Research Progress in Developmental Neurotoxicity of Perfluorinated Compounds
全氟化合物发育神经毒性研究进展

Widely used in industrial production and life, some of the perfluorinated compounds (PFCs) have become a class of ubiquitous pollutants in the environment. Due to globally distribution, environmentally persistence and bioaccumulation of PFCs, the toxicity of PFCs has raised increasing concern. Recent results of study show that PFCs have developmental neurotoxicity besides significant toxicity on the liver, immune, reproductive and endocrine systems. In this paper, the research progress in developmental neurotoxicity of PFCs in recent years were outlined, and the several mechanisms of PFCs developmental neurotoxicity of PFCs were discussed. Additionally, the problems in the future research in this field were analyzed. To promote the further understanding of neural damages of PFCs in the real environment, it was suggested that research in developmental neurotoxicity of PFCs at environmental relevant dose should be strengthened. The developmental neurotoxicity induced by combined exposure to PFCs and other neurotoxicants should be concerned.