Wilhelm Koch

Chronochemistry in neurodegeneration

Annalisa Pastore,Salvatore Adinolfi

MicroRNAs in brain development and function: a matter of flexibility and stability

Philipp Follert,Harold Cremer,Christophe Béclin

miRNAs and viroids utilize common strategies in genetic signal transfer

Yuhai Zhao,Surjyadipta Bhattacharjee,Walter J. Lukiw

Predicted overlapping microRNA regulators of acetylcholine packaging and degradation in neuroinflammation-related disorders

Bettina Nadorp,Hermona Soreq

The ubiquitin proteasome system in glia and its role in neurodegenerative diseases

Anne H. P. Jansen,Eric A. J. Reits,Elly M. Hol

A central role for ubiquitination within a circadian clock protein modification code

Katarina Stojkovic,Simon S. Wing,Nicolas Cermakian

An optimal ubiquitin-proteasome pathway in the nervous system: the role of deubiquitinating enzymes

Wei-Ling Tsou,Sokol V. Todi

Cellular function and pathological role of ATP13A2 and related P-type transport ATPases in Parkinson's disease and other neurological disorders

Peter Vangheluwe

LRRK2 Kinase Activity and Biology are Not Uniformly Predicted by its Autophosphorylation and Cellular Phosphorylation Site Status

Elizabeth A. Doggett,R. Jeremy Nichols

Insights into the role of RD3 in guanylate cyclase trafficking, photoreceptor degeneration, and Leber congenital amaurosis

Laurie L. Molday,Thomas Jefferies,Robert S. Molday

LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex

Maria D. Cirnaru,Antonella Marte,Luca Murru,Luigi Bubacco,Michela Matteoli,Ernesto Fedele,Carlo Sala,Maria Passafaro,Elisa Greggio,Franco Onofri,Giovanni Piccoli

GSK-3β, a pivotal kinase in Alzheimer disease

María Llorens-Martín,Jerónimo Jurado,Félix Hernández,Jesús ávila

NF-κB signaling regulates myelination in the CNS

Thomas Blank,Marco Prinz

Regulation of neurotrophin receptor (Trk) signaling: suppressor of cytokine signaling 2 (SOCS2) is a new player

Rachel T. Uren,Ann M. Turnley

Regulation of intraocular pressure by soluble and membrane guanylate cyclases and their role in glaucoma

Emmanuel S. Buys,Louis R. Pasquale,Bruce R. Ksander

Ubiquitin Pathways in Neurodegenerative Disease

Graham Atkin

Interaction of LRRK2 with kinase and GTPase signaling cascades

Joon Y. Boon,Julien Dusonchet,Benjamin Wolozin

Distinct molecular components for thalamic- and cortical-dependent plasticity in the lateral amygdala

Osvaldo Mirante,Johannes Bohacek,Isabelle M. Mansuy

Upstream deregulation of calcium signaling in Parkinson’s disease

Pilar Rivero-Ríos,Patricia Gómez-Suaga,Elena Fdez,Sabine Hilfiker

PDE9A is Expressed in the Inner Retina and Contributes to the Normal Shape of the Photopic ERG Waveform

Anuradha Dhingra,Noga Vardi

Protein degradation and protein synthesis in long-term memory formation

Timothy J. Jarome,Fred J. Helmstetter

Neuron-specific protein interactions of Drosophila CASK-b are revealed by mass spectrometry

Konark Mukherjee,Justin B. Slawson,Bethany L. Christmann,Leslie C. Griffith

Pea3 transcription factor promotes neurite outgrowth

BASAK KANDEMIR,BERRAK CAGLAYAN,BARBARA HAUSOTT,UGUR DAG,OZLEM DEMIR,MELIS SAVASAN SOGUT,Lars Klimaschewski,ISIL AKSAN KURNAZ

Membrane Guanylate Cyclase, A Multimodal Transduction Machine: History, Present and Future Directions

Rameshwar K. Sharma,Teresa Duda

Novel roles of non-coding brain RNAs in health and disease

Hermona Soreq

Parkinson’s disease-implicated kinases in the brain; insights into disease pathogenesis.

Nicolas Dzamko,Yue Huang,Glenda Halliday

Learning improvement after PI3K activation correlates with de novo formation of functional small spines

Lilian Enriquez-Barreto,Germán Cuesto,Nuria Dominguez-Iturza,Elena Gavilán,Diego Ruano,Carmen Sandi,Gonzalo Martín-Vázquez,Oscar Herreras,Miguel Morales

Biology of Adeno-Associated Viral Vectors in the Central Nervous System

Giridhar Murlidharan,Aravind Asokan

The desferrioxamine-prochlorperazine coma—clue to the role of dopamine-iron recycling in the synthesis of hydrogen peroxide in the brain

John Smythies,Lawrence Edelstein

Atrial natriuretic factor receptor guanylate cyclase, ANF-RGC, transduces two independent signals, ANF and Ca2+

Teresa Duda,Rameshwar K. Sharma

Structural diversity of neuronal calcium sensor proteins and insights for activation of retinal guanylyl cyclase by GCAP1

Sunghyuk Lim,Alexander M. Dizhoor,James B. Ames

ROS-GC interlocked Ca2+-sensor S100B protein signaling in cone photoreceptors: review

Rameshwar K. Sharma,Clint L. Makino,David Hicks,Teresa Duda

Presynaptic [Ca2+] and GCAPs: aspects on the structure and function of photoreceptor ribbon synapses

Frank Schmitz

Mechanisms regulating neuronal excitability and seizure development following mTOR pathway hyperactivation

Candi L. LaSarge,Steve C. Danzer

Ryanodine receptor-mediated Ca2+ release underlies iron-induced mitochondrial fission and stimulates mitochondrial Ca2+ uptake in primary hippocampal neurons

Carol D. SanMartín,Andrea C. Paula-Lima,Steffen Hartel,Marco T. Nú？ez,Cecilia Hidalgo

Protein phosphatase 2A dysfunction in Alzheimer’s disease

Jean-Marie Sontag,Estelle Sontag

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