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BMC Medicine

ISSN Print: 1741-7015

ISSN Online:

主页: http://www.biomedcentral.com/bmcmed

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The young osteoarthritic knee: dilemmas in management

Sutton Paul M,Holloway Edward S

RAMESES publication standards: meta-narrative reviews

Wong Geoff,Greenhalgh Trish,Westhorp Gill,Buckingham Jeanette

Plasminogen activator inhibitor-1 4G/5G polymorphism and retinopathy risk in type 2 diabetes: a meta-analysis

Zhang Tengyue,Pang Chong,Li Ningdong,Zhou Elaine

Video Q&A: Excess body weight and cancer

Kaaks Rudolf

Fat dads must not be blamed for their children's health problems

Moore Gudrun E,Stanier Philip

Multigenerational epigenetic effects of nicotine on lung function

Leslie Frances M

Economic analyses to support decisions about HPV vaccination in low- and middle-income countries: a consensus report and guide for analysts

Jit Mark,Levin Carol,Brisson Marc,Levin Ann

Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort

Soubry Adelheid,Schildkraut Joellen M,Murtha Amy,Wang Frances

Meta-analysis: implications of interleukin-28B polymorphisms in spontaneous and treatment-related clearance for patients with hepatitis C

Jiménez-Sousa María A,Fernández-Rodríguez Amanda,Guzmán-Fulgencio María,García-álvarez Mónica

Bariatric surgery: the challenges with candidate selection, individualizing treatment and clinical outcomes

Neff KJ,Olbers T,le Roux CW

Diet, a new target to prevent depression?

Sanchez-Villegas Almudena,Martínez-González Miguel A

RAMESES publication standards: realist syntheses

Wong Geoff,Greenhalgh Trish,Westhorp Gill,Buckingham Jeanette

Support of personalized medicine through risk-stratified treatment recommendations - an environmental scan of clinical practice guidelines

Yu Tsung,Vollenweider Daniela,Varadhan Ravi,Li Tianjing

Epigenetic mechanisms in migraine: a promising avenue?

Eising Else,A Datson Nicole,van den Maagdenberg Arn MJM,Ferrari Michel D

Genetics of scleroderma: implications for personalized medicine?

Assassi Shervin,Radstake Timothy RDJ,Mayes Maureen D,Martin Javier

How well do clinical prediction rules perform in identifying serious infections in acutely ill children across an international network of ambulatory care datasets?

Verbakel Jan Y,Van den Bruel Ann,Thompson Matthew,Stevens Richard

Clinical development of monoclonal antibody-based drugs in HIV and HCV diseases

Flego Michela,Ascione Alessandro,Cianfriglia Maurizio,Vella Stefano

Recent advances in the diagnosis and treatment of bladder cancer

Cheung Grace,Sahai Arun,Billia Michele,Dasgupta Prokar

Recent findings on the health effects of omega-3 fatty acids and statins, and their interactions: do statins inhibit omega-3?

de Lorgeril Michel,Salen Patricia,Defaye Pascal,Rabaeus Mikael

Collectives of diagnostic biomarkers identify high-risk subpopulations of hematuria patients: exploiting heterogeneity in large-scale biomarker data

Emmert-Streib Frank,Abogunrin Funso,de Matos Simoes Ricardo,Duggan Brian

Open access versus subscription journals: a comparison of scientific impact

Bo-Christer Bj？rk, David Solomon

The effectiveness of neuromuscular warm-up strategies, that require no additional equipment, for preventing lower limb injuries during sports participation: a systematic review

Katie Herman, Christian Barton, Peter Malliaras, Dylan Morrissey

A systematic review of the effects of residency training on patient outcomes

Renée M van der Leeuw, Kiki MJMH Lombarts, Onyebuchi A Arah, Maas Jan Heineman

Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways

Michael Maes, Michael Berk, Lisa Goehler, Cai Song, George Anderson, Piotr Ga？ecki, Brian Leonard

Treatment of enterohemorrhagic Escherichia coli (EHEC) infection and hemolytic uremic syndrome (HUS)

Paul N Goldwater, Karl A Bettelheim

Towards a genuinely medical model for psychiatric nosology

Randolph M Nesse, Dan J Stein

Frailty in primary care: a review of its conceptualization and implications for practice

Alethea Lacas, Kenneth Rockwood

Advances in sports nutrition, exercise and medicine: Olympic issues, the legacy and beyond

Mike Carmont

Ultramarathon is an outstanding model for the study of adaptive responses to extreme load and stress

Gregoire P Millet, Guillaume Y Millet

Sport and exercise medicine and the Olympic health legacy

Garry A Tew, Robert J Copeland, Simon H Till

Novel therapeutic strategies targeting HIV integrase

Peter K Quashie, Richard D Sloan, Mark A Wainberg

Comparative effectiveness of antihypertensive medication for primary prevention of cardiovascular disease: systematic review and multiple treatments meta-analysis

Atle Fretheim, Jan Odgaard-Jensen, Odd Br？rs, Steinar Madsen, Inger Nj？lstad, Ole F Norheim, Arne Svilaas, Ivar S Kristiansen, Hanne Thürmer, Signe Flottorp

Resitting a high-stakes postgraduate medical examination on multiple occasions: nonlinear multilevel modelling of performance in the MRCP(UK) examinations

IC McManus, Katarzyna Ludka

Metabolic profiling detects early effects of environmental and lifestyle exposure to cadmium in a human population

James K Ellis, Toby J Athersuch, Laura DK Thomas, Friederike Teichert, Miriam Pérez-Trujillo, Claus Svendsen, David J Spurgeon, Rajinder Singh, Lars J？rup, Jacob G Bundy, Hector C Keun

Mirroring everyday clinical practice in clinical trial design: a new concept to improve the external validity of randomized double-blind placebo-controlled trials in the pharmacological treatment of major depression

Emanuel Severus, Florian Seemüller, Michael Berger, Sandra Dittmann, Michael Obermeier, Andrea Pfennig, Michael Riedel, Sophia Frangou, Hans-Jürgen M？ller, Michael Bauer

Development and description of measurement properties of an instrument to assess treatment burden among patients with multiple chronic conditions

Viet-Thi Tran, Victor M Montori, David T Eton, Dan Baruch, Bruno Falissard, Philippe Ravaud

Born to run. Studying the limits of human performance

Andrew Murray, Ricardo J.S. Costa

Reversal of type 1 diabetes via islet β cell regeneration following immune modulation by cord blood-derived multipotent stem cells

Yong Zhao, Zhaoshun Jiang, Tingbao Zhao, Mingliang Ye, Chengjin Hu, Zhaohui Yin, Heng Li, Ye Zhang, Yalin Diao, Yunxiang Li, Yingjian Chen, Xiaoming Sun, Mary Fisk, Randal Skidgel, Mark Holterman, Bellur Prabhakar, Theodore Mazzone

Does the oxytocin receptor polymorphism (rs2254298) confer 'vulnerability' for psychopathology or 'differential susceptibility'? insights from evolution

Martin Brüne

Mitochondrial aldehyde dehydrogenase (ALDH2) protects against streptozotocin-induced diabetic cardiomyopathy: role of GSK3β and mitochondrial function

Yingmei Zhang, Sara A Babcock, Nan Hu, Jacalyn R Maris, Haichang Wang, Jun Ren

Lifestyle interventions for overweight and obese pregnant women to improve pregnancy outcome: systematic review and meta-analysis

Eugene Oteng-Ntim, Rajesh Varma, Helen Croker, Lucilla Poston, Pat Doyle

The role of nutrition in integrated programs to control neglected tropical diseases

Andrew Hall, Yaobi Zhang, Chad MacArthur, Shawn Baker

Access to preventive care by immigrant populations

Mark Harris

Novel regulatory therapies for prevention of Graft-versus-host disease

Joseph Leventhal, Yiming Huang, Hong Xu, Idona Goode, Suzanne T Ildstad

Effects of phlebotomy-induced reduction of body iron stores on metabolic syndrome: results from a randomized clinical trial

Khosrow S Houschyar, Rainer Lüdtke, Gustav J Dobos, Ulrich Kalus, Martina Broecker-Preuss, Thomas Rampp, Benno Brinkhaus, Andreas Michalsen

The Transeurope Footrace Project: longitudinal data acquisition in a cluster randomized mobile MRI observational cohort study on 44 endurance runners at a 64-stage 4,486km transcontinental ultramarathon

Uwe HW Schütz, Arno Schmidt-Trucks？ss, Beat Knechtle, Jürgen Machann, Heike Wiedelbach, Martin Ehrhardt, Wolfgang Freund, Stefan Gr？ninger, Horst Brunner, Ingo Schulze, Hans-Jürgen Brambs, Christian Billich

Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3)

Prabodh K Kandala, Sanjay K Srivastava

Outbreaks of virulent diarrheagenic Escherichia coli - are we in control?

Dirk Werber, Gérard Krause, Christina Frank, Angelika Fruth, Antje Flieger, Martin Mielke, Lars Schaade, Klaus Stark

Zinc adjunct therapy reduces case fatality in severe childhood pneumonia: a randomized double blind placebo-controlled trial

Maheswari G Srinivasan, Grace Ndeezi, Cordelia Mboijana, Sarah Kiguli, Gabriel S Bimenya, Victoria Nankabirwa, James K Tumwine

Cost-effectiveness analysis for clinicians

Suzanne R Hill

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