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Cáncer tiroideo recurrente: Diagnostico, tratamiento y riesgo de supervivencia

Keywords: recurrent thyroid cancer, well-differentiated thyroid carcinoma, thyroid cancer survival.

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Abstract:

background: 8 to 23% of patients suffering cdt have a recurrence. two third parties in the following 10 years after treatment. however, large part of patients have good survival. objective: to analize risk factors of survival in recurred cdt after treatment. design: retrospective - observational. setting: public tertiary care head and neck referral center. population: 114 patients with mean age 58.31 years old and 2.1 men by each one woman. 81.5% was papillary and 12.2% follicular carcinoma. in 44/114 of own serie, a total thyroidectomy was performed, extended to de lateral neck in 27.26% and trachea in 6.8%. in the rest, 50% received thyroidectomy less than total, 48.5% total thyroidectomy extended to the lateral neck in 11.7% and the trachea in 5.8%. methods: more frequent endoscopy was telelaryngoscopy followed by fibrobronchoscopy and high digestive endoscopy. computed tomography, magnetic resonance and 131i scanning were images frequently used. 24.5% of patients had a recurrent locally invasive carcinoma. surgery of recurrence was extended to cervical nodes in 94.7%, to high respiratory tract in 10.5%, to the muscles in 7.9% and it was only local in 5.2%. in 35 patients thyroidectomy was completed. results: surgery was accompanied of 24.5% complications, specially hipocalcemia in 16. 11 sequelas were reported , specially definitive hipocalcemia in 6 and recurrent laryngeal nerve paralysis in 3. 14/114 had more than 1 recurrence. in multivariate analysis age<45 years old and well-differentiated neoplasias were statiscally significative with p: 0.007 and 0.005 respectively. survival was 70% a 5 years. conclusions: morbility of surgery was higher. age<45 years old and well differentiated histology had better outcome. 5 years survival was 70%.

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