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Journal of Molecular Signaling

ISSN Print: 1750-2187

ISSN Online:

主页: http://www.jmolecularsignaling.com

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Consequences of nongenomic actions of estradiol on pathogenic genital tract response

Solar Paula,Velasquez Luis

Tumour promoting and suppressing roles of the atypical MAP kinase signalling pathway ERK3/4-MK5

Sergiy Kostenko, Gianina Dumitriu, Ugo Moens

The adaptor protein p62/SQSTM1 in osteoclast signaling pathways

Stephen McManus, Sophie Roux

The Caenorhabditis elegans D2-like dopamine receptor DOP-2 physically interacts with GPA-14, a Gαi subunit

Pratima Pandey, Singh Harbinder

Brain-derived neurotrophic factor receptor TrkB exists as a preformed dimer in living cells

Jianying Shen, Ichiro N Maruyama

Assembly of Dishevelled 3-based supermolecular complexes via phosphorylation and Axin

Noriko Yokoyama, Nelli G Markova, Hsien-yu Wang, Craig C Malbon

Akt (protein kinase B) isoform phosphorylation and signaling downstream of mTOR (mammalian target of rapamycin) in denervated atrophic and hypertrophic mouse skeletal muscle

Marlene Norrby, Kim Evertsson, Ann-Kristin Fj？llstr？m, Anna Svensson, Sven T？gerud

Coexpression of human somatostatin receptor-2 (SSTR2) and SSTR3 modulates antiproliferative signaling and apoptosis

Sajad A War, Ujendra Kumar

“Shaping” of cell signaling via AKAP-tethered PDE4D: Probing with AKAR2-AKAP5 biosensor

Salih S Kocer, Hsien-yu Wang, Craig C Malbon

Chibby suppresses growth of human SW480 colon adenocarcinoma cells through inhibition of β-catenin signaling

Victoria Fischer, Dex-Ann Brown-Grant, Feng-Qian Li

Multiple biomarker tissue arrays: A computational approach to identifying protein-protein interactions in the EGFR/ERK signalling pathway

Villaamil V,Gallego G,Valladares-Ayerbes M,Caínzos I

siRNA knockdown of GPR18 receptors in BV-2 microglia attenuates N-arachidonoyl glycine-induced cell migration

McHugh Douglas,Wager-Miller James,Page Jeremy,Bradshaw Heather B

Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to foresee the complexities of personalized medicine

Stamelos Vasileios A,Redman Charles W,Richardson Alan

Signaling in colon cancer stem cells

Roy Sanchita,Majumdar Adhip PN

The roles played by highly truncated splice variants of G protein-coupled receptors

Wise Helen

NADPH oxidase mediates the oxygen-glucose deprivation/reperfusion-induced increase in the tyrosine phosphorylation of the N-methyl-D-aspartate receptor NR2A subunit in retinoic acid differentiated SH-SY5Y Cells

Beske Phillip H,Jackson Darrell A

Canonical Wnt signaling is involved in switching from cell proliferation to myogenic differentiation of mouse myoblast cells

Shingo Tanaka, Kumiko Terada, Tsutomu Nohno

Characterization of the Rac guanine nucleotide exchange factor P-Rex1 in platelets

Joseph E Aslan, Alex M Spencer, Cassandra P Loren, Jiaqing Pang, Heidi C Welch, Daniel L Greenberg, Owen JT McCarty

E4BP4 facilitates glucocorticoid-evoked apoptosis of human leukemic CEM cells via upregulation of Bim

Jessica A Beach, Laura J Nary, Yasuko Hirakawa, Eli Holland, Rebeka Hovanessian, Rheem D Medh

Distinct roles of MK2 and MK5 in cAMP/PKA- and stress/p38MAPK-induced heat shock protein 27 phosphorylation

Alexey Shiryaev, Gianina Dumitriu, Ugo Moens

Dual function of polycomb group proteins in differentiated murine T helper (CD4+) cells

Eyal Jacob, Reut Hod-Dvorai, Or Ben-Mordechai, Yulia Boyko, Orly Avni

Rad6B acts downstream of Wnt signaling to stabilize β-catenin: Implications for a novel Wnt/β-catenin target

Brigitte Gerard, Larry Tait, Pratima Nangia-Makker, Malathy PV Shekhar

AKAP12 and AKAP5 form higher-order hetero-oligomers

Shujuan Gao, Hsien-yu Wang, Craig C Malbon

Heterodimerization of β2 adrenergic receptor and somatostatin receptor 5: Implications in modulation of signaling pathway

Rishi K Somvanshi, Nicole Chaudhari, Xiaofan Qiu, Ujendra Kumar

G-patch domain and KOW motifs-containing protein, GPKOW; a nuclear RNA-binding protein regulated by protein kinase A

Anne Aksaas, Anja CV Larsen, Marie Rogne, Ken Rosendal, Anne-Katrine Kvissel, Bj？rn Sk？lhegg

Combination of dasatinib and curcumin eliminates chemo-resistant colon cancer cells

Jyoti Nautiyal, Shailender S Kanwar, Yingjie Yu, Adhip PN Majumdar

Probing the physical nature and composition of signalsomes

Hsien-yu Wang, Craig C Malbon

Activation of K-RAS by co-mutation of codons 19 and 20 is transforming

Adam Naguib, Catherine H Wilson, David J Adams, Mark J Arends

AKAP5 and AKAP12 Form Homo-oligomers

Shujuan Gao, Hsien-yu Wang, Craig C Malbon

Genetic and functional characterization of putative Ras/Raf interaction inhibitors in C. elegans and mammalian cells

Vanessa González-Pérez, David J Reiner, Jamie K Alan, Cicely Mitchell, Lloyd J Edwards, Vladimir Khazak, Channing J Der, Adrienne D Cox

NSC109268 potentiates cisplatin-induced cell death in a p53-independent manner

Eswar Shankar, Chandreyi Basu, Brett Adkins, Wolfram Siede, Alakananda Basu

AKAR2-AKAP12 fusion protein "biosenses" dynamic phosphorylation and localization of a GPCR-based scaffold

Jiangchuan Tao, Hsien-yu Wang, Craig C Malbon

Adenoviral oncoprotein E1B55K mediates colocalization of SSBP2 and PML in response to stress

Helen B Fleisig, Hong Liang, Lalitha Nagarajan

Zinc release from thapsigargin/IP3-sensitive stores in cultured cortical neurons

Christian J Stork, Yang V Li

AMPK exerts dual regulatory effects on the PI3K pathway

Rong Tao, Jun Gong, Xixi Luo, Mengwei Zang, Wen Guo, Rong Wen, Zhijun Luo

EGFR/Met association regulates EGFR TKI resistance in breast cancer

Kelly L Mueller, Zeng-Quan Yang, Ramsi Haddad, Stephen P Ethier, Julie L Boerner

The adaptor protein SH2B1β reduces hydrogen peroxide-induced cell death in PC12 cells and hippocampal neurons

Wan-Chen Lu, Chien-Jen Chen, Hui-Chien Hsu, Hsin-Ling Hsu, Linyi Chen

Peroxisome proliferator-activated receptor gamma ligand-mediated apoptosis of hepatocellular carcinoma cells depends upon modulation of PI3Kinase pathway independent of Akt

Prajna Mishra, Suresh K Paramasivam, Ramesh P Thylur, Ajay Rana, Basabi Rana

Dishevelled-3 C-terminal His single amino acid repeats are obligate for Wnt5a activation of non-canonical signaling

Li Ma, Ying Wang, Craig C Malbon, Hsien-yu Wang

TLN-4601 suppresses growth and induces apoptosis of pancreatic carcinoma cells through inhibition of Ras-ERK MAPK signaling

Paul M Campbell, Nadia Boufaied, James J Fiordalisi, Adrienne D Cox, Pierre Falardeau, Channing J Der, Henriette Gourdeau

Chaperones contribute to G protein coupled receptor oligomerization, but do not participate in assembly of the G protein with the receptor signaling complex

Maha M Hammad, Denis J Dupré

AMPK-induced activation of Akt by AICAR is mediated by IGF-1R dependent and independent mechanisms in acute lymphoblastic leukemia

Gilles M Leclerc, Guy J Leclerc, Guilian Fu, Julio C Barredo

The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition

Su-Ni Tang, Chandan Singh, Dara Nall, Daniel Meeker, Sharmila Shankar, Rakesh K Srivastava

Novel cis-trans interactions are involved in post-transcriptional regulation of cyclin-dependent kinase inhibitor p21WAF1/CIP1 mRNA

Liyue Zhang, Anil Wali, Joseph A Fontana, Marcia I Dawson, Arun K Rishi

Transformation by a nucleotide-activated P2Y receptor is mediated by activation of Gαi, Gαq and Rho-dependent signaling pathways

Anurag Singh, José L Boyer, Channing J Der, Irene E Zohn

UV-B induced transcript accumulation of DAHP synthase in suspension-cultured Catharanthus roseus cells

Shilpa Ramani, Nandadevi Patil, Chelliah Jayabaskaran

A novel mechanism of cell growth regulation by Cell Cycle and Apoptosis Regulatory Protein (CARP)-1

Yan Jiang, Vineshkumar T Puliyappadamba, Liyue Zhang, Wenjuan Wu, Anil Wali, Michael B Yaffe, Joseph A Fontana, Arun K Rishi

Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer

Sanjit K Roy, Rakesh K Srivastava, Sharmila Shankar

Glycogen Synthase Kinase-3beta regulates Snail and beta-catenin during gastrin-induced migration of gastric cancer cells

Prajna Mishra, Subramanian Senthivinayagam, Ajay Rana, Basabi Rana

Membrane estrogen receptor-α-mediated nongenomic actions of phytoestrogens in GH3/B6/F10 pituitary tumor cells

Yow-Jiun Jeng, Mikhail Y Kochukov, Cheryl S Watson

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