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Precondicionamiento isquémico a distancia en la revascularización miocárdica

Keywords: distant ischemic periods, postreperfution injury, coronary artery.

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Abstract:

introduction: a sort of distant ischemic periods could limite miocardic injury due to critical ischemic and resulting postreperfusion symdrome, previous to mayor ischemic event. objective: demostrating the eficiency of the distant ischemic precondictioning in patients with coronary revascularitation. methodologycal desing: it was used a experimental prospective method in 60 patients divived into two groups, in which revascularitation of coronary artery by graft was apply. patients with no dominant arm received a tourniquet, three insufflation shuffling with three deflating under 200 mmhg pressure, keeping it for five minutes each, previously, during and after the ischemic mayor event, by clamping the cornonary artery. results: an importat diminish of seric creatinine, cpk-mb, and inotropyc and vasoactivity drugs was achieved. a diminish of lethal ventrocularies arrythmias, out put cardiac and postperatory death was also achieved and checked, in all cases beneath the previous complicactions predicted. conclusions: the distant ischemic preconditioning can be an decisory tool to pay attention to in the antischemic protection of myocardic revascularitation.

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