Antibiotic Resistance Profile of Gram Negative Bacteria Isolated from Surgical Wounds in Minna, Bida, Kontagora and Suleja Areas of Niger State

Antibiotics resistance profiles of bacteria from surgical wounds were investigated in four (4) General Hospitals (Bida, Kontagora, Minna and Suleja) in Niger State. Five hundred (500) samples (i.e. Two hundred (200) samples in Minna, One hundred (100) samples each Suleja, Kontagora and Bida) of wound exudates from these general hospitals, were analysed. The results showed the presence of Klebsiella Pneumoniae, Escherichia coli, Pseudomonas aeruginosa, and Proteus vulgaris in the samples from the wounds. From the five hundred (500) samples collected from all locations, forty two (42) samples had Kl. pneumoniae, sixty four (64) samples had Ps. aeruginosa, fifty two (52) samples had P. vulgaris and one hundred and nine (109) samples had E. coli. E. coli was the most frequently isolated bacteria from wounds in all the locations, while Kl. pneumoniae was the least isolated from wounds in all the locations. All the bacteria were tested for sensitivity against tarivid, pefloxacin, ciprofloxacin, augmentin, gentamycin, streptomycin, ceporex, nalidixic acid, septrin, ampicillin, ampiclox, zinacef, amoxacillin, rocephin, erythromycin. Most of all the isolates were sensitive to ciprofloxacin, pefloxacin and Tarivid while others were resistant to remaining antibiotics. E. coli, Strept. pyogenes and S. aureus showed highest resistance profile and P. vulgaris, Kl. pneumoniae and Ps. aeruginosa showed least resistance profile to most antibiotics used.