Patrón de liberación de flúor in vitro en sellantes fluorados de resina

aim: to compare in vitro the amount of fluoride released from the main pit and fissure sealant resin-based on commercially available in latin america. materials and methods: twenty-eight samples of 12 x 2 mm were made from three commercial fluoridated resin-based sealants: helioseal f (hf), fissurit f (ff), clinpro (cf) and without fluoride delton (d), as a control. samples were stored in 5 ml of deionized water at 37° c and neutral ph. fluoride releases were measured at 1, 2, 3, 8, 15, 28 and 93 days with an ion-selective electrode. data were analyzed using anova and one-way and tukey (p<0.05). results: fluoride-release profiles were similar for the three fluoridated sealants: a high release rates during the first 24 hrs and then a drastic drop. afterward, they continued with a progressive decrease until day 93. the first day, ff release significantly more fluoride than hf. between days 2 and 15, cf release significantly less fluoride than ff and hf, and later, there was no significant differences between sealants (p>0.05). conclusion: the fluoride-release profile is similar for the fluoridated resin-based sealants under study: a high release during the first two days and afterwards, a very slow release. these results can explain the lack of differences in caries rate between fluoridated and non-fluoridated resin-based sealants observed in clinical trials.