Aplicación de biomateriales de base biológica, moléculas bioactivas e ingeniería de tejidos en cirugía plástica periodontal: Una revisión

objective: to describe, classify and discuss the clinical applications of biologically based biomaterials, bioactive molecules and tissue engineering being utilized in gingival recession therapy and gingival augmentation procedures in plastic periodontal surgery. in this literature review, a combination of specific search key words were used, including materials being reviewed, indicated for gingival augmentation and root coverage procedures. materials and methods: the following sources were consulted: medline, cochrane library and manual search of specific scientific journals such as journal of periodontology, international journal of periodontics and restorative dentistry and journal of clinical periodontology between the years 1985 and 2011. a total of 117 articles were reviewed with 74 being selected unanimously by the authors for discussion in the manuscript. these articles included controlled clinical studies, randomized clinical studies, case reports and animal studies. the selected articles were reviewed by the authors and accepted by consensus. conclusions: 1) there is a cohort of materials that exhibit great potential which could be a viable alternative to autografts but are in need of further long term studies. 2) there is a need of research of these materials in relation to stability, safety and efficacy.