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Facile Method of Quinoxaline Synthesis Using Phenol as a New, Efficient and Cheap Catalyst at Room Temperature

DOI: 10.5923/j.ajoc.20120204.04

Keywords: Quinoxaline, Phenol, 1,2-Diamine, Α-Diketone, Green Chemistry

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Abstract:

Abstarct A simple, highly efficient and green procedure for the condensation of aryl and alkyl 1,2-diamines with α-diketones in the presence of catalytic amount of phenol(20 mol%) at room temperature is described. Using this method, quinoxaline derivatives as biologically interesting compounds are produced in high to excellent yields and short reaction times.

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