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波谱学杂志 2010
A Cell Perfusion System for Online NMR Studies
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Abstract:
A cell perfusion system for online NMR studies is reported. The system was used to measure 31P NMR signals of ATP in living breast cancer cells (MCF-7), with or without perfusion with cantharidin solution. The results- showed that online NMR on perfused cell culture is an effective way to identify active components from extracts of traditional Chinese medicine. The method can also be used to study the interactions between drugs and cancer cells.