Pre-exposure to sweeteners on glucose and sucralose consumption

previous research reported that rats demonstrated large consumptions of solutions made up with glucose and that they did not seem to show preference for solutions made up with sucralose. those findings suggested that the animals showed large consumptions of the sweet solution, as long as it contains calories. although, the sequence to which the animals are exposed could contribute on the observation of these responses: history of flavor consumption may alter the consumption of new foods. in the present study, a group of rats was exposed to two sweeteners: glucose and sucralose at different times, with the purpose of determining whether the history of consumption of a sweetener with calories may modify the consumption of another sweetener without calories, and vice versa. the results demonstrated that the subjects showed great consumptions of glucose, regardless of the previous exposure to sucralose, and that the consumption of sucralose was not affected by the previous consumption of the glucose. these findings suggest that the previous consumption of sugars seems not to have an effect on subsequent sweet solution consumption.