Loxoscelismo cutáneo

arthropod bites are very common in our surroundings; they are most often caused by insects, millipedes and arachnids (spiders and scorpions). the venom of the loxosceles genus of spiders has necrotizing, hemolytic, vasculitic and coagulant properties. the clinical picture may present itself in two distinct forms: cutaneous loxoscelism or, less frequently, cutaneous-visceral or systemic loxoscelism. in the skin, the venom can cause severe vascular changes, with areas of vasoconstriction and other areas of bleeding that rapidly lead to local ischemia and sometimes to a gangrenous plaque. we present the case of a 36-year-old woman with a left lower limb lesion, who reported having been bitten by a spider in her home. a few days later, she developed a purplish necrotic plaque with slow growing ulceration. while monitoring the lesion, the patient received two new spider bites, similar in appearance to the first one.