Alzheimer's Research & Therapy - oalib

OALib Journal期刊
ISSN: 2333-9721
费用：99美元

投递稿件

为什么选择我们？ >>

- 开源期刊

- 同行审议

- 快速出刊

- 终身存储

- 免费检索

- 免费推广

- 更多...

- 搜索引擎

Alzheimer's Research & Therapy

ISSN Print: 1758-9193

ISSN Online:

主页: http://alzres.com

分享:

Reduction of low-density lipoprotein receptor-related protein (LRP1) in hippocampal neurons does not proportionately reduce, or otherwise alter, amyloid deposition in APPswe/PS1dE9 transgenic mice

Guilian Xu, Cameron C Green, Susan E Fromholt, David R Borchelt

Age-related increase in amyloid plaque burden is associated with impairment in conditioned fear memory in CRND8 mouse model of amyloidosis

Amanda Hanna, Kayleigh Iremonger, Pritam Das, Dennis Dickson, Todd Golde, Christopher Janus

Overlapping profiles of Aβ peptides in the Alzheimer's disease and pathological aging brains

Brenda D Moore, Paramita Chakrabarty, Yona Levites, Tom L Kukar, Ann-Marie Baine, Tina Moroni, Thomas B Ladd, Pritam Das, Dennis W Dickson, Todd E Golde

Recent Alzheimer's disease research highlights

Douglas Galasko, Todd Golde, Gordon Wilcock

Factors that influence survival in a probable Alzheimer disease cohort

Susan D Rountree, Wenyaw Chan, Valory N Pavlik, Eveleen J Darby, Rachelle S Doody

Systematic reviews on behavioural and psychological symptoms in the older or demented population

Rianne M van der Linde, Blossom CM Stephan, George M Savva, Tom Dening, Carol Brayne

Non-linear relationships of cerebrospinal fluid biomarker levels with cognitive function: an observational study

Jonathan H Williams, Gordon K Wilcock, Jeffrey Seeburger, Aimee Dallob, Omar Laterza, William Potter, A David Smith

CLU, CR1 and PICALM genes associate with Alzheimer's-related senile plaques

Eloise H Kok, Teemu Luoto, Satu Haikonen, Sirkka Goebeler, Hannu Haapasalo, Pekka J Karhunen

Should persons with autosomal dominant AD be included in clinical trials?

Joshua D Grill, John M Ringman

Right sizing funding for Alzheimer's disease

Todd E Golde, Bruce T Lamb, Douglas Galasko

Mitochondrial dysfunction - the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-β toxicity

Anne Eckert, Karen Schmitt, Jürgen G？tz

The β-secretase enzyme BACE1 as a therapeutic target for Alzheimer's disease

Robert Vassar, Patty C Kandalepas

Stem cell factor and granulocyte colony-stimulating factor reduce β-amyloid deposits in the brains of APP/PS1 transgenic mice

Bin Li, Maria E Gonzalez-Toledo, Chun-Shu Piao, Allen Gu, Roger E Kelley, Li-Ru Zhao

For debate: substituting placebo controls in long-term Alzheimer's prevention trials

René Spiegel, Manfred Berres, André R Miserez, Andreas U Monsch, the Alzheimer's Disease Neuroimaging Initiative

Validation of the relevant outcome scale for Alzheimer's disease: a novel multidomain assessment for daily medical practice

Vjera A Holthoff, Steven Ferris, Ralf Ihl, Philippe Robert, Bengt Winblad, Serge Gauthier, Kati Sternberg, Frank Tennigkeit

Should EOAD patients be included in clinical trials?

Kinga Szigeti, Rachelle S Doody

Predictors of long-term cognitive outcome in Alzheimer's disease

Carina Wattmo, ？sa K Wallin, Elisabet Londos, Lennart Minthon

PET amyloid imaging as a tool for early diagnosis and identifying patients at risk for progression to Alzheimer's disease

Michael J Pontecorvo, Mark A Mintun

What can we learn from study of Alzheimer's disease in patients with Down syndrome for early-onset Alzheimer's disease in the general population?

Robyn A Wallace, Arthur J Dalton

Amyloid imaging and memory change for prediction of cognitive impairment

Susan M Resnick, Jitka Sojkova

Investigational drugs for the treatment of AD: what can we learn from negative trials?

Sandra A Jacobson, Marwan N Sabbagh

Should persons with autosomal dominant AD be included in clinical trials? Authors' response

Kinga Szigeti, Rachelle S Doody

Can aerobic exercise protect against dementia?

Neill R Graff-Radford

Analyzing the impact of 23 mg/day donepezil on language dysfunction in moderate to severe Alzheimer's disease

Steven H Ferris, Frederick A Schmitt, Judith Saxton, Sharon Richardson, Joan Mackell, Yijun Sun, Yikang Xu

What was lost in translation in the DHA trial is whom you should intend to treat

Sally A Frautschy, Greg M Cole

Mitochondrial therapeutics in Alzheimer's disease and Parkinson's disease

Jake G Hoekstra, Kathleen S Montine, Jing Zhang, Thomas J Montine

Selectivity to amyloid-β precursor protein cleavage provides hope against Alzheimer's

Taisuke Tomita, Philip C Wong

Requiring an amyloid-β1-42 biomarker may improve the efficiency of a study, and simulations may help in planning studies

Suzanne B Hendrix

Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease

Randall J Bateman, Paul S Aisen, Bart De Strooper, Nick C Fox, Cynthia A Lemere, John M Ringman, Stephen Salloway, Reisa A Sperling, Manfred Windisch, Chengjie Xiong

A web-based normative calculator for the uniform data set (UDS) neuropsychological test battery

Steven D Shirk, Meghan B Mitchell, Lynn W Shaughnessy, Janet C Sherman, Joseph J Locascio, Sandra Weintraub, Alireza Atri

Masitinib as an adjunct therapy for mild-to-moderate Alzheimer's disease: a randomised, placebo-controlled phase 2 trial

Fran？ois Piette, Jo？l Belmin, Hélène Vincent, Nicolas Schmidt, Sylvie Pariel, Marc Verny, Caroline Marquis, Jean Mely, Laurence Hugonot-Diener, Jean-Pierre Kinet, Patrice Dubreuil, Alain Moussy, Olivier Hermine

Role of structural MRI in Alzheimer's disease

Prashanthi Vemuri, Clifford R Jack

Herbal therapy: a new pathway for the treatment of Alzheimer's disease

Jinzhou Tian, Jing Shi, Xuekai Zhang, Yongyan Wang

Obesity and the brain: a possible genetic link

Lars Bertram, Hauke Heekeren

Mild traumatic brain injury: a risk factor for neurodegeneration

Brandon E Gavett, Robert A Stern, Robert C Cantu, Christopher J Nowinski, Ann C McKee

Increasing incidence of dementia in the oldest old: evidence and implications

Bryan D James, Julie A Schneider

Inflammation in Alzheimer's disease: relevance to pathogenesis and therapy

Elina Zotova, James AR Nicoll, Raj Kalaria, Clive Holmes, Delphine Boche

The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?

Kerensa Broersen, Frederic Rousseau, Joost Schymkowitz

From model system to clinical medicine: pathophysiologic links of common proteinopathies

Pamela J McMillan, James B Leverenz

Review of Alzheimer's disease scales: is there a need for a new multi-domain scale for therapy evaluation in medical practice?

Philippe Robert, Steven Ferris, Serge Gauthier, Ralf Ihl, Bengt Winblad, Frank Tennigkeit

Dimebon disappointment

Roy W Jones

Genetics of Alzheimer disease in the pre- and post-GWAS era

Nilüfer Ertekin-Taner

Con: Can biomarkers be gold standards in Alzheimer's disease?

Kenneth Rockwood

Can novel therapeutics halt the amyloid cascade?

Niels D Prins, Pieter Visser, Philip Scheltens

Assessing the progression of mild cognitive impairment to Alzheimer's disease: current trends and future directions

Larry G Brooks, David A Loewenstein

A novel Aβ isoform pattern in CSF reflects γ-secretase inhibition in Alzheimer disease

Erik Portelius, Robert A Dean, Mikael K Gustavsson, Ulf Andreasson, Henrik Zetterberg, Eric Siemers, Kaj Blennow

Vascular health, diabetes, APOE and dementia: the Aging, Demographics, and Memory Study

David J Llewellyn, Iain A Lang, Fiona E Matthews, Brenda L Plassman, Mary AM Rogers, Lewis B Morgenstern, Gwenith G Fisher, Mohammed U Kabeto, Kenneth M Langa

Prevention of Alzheimer's disease in high risk groups: statin therapy in subjects with PSEN1 mutations or heterozygosity for apolipoprotein E epsilon 4

Daniel A Pollen, Stephen Baker, Douglas Hinerfeld, Joan Swearer, Barbara A Evans, James E Evans, Richard Caselli, Ekaterina Rogaeva, Peter St George-Hyslop, Majaz Moonis

The role of animal models in advancing amyloid-beta immunotherapy to the clinic

Dora Games, Peter Seubert

©2008-2020 OALib, Inc | Public user content licensed CC-BY 4.0 unless otherwise specified. OALib ISSN Online: 2333-9721 OALib ISSN Print: 2333-9705