Extracto metanólico de Datura stramonium para el control in vitro e in vivo de Ramularia cercosporelloides, agente causal de la falsa cenicilla del cártamo (Carthamus tinctorius)

the safflower production in the mexican state of sonora has been significantly affected by a new fungal disease caused by ramularia cercosporelloides. producers have been applied several fungicide treatments which implies high economic investment and high risk for environment pollution. the aim of this study was to evaluate the potential antifungal activity of the methanolic extract of datura stramonium as an alternative to control this fungus. the effect of the methanolic extract on the radial growth kinetic, biomass production and the concentration required to delay 50% (cr50) of radial growth were determined. an in vivo test was done to evaluate the effect of the methanolic extract on the safflower seed germination. the methanolic extract 10%, v/v caused 75.0% inhibition on the fungal growth at 96 h of incubation in media v8. when the cr50 (3.0%, v/v) was applied the radial inhibition was 32.0%. the methanolic extract did not affect the biomass production. the safflower seed germination was not affected by the methanolic extract because most of the s normally developed.