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Resultados de las peticiones de anticuerpos tiroideos en un Hospital Provincial de Castilla-León

Keywords: antithyroid peroxidase antibodies (tpo-ab), antithyroglobulin antibodies (tg-ab), tsh-receptor antibodies (tr-ab), hyperthyroidism, hypothyroidism.

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Abstract:

objectives: to evaluate if simultaneous determination of both tpoab and tgab is clinically more adequate than single determination of tpoab. materials and methods: quantification using a microplate immunoassay of 1236 samples in which an autoimmune thyroid protocol was requested (tpoab and tgab). results: patients were classified by positive or negative results of both tpoab and tgab as follows: tpoab (-) - tgab (-), 61.4%; tpoab (+) - tgab (-), 22.8%; tpoab (+) - tgab (+), 13.6% and tpoab (-) - tgab (+), 2.2%; a higher prevalence of positive results was observed in women in comparison to men 30% n 6.3% for tpoab and 13.6%n 2.2% for tgab. conclusions: the simultaneous protocol (tpoab and tgab) for thyroid autoimmune diseases have no more clinical usefulness than a single protocol (tpoab). the first one protocol must be reserved for concrete clinical situations as differentiated thyroid cancer whereas the single one (tpoab) could be implanted on routine.

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