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Bioscience Reports

ISSN Print: 0144-8463

ISSN Online:

主页: http://www.bioscirep.org/

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ALG-2-interacting Tubby-like protein superfamily member PLSCR3 is secreted by an exosomal pathway and taken up by recipient cultured cells

Tatsutoshi Inuzuka,Akira Inokawa,Cen Chen,Kumiko Kizu

C-terminal low-complexity sequence repeats of Mycobacterium smegmatis Ku modulate DNA binding

Ambuj？K. Kushwaha,Anne Grove

The contribution of N2O3 to the cytotoxicity of the nitric oxide donor DETA/NO: an emerging role for S-nitrosylation

Ahlam？A. Ali,Jonathan？A. Coulter,Claire？H. Ogle,Marie？M. Migaud

Identification of thyroid hormone response elements in vivo using mice expressing a tagged thyroid hormone receptor α1

Susi Dudazy？Gralla,Kristina Nordstr？m,Peter？Josef Hofmann,Dina？Abdul Meseh

Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates

Christopher？G. Langendorf,Kellie？L. Tuck,Trevor？L. G. Key,Gustavo Fenalti

Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction

JingXian Fang,Takeshi Uchiumi,Mikako Yagi,Shinya Matsumoto

Different molecular mechanisms involved in spontaneous and oxidative stress-induced mitochondrial fragmentation in tripeptidyl peptidase-1 (TPP-1)-deficient fibroblasts

Guillaume Van Beersel,Eliane Tihon,Stéphane Demine,Isabelle Hamer

Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper

Sian？L. Stafford,Nilesh？J. Bokil,Maud？E. S. Achard,Ronan Kapetanovic

Neuroprotective effect of Danshensu derivatives as anti-ischaemia agents on SH-SY5Y cells and rat brain

Sunisa Seetapun,Jia Yaoling,Yang Wang,Yi？Zhun Zhu

Molecular architecture of the human protein deacetylase Sirt1 and its regulation by AROS and resveratrol

Mahadevan Lakshminarasimhan,Ute Curth,Sebastien Moniot,Shyamal Mosalaganti

Turning WAT into BAT: a review on regulators controlling the browning of white adipocytes

Kinyui？Alice Lo,Lei Sun

Integration of the metabolic/redox state, histone gene switching, DNA replication and S-phase progression by moonlighting metabolic enzymes

Hongpeng He,Mei？Chin Lee,Li？Ling Zheng,Lei Zheng

Characteristics and neural-like differentiation of mesenchymal stem cells derived from foetal porcine bone marrow

Ying Liu,Limei Liu,Xin Ma,Yupeng Yin

Identification of the kinetic mechanism of succinyl-CoA synthetase

Xin Li,Fan Wu,Daniel？A. Beard

EpCAM proteolysis: new fragments with distinct functions?

Ulrike Schnell,Jeroen Kuipers,Ben？N. G. Giepmans

Activation of blood coagulation in cancer: implications for tumour progression

Luize？G. Lima,Robson？Q. Monteiro

Characterization of the complex formed between a potent neutralizing ovine-derived polyclonal anti-TNFα Fab fragment and human TNFα

W.？Mark Abbott,Melanie Snow,Sonia Eckersley,Jonathan Renshaw

Androgen response element of the glycine N-methyltransferase gene is located in the coding region of its first exon

Cheng？Ming Lee,Chia？Hung Yen,Tsai？Yu Tzeng,Yu？Zen Huang

Designing CXCL8-based decoy proteins with strong anti-inflammatory activity in vivo

Angelika Falsone,Veronica Wabitsch,Elena Geretti,Heide Potzinger

Characterization of the bipartite degron that regulates ubiquitin-independent degradation of thymidylate synthase

Karen？W. Barbour,Yang？Yang Xing,Edsel？A. Pe？a,Franklin？G. Berger

A small organic compound enhances the religation reaction of human topoisomerase I and identifies crucial elements for the religation mechanism

Barbara Arnò,Andrea Coletta,Cinzia Tesauro,Laura Zuccaro

Requirements for the import of neisserial Omp85 into the outer membrane of human mitochondria

Christine Ott,Mandy Utech,Monika Goetz,Thomas Rudel

Transient overexpression of TGFBR3 induces apoptosis in human nasopharyngeal carcinoma CNE-2Z cells

Fangfang Zheng,Kaiwen He,Xin Li,Dan Zhao

The potential of molecular markers to improve interventions through the natural history of oesophageal squamous cell carcinoma

Nathalia？Meireles da Costa,Sheila？Coelho Soares Lima,Tatiana de Almeida Sim？o,Luis？Felipe Ribeiro Pinto

Replication stress-induced alternative mRNA splicing alters properties of the histone RNA-binding protein HBP/SLBP: a key factor in the control of histone gene expression

Alexander？M. J. Rattray,Pamela Nicholson,Berndt Müller

Functional evolution of scorpion venom peptides with an inhibitor cystine knot fold

Bin Gao,Peta？J. Harvey,David？J. Craik,Michel Ronjat

Proteolytic cleavage and truncation of NDRG1 in human prostate cancer cells, but not normal prostate epithelial cells

Mohammad？K. Ghalayini,Qihan Dong,Des？R. Richardson,Stephen？J. Assinder

Ethers and esters derived from apocynin avoid the interaction between p47phox and p22phox subunits of NADPH oxidase: evaluation in vitro and in silico

Martha？Edith Macías？Pérez,Federico Martínez？Ramos,Itzia？Irene Padilla？Martínez,José Correa？Basurto

A novel role of proteasomal β1 subunit in tumorigenesis

Fuqiang Yuan,Yana Ma,Pan You,Wenbo Lin

Polysialic and colanic acids metabolism in Escherichia coli K92 is regulated by RcsA and RcsB

Nicolás Navasa,Leandro Rodríguez？Aparicio,Miguel？ángel Ferrero,Andrea Monteagudo？Mera

Reactive centre loop mutants of α-1-antitrypsin reveal position-specific effects on intermediate formation along the polymerization pathway

Imran Haq,James？A. Irving,Sarah？V. Faull,Jennifer？A. Dickens

Crystal structure of the capsular polysaccharide synthesizing protein CapE of Staphylococcus aureus

Takamitsu Miyafusa,Jose？M. M. Caaveiro,Yoshikazu Tanaka,Martin？E. Tanner

FoxO6 and PGC-1α form a regulatory loop in myogenic cells

Shih？Ying Chung,Wei？Chieh Huang,Ching？Wen Su,Kuan？Wei Lee

Diagnostic model of saliva peptide finger print analysis of primary Sj gren's syndrome patients by using weak cation exchange magnetic beads

Pan Wei,Winston？Patrick Kuo,Feng Chen,Hong Hua

Conformational stability and activity analysis of two hydroxymethylbilane synthase mutants, K132N and V215E, with different phenotypic association with acute intermittent porphyria

Helene？J. Bustad,Marta Vorland,Eva R？nneseth,Sverre Sandberg

The down-regulation of GNAO1 and its promoting role in hepatocellular carcinoma

Xiaoyu Pei,Jun Zhang,Lijun Wu,Bin Lü

IF1, a natural inhibitor of mitochondrial ATP synthase, is not essential for the normal growth and breeding of mice

Junji Nakamura,Makoto Fujikawa,Masasuke Yoshida

The kinetic properties of a human PPIP5K reveal that its kinase activities are protected against the consequences of a deteriorating cellular bioenergetic environment

Jeremy？D. Weaver,Huanchen Wang,Stephen？B. Shears

The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2- and Akt-dependent mechanism

Tianhui Liu,Ping Wang,Min Cong,Youqing Xu

Maturation of the cytochrome cd1 nitrite reductase NirS from Pseudomonas aeruginosa requires transient interactions between the three proteins NirS, NirN and NirF

Tristan Nicke,Tobias Schnitzer,Karin Münch,Julia Adamczack

Mesenchymal stem cells overexpressing PEDF decrease the angiogenesis of gliomas

Qiaoshu Wang,Zhaoyun Zhang,Tianling Ding,Zi Chen

Kinetic mechanism of the dimeric ATP sulfurylase from plants

Geoffrey？E. Ravilious,Jonathan Herrmann,Soon Goo Lee,Corey？S. Westfall

Low-resolution structure of the soluble domain GPAA1 (yGPAA170–247) of the glycosylphosphatidylinositol transamidase subunit GPAA1 from Saccharomyces cerevisiae

Wuan？Geok Saw,Birgit Eisenhaber,Frank Eisenhaber,Gerhard Grüber

Long non-coding RNAs and their implications in cancer epigenetics

Felipe？C. Beckedorff,Murilo？Sena Amaral,Carlos Deocesano？Pereira,Sergio Verjovski？Almeida

Deleted in breast cancer-1 (DBC-1) in the interface between metabolism, aging and cancer

Eduardo？Nunes Chini,Claudia？C. S. Chini,Veronica Nin,Carlos Escande

Biochemical and biophysical characterization of four EphB kinase domains reveals contrasting thermodynamic, kinetic and inhibition profiles

Ross？C. Overman,Judit？E. Debreczeni,Caroline？M. Truman,Mark？S. McAlister

Knockdown of cathepsin D in zebrafish fertilized eggs determines congenital myopathy

Carlo Follo,Matteo Ozzano,Claudia Montalenti,Massimo？Mattia Santoro

The origin recognition complex in human diseases

Zhen Shen

Changes in retinal aquaporin-9 (AQP9) expression in glaucoma

Ming？Hui Yang,Adnan Dibas,Yu？Chang Tyan

Electrical hypothesis of toxicity of the Cry toxins for mosquito larvae

Victor？V. Lemeshko,Sergio Orduz

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