Síndrome de desarrollo sexual precoz por tumor de células granulosas: presentación de un caso

we describe a case of juvenile ovarian tumor of granulose cells. its initial manifestation was an isosexual precocious puberty, in a girl aged 3 years, of a rapid and progressive evolution, associated to a palpable hypogastric mass. the hormonal assessment showed estradiol, high; 17aoh-progesterona, 13,44ng/ml, inhibited fsh, the same as lh, normal alpha fetoprotein. the imaging examination confirmed a tumoral mass in the right ovary. we extirpated the right ovary tumor of nearly 10- 12 cm , solid, well delimitated with a granulose surface, together with the tube involved in the process. the histopathologic examination showed a juvenile tumor of granulose cells. after the surgical treatment the patient has evolved satisfactorily, not showing symptoms of metastasis. the hormonal dosages were found in the normal range.