Congenital chloride diarrhea: late presentation

ngenital chloride diarrhea: late presentation Case report (2955) Total Article Views Authors: Al Bishi L, Al Toonisi M Published Date April 2011 Volume 2011:2 Pages 35 - 38 DOI: http://dx.doi.org/10.2147/PHMT.S16180 Laila Al Bishi1, Mustafa Al Toonisi2 Pediatric Department, North West Armed Forces Hospital, Tabuk, Kingdom of Saudi Arabia Abstract: We report the case of a male infant who presented with diarrhea at 6 months of age. He was failing to thrive, and biochemical investigation revealed hypokalemic hypochloremic metabolic alkalosis. Diagnosis of congenital chloride diarrhea was suspected and confirmed by the stool chloride result. He was started on high-dose sodium chloride and potassium chloride to control the electrolyte imbalance. The disease was difficult to control for a year after diagnosis. Late presentation is associated with severe chronic electrolyte disturbances and high-dose replacement therapy.