Trefoil Factor: from Laboratory to Clinic
三叶因子:从实验室研究到临床医学

Trefoil factor (TFF) family is a group of peptides with one or several trefoil factor domains in their structure,which are highly conserved in evolution,and are characterized by heat and enzymatic digestion resistance.The mammalian TFFs have three members(TFF1-3),and the gastrointestinal tract and the airway system are major organs of their expression and secretion.At certain physiological conditions,with a tissue-specific distribution,TFF plays an important role in mucosal protection and wound healing.But ...