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Nov 20, 2020Open    AccessArticle

Neuroendocrine Carcinoma of the Cervix with Sister Mary Joseph's Nodule: About a Case and Literature Review

Khadija Darif, Karima Oualla, Reda El Hazzaz, Othmane Zouiten, Oumaima Siyouri, Nisrine Acharfi, Raihana Boujarnija, Lamiae Amaadour, Zineb Benbrahim, Samia Arifi, Nawfel Mellas
Neuroendocrine tumors are a rare and aggressive histological variant of the cervix, and they have several differences compared to other types of cervical cancer, in prognosis, diagnosis and treatment. In this paper we report the case of a 39-year-old patient that was taken care of in the medical oncology department at the Hassan II University Hospital Center, for an advanced neuroendocrine carcinoma of the cervix with a Sister Mary Joseph’s nodule. The aim of this work is to highlight this rare ...
Open Access Library J. Vol.7, 2020
Doi:10.4236/oalib.1106874


Oct 23, 2020Open    AccessArticle

Breast Cancer: A Review of Mammography and Clinical Breast Examination for Early Detection of Cancer

Gadafi Iddrisu Balali, Denis Dekugmen Yar, Vera Gobe Afua Dela, Emmanuel Effah-Yeboah, Philip Asumang, Justice Delali Akoto, Fuseini Abdallah
Worldwide, breast cancer is one of the most common causes of death among women. Undoubtedly, early detection of breast cancer is one of the best ways to manage and treat the disease. According to literature, Mammography and Clinical breast exams are known to be some of the best methods in early detection of breast cancer. Hence information on these two detection methods is very important for planning health policies. This study therefore aimed at reviewing the literature on breast cancer as well...
Open Access Library J. Vol.7, 2020
Doi:10.4236/oalib.1106866


Sep 27, 2020Open    AccessArticle

HPV-Positive Laryngeal Carcinomas: Epidemiological, Virological and Progressive Features

H. B. Otouana Dzon, G. C. Ngouoni, S. Diembi, G. W. Ondzotto, A. Tsierie-Tsoba, F. A. Itiere Odzili, G. Ondzotto
Objective: The aim of this work was to determine the molecular prevalence of the Human Papilloma Virus (HPV) in carcinomas of the larynx and to identify its circulating genotypes. Patients and Methods: This was a descriptive, retrospective study of 20 years which included all the patients followed in otolaryngology department for laryngeal carcinoma. The virological analysis was done on the laryngeal biopsy pieces included in paraffin using the Gene Xpert technique. This technique uses real-time...
Open Access Library J. Vol.7, 2020
Doi:10.4236/oalib.1106679


Jul 31, 2020Open    AccessArticle

Biomarker Driven Cancer Therapeutics: Existing Tools and Remaining Gaps

Sasi Shanmugam Senga, Jemma Arakelyan
Advancements in technology such as proteomics, genomics have led to the concept of personalized medicine wherein the integration of biomarkers into clinic directs cancer therapeutics. Traditional staging has a stochastic element which can only predict the outcome without actual consideration of intrapatient heterogeneity. In this review, we will look at the biomarkers that prove to be valuable tools for the personalization of cancer therapeutics among lung and breast cancer patients.
Open Access Library J. Vol.7, 2020
Doi:10.4236/oalib.1106556


Apr 20, 2020Open    AccessArticle

Orbito-Ethmoidal Rhabdomyosarcoma in an Adult Patient: A Case Report

Nguyen Tien Quang, Pham Tuan Anh, Hoang Thu Hang, Nguyen Phuong Anh
Rhabdomyosarcomas (RMS) is one of the most common sarcomas in children but rare in adults. It can occur in any anatomic location but most often presents in the head and neck region. Herewith, we report a rare case of primary orbito-ethmoidal rhabdomyosarcoma in a 29-year-old female. The patient underwent induction chemotherapy and achieved surprising results.
Open Access Library J. Vol.7, 2020
Doi:10.4236/oalib.1106263


Jan 08, 2020Open    AccessArticle

Incidence of Chemotherapy-Induced Amenorrhea in Premenopausal Patients with Breast Cancer Following Adjuvant Chemotherapy with Anthracycline and Taxane

Nguyen Tien Quang, Pham Tuan Anh, Le Van Quang, Nguyen Van Hai, Nguyen Duc Huan, Nguyen Cong Tin, Nguyen Thi Thanh Tam, Hoang Thu Hang, Nguyen Thi Thuy, Do Thi Thanh Mai, Tran Hoang Nam, Le Thi Hanga
Breast cancer (BC) is the second incidence and the fifth leading cause to cancer death in the worldwide. In developing countries, the number of BC cases is still increased annually accompanied with the changes of lifestyle and screening programs. Nevertheless, the majority of BC patients are diagnosed as non-curative stage. Thereby, systemic therapy always plays an important role in BC treatment strategies. Among chemotherapy regi
...
Open Access Library J. Vol.7, 2020
Doi:10.4236/oalib.1105999


Aug 15, 2019Open    AccessArticle

Knowledge of Risk Factors of Health Professionals towards Colorectal Cancer at the Mohammed VI Center of Casablanca for the Treatment of Cancers

Fatima Ezzahra Imad, Houda Drissi, Nezha Tawfiq, Driss Radallah, Karima Bendahhou
Introduction: Colorectal cancer (CRC) is a major public health problem in Morocco. Knowledge of risk factors is the first step in raising awareness. The objective of this work was to evaluate the knowledge of health professionals working at the Mohammed VI center for the treatment of cancers on risk factors of colorectal cancer. Patients and methods: We conducted a cross-sectional, descriptive, exhaustive study of the hospital per
...
Open Access Library J. Vol.6, 2019
Doi:10.4236/oalib.1105577


Mar 22, 2019Open    AccessArticle

Therapeutic Effect of Three-Dimensional Conformal Radiotherapy Combined with Tegafur Gimeracil and Oteracil Potassium in the Treatment of Locally Advanced Esophageal Cancer

Xiaoyan Yan, Hongsheng Yu
Objective: To observe the therapeutic effect of three-dimensional conformal radiotherapy combined with Tegafur Gimeracil and Oteracil Potassium in the treatment of locally advanced esophageal cancer. Method: The patients with locally advanced esophageal cancer admitted to our hospital were randomly divided into observation group and control group. The control group was treated with three-dimensional conformal radiotherapy alone; t
...
Open Access Library J. Vol.6, 2019
Doi:10.4236/oalib.1105303


Mar 08, 2019Open    AccessArticle

Anti-Tumor Effect and Mechanism of Parthenolide in Gastric Cancer Cellline BGC-823

Wenhao Zhu, Hanni Zhang, Yunliang Guo, Keli Ge, Yonghong Zhou
Objective: To study the anti-tumor effect and mechanism of parthenolide in gastric cancer cell BGC-823. Methods: The cck8 assay was used to detect the changes of BGC-823 cells viability after treatment with different con-centrations of parthenolide at different time points. The proliferation ability of BGC-823 cells was detected by clone formation assay. And the cell cycle and apoptosis were measured by flow cy
...
Open Access Library J. Vol.6, 2019
Doi:10.4236/oalib.1105271


Sep 26, 2018Open    AccessArticle

Mucinous Breast Carcinoma: Anatomo-Clinical Radiological and Therapeutic Features

Asma Korbi, Houda Mhabrech, Ennaceur Farouk, Ons Cherif, Amira Daldoul, Chiraz Hafsa, Ahmed Hajji, Raja Faleh
Introduction: Mucinous carcinoma of the breast constitutes 1% to 4% of all breast cancers. Two different forms of presentation are distinguished: pure mucinous carcinoma and mixed mucinous carcinoma. The purpose of our work was to clarify the anatomo-clinical and radiological particularities of this rare form of breast cancer. Materials and methods: This was a retrospective study of a series of 14 cases of mucinous carcinoma of th
...
Open Access Library J. Vol.5, 2018
Doi:10.4236/oalib.1104858


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