Correlation of P-wave Duration and Dispersion in Patients with Ischemia-Induced During Treadmill Exercise Testing with Duke Score

Prolonged P-wave duration and dispersion have been reported during transient coronary artery occlusions such as angioplasty, spontaneous angina episodes and exercise induced myocardial ischemia. The association of Duke score and P-Wave Dispersion (PWD) has been poor explored. To determine the correlation of Duke score with PWD during Treadmill Exercise Testing (TET) and this sensitivity. Study population included 78 patients with suspected coronary artery disease (64 men, mean age 53.3 years) who had underwent TET. The P-wave duration was calculated in at least eight derivations before exercise and at mean 4 min of recovery by two investigators independently. Duke score, exercise capacity and Cornell voltage were calculated. PWD were found to be significantly higher at recovery (p = 0.008) than at rest and in patients with ischemia-induced than those without ischemia-induced during exercise (p = 0.003) at recovery. There was no difference about measurements of P-wave at rest and use of beta-blocker, the Cornell voltage and exercise capacity. There was no influence of age and gender. Pearson s coefficient between Duke score and PWD at recovery was 0.005. At increase of 12 msec in this measurement, the analysis with receiver operator characteristic curve provides a sensitivity of 97% and a specificity of 96% for exercise positive response and 95 and 97%, respectively, for Duke scores ≤4. There was a significant increase in PWD at recovery in patients with exercise positive test. There was correlation between PWD and Duke score with increase of accuracy of TET.