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Long-Term Treatment of Metastatic Colorectal Cancer with PanitumumabDOI: 10.4137/CMO.S5055 Abstract: Colorectal cancer is one of the leading causes of cancer-related deaths worldwide. More than 30% patients present with metastases at diagnoses and will require systemic chemotherapy. In recent years many anti-EGFR targets have been developed. Among them, panitumumab, a fully human IgG2 monoclonal antibody has shown important benefits in the treatment of this disease.
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