Associa？？o entre doen？a hepática gordurosa n？o alcoólica e marcadores de les？o/fun？？o hepática com componentes da síndrome metabólica em indivíduos obesos classe III

objective: to investigate the association between non-alcoholic fatty liver disease (nafld) and liver function/injury markers with components of metabolic syndrome (ms) in class iii obese individuals. methods: the study population consisted of 144 patients with class iii obesity (body mass index [bmi] > 40 kg/m2). ms was diagnosed according to the national cholesterol education program - adult treatment panel iii (ncep atp iii) criteria, by determining the lipid profile, blood glucose and basal insulin. liver function/injury markers were also quantified. insulin resistance (ir) was measured by homa-ir and nafld diagnosis was established by magnetic resonance imaging (mri). statistical calculations were performed by spss version 13.0. the association was assessed by the mann-whitney and chi-square tests, with a level of significance set at 5%. results: there was a significant association between the diagnosis of ms and nafld (χ2 = 6.84, p = 0.01). as for the diagnostic components of ms, there was a positive and significant association between hdl-c (p = 0.05), waist circumference (p < 0.05) and hypertension (χ2 = 4.195, p = 0.041) with nafld. homa-ir (p < 0.001) also showed a positive association with liver disease. conclusion: a positive and significant association between nafld and components of metabolic syndrome in class iii obese individuals was observed, suggesting the need and importance of monitoring these components for nafld screening.